Eight drops contain: Sodium Chlorite (Chlorine Dioxide Precursor) 2.5% • Purified Water 97.5%.
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Below is general information about the effectiveness of the known ingredients contained in the product Optimal OxyPure. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Optimal OxyPure. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when solutions containing 0. 01% to 0.8% chlorine dioxide are used topically as mouthwash. The solution has been swished around the mouth for 30-60 seconds and spit out, once or twice daily, for up to 10 days with apparent safety (102812,102813,102814,102815,102816,102817). ...when a 0.005% solution is used topically for wound irrigation. In one clinical study, a single irrigation with 100-200 mL was used without reported adverse effects (102818).
LIKELY UNSAFE ...when used orally for medicinal purposes. Although chlorine dioxide is used in public water treatment facilities as a disinfectant, the US Environmental Protection Agency (EPA) limits the maximum concentration of chlorine dioxide and chlorite in drinking water to a level that has demonstrated safety with regular use (102803,102805,102811). This safe level is 0.8 mg chlorine dioxide per liter (0.00008%) or 1 mg chlorite per liter (0.0001%). Higher levels of chlorine dioxide can irritate the mouth, esophagus, and stomach (102811). Chlorine dioxide supplements typically contain 28% sodium chlorite, which can provide 3-8 mg of chlorine dioxide per drop when mixed with citric acid as directed. At these doses, chlorine dioxide has been reported to cause serious complications, including severe vomiting and diarrhea, life-threatening low blood pressure, hemolysis, and acute liver failure (102807,102808,102810). ...when inhaled. Occupational and accidental exposure to chlorine dioxide gas can cause lung irritation and long-term respiratory complications (102806,102811).
CHILDREN: LIKELY UNSAFE
when used orally for medicinal purposes.
Chlorine dioxide supplement products typically contain 28% sodium chlorite, which can provide 3-8 mg of chlorine dioxide per drop when mixed with citric acid as directed. At these doses, chlorine dioxide has been reported to cause serious complications, including severe vomiting and diarrhea, life-threatening low blood pressure, hemolysis, and acute liver failure (102807,102808,102810). There is insufficient reliable information available about the safety of chlorine dioxide when used topically; avoid using.
PREGNANCY AND LACTATION: LIKELY UNSAFE
when used orally for medicinal purposes.
Chlorine dioxide supplement products typically contain 28% sodium chlorite, which can provide 3-8 mg of chlorine dioxide per drop when mixed with citric acid as directed. Chlorine dioxide has been reported to cause serious complications, including severe vomiting and diarrhea, life-threatening low blood pressure, hemolysis, and acute liver failure (102807,102808,102810). There is insufficient reliable information available about the safety of chlorine dioxide when used topically; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Optimal OxyPure. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the adverse effects of the known ingredients contained in the product Optimal OxyPure. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, chlorine dioxide supplements are generally considered unsafe and can cause serious adverse effects.
Topically, adequately diluted chlorine dioxide seems to be well tolerated.
Most Common Adverse Effects:
Orally: When consumed in amounts commonly found in supplements, chlorine dioxide can cause diarrhea, irritation of the mouth, esophagus, and stomach, hemolysis, hypotension, liver failure, and vomiting.
Cardiovascular ...Orally, consuming large quantities of chlorine dioxide has been reported to cause life-threatening hypotension (102810).
Dermatologic ...Case reports have described toxic irritant dermatitis associated with topical exposure to chlorine dioxide (108747).
Gastrointestinal ...Orally, consuming chlorine dioxide in quantities exceeding the maximum allowable concentration can irritate the mouth, esophagus, and stomach (102811). Consuming large quantities of chlorine dioxide has been reported to cause severe vomiting and diarrhea (102810).
Hematologic ...Orally, chlorine dioxide has been reported to cause hemolysis. In one case series, two healthy adults presented with reddish urine, jaundice, tachycardia, and tachypnea three days after ingesting 100 mL each of chlorine dioxide 2% solution. Hemolysis resolved after 7 days (102807). Patients with G6PD deficiency are at increased risk for hemolysis with chlorine dioxide. There are multiple reports of patients with G6PD deficiency experiencing hemolysis after consuming chlorine dioxide as Miracle Mineral Solution (MMS) (102809,102820). There is also a case report of a 55-year-old male who developed disseminated intravascular coagulation and acute kidney injury requiring hemodialysis after taking an unknown dose of chlorine dioxide orally daily for 5 days for prophylaxis of COVID-19 (108746). Other case reports have described methemoglobinemia and hemolytic anemia (108747).
Hepatic ...Orally, consuming large quantities of chlorine dioxide has been reported to cause acute liver failure (102810).
Pulmonary/Respiratory ...Occupational and accidental inhalation of chlorine dioxide gas can cause lung irritation and long-term respiratory complications (102806,102811).
Renal ...A 55-year-old male who took an unknown dose of chlorine dioxide orally daily for 5 days as prophylaxis for COVID-19, presented with nausea and vomiting, dehydration, altered mental status, disseminated intravascular coagulation, and acute kidney injury requiring hemodialysis (108746).
Other
...Orally, chlorine dioxide solution in doses of up to 10 mL diluted in 1 liter of water, consumed over 8 hours daily for 9 months, has resulted in fatal toxicity.
A 65-year-old male presented with nausea and vomiting, melena, drowsiness, hypotension, tachycardia, electrolyte imbalance, peritoneal irritation, absent peristalsis, abdominal distension due to fluid accumulation, and perforation of the jejunum. After gastrointestinal surgery, the patient developed septic shock with multiple organ failure, leading to death (108748).
Orally, chlorine dioxide has been reported to cause Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) in one patient. A 41-year-old female presented with fever and lymphadenopathy after consuming "one glassful" of chlorine dioxide as Miracle Mineral Solution (MMS). The disease may have been triggered by oxidative injury from chlorine dioxide, leading to an inflammatory response (102808).
