Each capsule contains: sgs brand Broccoli seed concentrate (standardized to contain 30 mg glucoraphanin glucosinolate) 300 mg • Wasabia japonica extract 80 mg. Other Ingredients: Hypromellose, Sorbitol, Silicon Dioxide, Water.
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Below is general information about the effectiveness of the known ingredients contained in the product Sulforaphane+. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Sulforaphane+. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in food amounts (14145). There is insufficient reliable information available about the safety of broccoli when used in medicinal amounts.
PREGNANCY AND LACTATION: LIKELY SAFE
when used orally in food amounts (14145).
There is insufficient reliable information available about the safety of broccoli when used in medicinal amounts during pregnancy and lactation; avoid using.
LIKELY SAFE ...when used orally in food amounts (29994). When used orally and appropriately in medicinal amounts, short-term, wasabi extract 600 mg once daily has been safely used for up to 4 weeks (112846).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Sulforaphane+. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
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Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
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Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents (19608).
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Theoretically, wasabi might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
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In vitro research shows that 6-(methylsulfinyl) hexyl isothiocyanate, a constituent of wasabi, inhibits platelet aggregation (29143).
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Below is general information about the adverse effects of the known ingredients contained in the product Sulforaphane+. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Broccoli is well tolerated when consumed as food. A thorough evaluation of safety outcomes when broccoli is taken as medicine has not been conducted.
Dermatologic ...Topically, allergic reactions to broccoli have caused contact dermatitis (14158).
Hepatic ...In one case report, a 56-year-old adult developed elevated transaminases, with alanine aminotransferase (ALT) 5. 8 times above normal, aspartate aminotransferase (AST) 2.4 times above normal, and gamma-glutamyl transpeptidase (GGT) 5.1 times above normal. This was thought to be related to the consumption of 800 mL of broccoli juice daily over a 4-week period. Values returned to normal 15 days after cessation of juice consumption (96191).
Immunologic ...Topically, allergic reactions to broccoli have caused contact dermatitis (14158).
General ...Orally, wasabi seems to be well tolerated in medicinal amounts.
Endocrine ...A small clinical study in adults taking oral wasabi extract 2000 mg once daily for 4 weeks has found 1 case of ketone bodies in the urine (112846).
Hepatic ...A small clinical study in adults taking oral wasabi extract 1000 mg once daily for 4 weeks has found 1 case of mildly elevated alanine transaminase and aspartate transaminase levels (112846).
Musculoskeletal ...A small clinical study in adults taking oral wasabi extract 2000 mg once daily for 4 weeks has found 1 case of elevated creatine phosphokinase (112846).
Renal ...A small clinical study in adults taking oral wasabi extract 1000 mg once daily for 4 weeks has found 2 cases of proteinuria (112846).