Each capsule contains: Shark Cartilage [poly-(1->3)-N-acetyl-2-amino-2-deoxy-3-O-ß-D-glucopyranurosyl-4-(or 6-)sulfonyl-D-galactose] 57 mg. Other Ingredients: Gelatin, Magnesium Stearate, MIcrocrystalline Cellulose, Purified Water.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
Below is general information about the effectiveness of the known ingredients contained in the product Shark Cartilage. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Shark Cartilage. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used orally and appropriately, short-term. Shark cartilage has been used with apparent safety in clinical trials lasting up to 24 weeks (2015,4893,4938,6709,6716,6717,13086,74741) and for up to 40 months in patients with advanced cancer (10900,17102). ...when used topically and appropriately, short-term. Shark cartilage appears to be safe when applied topically for up to 8 weeks (74729).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Shark Cartilage. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
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Below is general information about the adverse effects of the known ingredients contained in the product Shark Cartilage. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, shark cartilage is generally well tolerated.
Most Common Adverse Effects:
Orally: Constipation, dizziness, dyspepsia, erythema, fatigue, hypotension, nausea, taste disturbance, and vomiting.
Serious Adverse Effects (Rare):
Orally: Altered consciousness, decreased motor strength, decreased sensation, generalized weakness, hepatitis, hyperglycemia, hypoglycemia, and peripheral edema.
Cardiovascular ...Orally, shark cartilage can cause hypotension and peripheral edema (2014,2015,6716,10900).
Endocrine ...Orally, shark cartilage can cause hyperglycemia, hypoglycemia, and hypercalcemia (2014,2015,6716,10900,74724).
Gastrointestinal ...Orally, shark cartilage can cause taste disturbances, nausea, vomiting, dyspepsia, constipation, cramping, and bloating (2014,2015,6716,10900,74724,74730,74731).
Hepatic ...Orally, shark cartilage can cause acute hepatitis, with symptoms including low-grade fever, jaundice, yellowing of the eyes, right upper quadrant tenderness, and elevated liver enzymes (2012).
Musculoskeletal ...Orally, shark cartilage can cause decreased motor strength, generalized weakness, and decreased performance (2014,2015,6716,10900).
Neurologic/CNS ...Orally, shark cartilage can cause dizziness, altered consciousness, decreased sensation, and fatigue (2014,2015,6716,10900,74725).
