| Ingredients | Not Present |
|---|---|
| 50 mg |
Microcrystalline Cellulose, Phosphatidylcholine Note: 75%, Hydroxypropyl Beta Cyclodextrin (Alt. Name: HPBetaCD), Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Red #40
This product contains one or more ingredients that appears to be a prohormone. Prohormones are typically designed to be metabolized to anabolic compounds (91094,91095). Although there is very little known about these compounds they may cause serious anabolic steroid-like side effects including stroke, kidney failure, and liver injury. Advise patients not to take this product.
Below is general information about the effectiveness of the known ingredients contained in the product 1-Andro. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the interactions of the known ingredients contained in the product 1-Andro. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion (90399,91095). Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
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Below is general information about the adverse effects of the known ingredients contained in the product 1-Andro. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Clinical evidence evaluating the safety of 1-androsterone is lacking. However, in one preliminary clinical study, low-density lipoprotein (LDL) cholesterol levels were increased and high-density lipoprotein (HDL) cholesterol levels were decreased. Some patients also developed indicators of liver and kidney damage. In these patients, the liver enzyme aspartate transaminase (AST) and serum creatinine were significantly increased (91095).
Cardiovascular ...Significant increases in LDL cholesterol of around 29 mg/dL and significant decreases in HDL cholesterol of around 19 mg/dL have been reported in patients taking 1-androsterone for 4-weeks (91095).
Hepatic ...Significant increases in AST of around 15. 4 IU/L have been reported in patients taking 1-androsterone daily for 4 weeks. Despite the elevation, average AST levels did not go much beyond 40 IU/L, the upper limit of normal for AST (91095).
Renal ...Significant increases in serum creatinine of around 0. 2 mg/dL and significant decreases in GFR of around 16.4 mL/min/1.72m2 have been reported in patients taking 1-androsterone for 4 weeks. Serum creatinine remained within normal range despite the elevation, GFR dropped below 89 mL/min/1.72m2, which is suggestive of renal impairment (91095).
