Damiana Aphrodisiaca • Tribulus terrestris • Muira Puama • Live Bio Active Kombucha .
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
Below is general information about the effectiveness of the known ingredients contained in the product Damiana Aphrodisiaca Complex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Damiana Aphrodisiaca Complex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Damiana has Generally Recognized As Safe status (GRAS) for use in foods in the US (4912).
POSSIBLY SAFE ...when used orally and appropriately in medicinal amounts (12,46933,11866).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
POSSIBLY SAFE ...when consumed orally after being properly and hygienically prepared (2650,2651,2652,2653).
POSSIBLY UNSAFE ...when non-sterile home preparations are consumed orally. These preparations are at risk for contamination with opportunistic pathogens (2650,2651,2652,2653).
LIKELY UNSAFE ...when consumed orally after being prepared or stored in a container with toxic constituents, such as lead glaze (1366,2655). Lead poisoning was reported in two people who consumed kombucha prepared in a lead-glazed ceramic pot for six months (1366).
PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when used orally; avoid using.
POSSIBLY SAFE ...when used orally and appropriately, short-term. Taking muira puama 500-1050 mg daily, as part of a combination product, has been used with apparent safety for 1 month (63920,103224). There is insufficient reliable information available about the safety of muira puama when used long-term.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
LIKELY UNSAFE ...when the spine-covered fruit is used orally. There have been reports of bilateral pneumothorax and bronchial polyp after oral consumption of the spine-covered fruit (818).
PREGNANCY: POSSIBLY UNSAFE
when used orally.
Animal research suggests that tribulus might adversely affect fetal development (12674); avoid using.
LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Damiana Aphrodisiaca Complex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, damiana may lower blood glucose levels (4,25016). This might increase the risk of hypoglycemia in patients taking antidiabetes drugs.
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Some antidiabetes drugs include glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTabs, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
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Theoretically, kombucha might increase the risk of hypoglycemia when taken with antidiabetes drugs.
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Theoretically, kombucha might cause a disulfiram reaction when taken with disulfiram.
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Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
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Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications (97327).
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Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
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Theoretically, tribulus might increase the levels and clinical effects of lithium.
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Tribulus is thought to have diuretic properties (12681). Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
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Below is general information about the adverse effects of the known ingredients contained in the product Damiana Aphrodisiaca Complex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, damiana is generally well tolerated. In a rare case, 200 grams of damiana extract has caused tetanus-like convulsions and paroxysms resulting in symptoms similar to rabies or strychnine poisoning (4).
Neurologic/CNS ...Orally, 200 grams of damiana extract has caused tetanus-like convulsions and paroxysms resulting in symptoms similar to rabies or strychnine poisoning (4).
General
...Orally, kombucha seems to be well tolerated.
However, kombucha that is prepared in non-sterile environments or stored in containers made with toxic constituents might be unsafe.
Most Common Adverse Effects:
Orally: Gastrointestinal complaints, including nausea and vomiting.
Serious Adverse Effects (Rare):
Orally: Cardiac arrest and death.
Cardiovascular ...Two cases of cardiac arrest, one resulting in death, possibly associated with kombucha consumption have been reported (2655,57764).
Dermatologic ...In one case report, topical application of kombucha was associated with cutaneous anthrax infection. However, the kombucha could have been contaminated due to unhygienic preparation conditions (2651,57733,57767).
Endocrine ...In one case, a 22 year-old male with HIV presented with hyperthermia, lactic acidosis, and acute renal failure 15 hours after ingesting kombucha (57748).
Gastrointestinal ...Orally, use of kombucha has been associated with reports of stomach problems, nausea, and vomiting (2652,2656,57733,57742). The acidic content of kombucha increases with the duration of fermentation during preparation, which may contribute to development of stomach ulcers (103179).
Hepatic ...Two cases of hepatotoxicity likely related to contaminated kombucha consumption for a month or more have been reported (57761,57733,94519).
Musculoskeletal ...Head and neck pain associated with consumption of kombucha was described in a single patient (2656,57733). In one case, a male developed anti-Jo1 antibody-positive myositis after drinking kombucha (57737).
Neurologic/CNS ...Dizziness associated with consumption of kombucha, possibly due to its alcohol content, has been reported (57733,57762).
Renal ...In one case, a 22 year-old male with HIV presented with hyperthermia, lactic acidosis, and acute renal failure 15 hours after ingesting kombucha (57748).
Other ...Due to the acidic nature of kombucha, toxic elements present in storage containers may leach into the product (2655). In one report, symptomatic lead poisoning requiring chelation decontamination therapy occurred in two people who consumed kombucha prepared in a lead-glazed ceramic pot for six months (1366).
General ...No adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted.
General
...Orally, tribulus seems to be well tolerated.
Serious Adverse Effects (Rare):
Orally: Cases of liver and kidney injury, seizures, and chronic painful erection with impaired sexual function have been reported. Pneumothorax and bronchial polyp after consuming the spine-covered tribulus fruit have been reported.
Gastrointestinal ...Orally, tribulus can cause abdominal pain, cramping, nausea, vomiting, diarrhea, and constipation (92022,92027). However, in one study, the rates of these gastrointestinal complaints were similar for patients taking tribulus and those receiving placebo (92022).
Genitourinary ...In one case report, a patient taking two tribulus tablets (unknown dose) daily for 15 days presented to the local emergency department with a painful erection lasting 72 hours. The priapism was resolved with medical management; however, post-episode sexual function was impaired (92023).
Hepatic ...In one case report, a patient drinking tribulus water 2 liters daily for two days presented with lower limb weakness, seizures, hepatitis, and acute kidney injury. The patient's condition improved after hemodialysis and discontinuation of tribulus water (92069).
Neurologic/CNS ...Orally, tribulus has been reported to cause general excitation and insomnia. These symptoms were reversed upon discontinuation of the drug or decreasing the dose (78867). In one case report, a patient drinking tribulus water 2 liters daily for two days presented with lower limb weakness, seizures, hepatitis, and acute kidney injury. The patient's condition improved after hemodialysis and discontinuation of tribulus water (92069).
Pulmonary/Respiratory ...In one case report, a patient developed a bilateral pneumothorax after consuming the spine-covered fruit of tribulus (818). In another case report, a patient developed a polyp in the lobar bronchus of the right interior lobe due to the presence of a tribulus fruit spine (78852).
Renal ...In one case report, a patient drinking tribulus water 2 liters daily for two days presented with lower limb weakness, seizures, hepatitis, and acute kidney injury. The patient's condition improved after hemodialysis and discontinuation of the tribulus water (92069). In another case report, a healthy male taking one tribulus tablet (unknown dose) daily for a few months for bodybuilding purposes developed hyperbilirubinemia followed by acute kidney failure 2-3 weeks later. The patient was managed with intravenous fluids and a low-salt, low-protein diet (92025).
Other ...In one case report, gynecomastia was observed in a male weightlifter taking an herbal combination product containing tribulus. However, it is not clear if this adverse effect can be attributed to tribulus alone (78859).
