Ingredients | Amount Per Serving |
---|---|
(Grifola frondosa Fruiting Body Extract)
(Yielding)
|
30 mg |
D-Fraction
|
9 mg |
(DMG)
|
450 mg |
Glycerin, Water, Rosmarinic Acid
Below is general information about the effectiveness of the known ingredients contained in the product Acute Immune Benefits Liquid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Acute Immune Benefits Liquid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used orally, short-term. Dimethylglycine has been used with apparent safety in small clinical trials lasting up to 28 days (5819,5823).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
POSSIBLY SAFE ...when used orally and appropriately as extracts. A maitake mushroom extract 3 mg/kg twice daily has been used safely for up to 12 weeks (92843). Doses up to 5 mg/kg twice daily of another maitake mushroom extract have been used safely for up to 3 weeks (61239). Maitake mushroom polysaccharides (MMP) 1-1.5 grams daily have also been used safely for up to 2 years (8188).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Acute Immune Benefits Liquid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Details
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes (8188).
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Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Details
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There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
Details
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects (17209).
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Below is general information about the adverse effects of the known ingredients contained in the product Acute Immune Benefits Liquid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, no adverse effects have been reported in clinical trials in adults and children using dimethylglycine. However, a thorough evaluation of safety outcomes has not been conducted.
Gastrointestinal ...Theoretically, dimethylglycine might react with nitrites in the gastrointestinal tract to form carcinogenic substances (5827). However, research suggests that dimethylglycine does not react with nitrites and is not carcinogenic (13172).
General
...Orally, maitake mushroom is generally well tolerated.
Most Common Adverse Effects:
Orally: Gastrointestinal effects, including diarrhea and epigastric pain.
Dermatologic ...In a clinical trial, one patient experienced rash and pruritus after two doses of maitake mushroom polysaccharide extract. The allergic reaction cleared without intervention (61239).
Gastrointestinal ...In clinical research of a polysaccharide extract from maitake mushroom, one patient reported nausea (61239) and 2 out of 26 reported epigastric pain (17131). In a clinical trial of a liquid extract from maitake mushroom, 2 out of 21 patients experienced diarrhea, and one experienced nausea. One patient withdrew from the study due to diarrhea (92843).
Immunologic ...In a clinical trial of a liquid extract from maitake mushroom, 4 out of 21 patients experienced eosinophilia (92843).
Musculoskeletal ...In a clinical trial of a polysaccharide extract from maitake mushroom, one patient reported joint swelling (61239).
Pulmonary/Respiratory ...There is one case of occupational hypersensitivity pneumonitis (HP) caused by maitake mushroom spores (61228).