Each capsule contains: L- Malic Acid 500 mg. Other Ingredients: Vegetable Capsule.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
Below is general information about the effectiveness of the known ingredients contained in the product Malic Acid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Alpha hydroxy acids represent a group of natural chemicals that are used alone or in combination. See specific monographs for effectiveness information.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Malic Acid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Some alpha hydroxy acids are used topically, while others are used orally, intravaginally, or by inhalation. See specific monographs for safety information.
PREGNANCY AND LACTATION:
See specific monographs for safety information.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Malic acid has Generally Recognized as Safe (GRAS) status in the United States. Allowed maximum levels of malic acid in foods are as follows: 3.4% for nonalcoholic beverages; 3% for chewing gum; 0.8% for gelatins, puddings, and fillings; 6.9% for hard candy; 2.6% for jams and jellies; 3.5% for processed fruits and fruit juices; 3% for soft candy; and 0.7% for all other food categories (26969,95594).
POSSIBLY SAFE ...when used orally and appropriately in medicinal amounts, short-term. Malic acid 1200 mg twice daily has been used with apparent safety for up to 6 months (3262). ...when used topically on oral mucosal surfaces. Specific malic acid combination products (Xeros Dentaid, Dentaid) have been used with apparent safety in spray and lozenge formulations for up to 6 months (92211,92213,95565,104757,104778). There is insufficient reliable information available about the safety of malic acid when used topically on the skin. Historically, malic acid has been used with apparent safety in cosmetics as a pH adjuster or fragrance ingredient, and at concentrations below 2% when used in shampoo, hair styling products, or sun protection products (26868,95595,111742).
PREGNANCY AND LACTATION: LIKELY SAFE
when used orally in amounts commonly found in foods (26969,95594).
There is insufficient reliable information available about the safety of using malic acid in medicinal amounts during pregnancy or lactation.
Below is general information about the interactions of the known ingredients contained in the product Malic Acid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, malic acid might increase the risk of hypotension when taken with antihypertensive drugs.
 Details
Animal research shows that malic acid isolated from tagetes roots can reduce mean arterial blood pressure (26970).
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Below is general information about the adverse effects of the known ingredients contained in the product Malic Acid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Alpha hydroxy acids represent a group of natural chemicals, some of which can cause adverse effects. See specific monographs for safety information.
General
...Orally, malic acid seems to be well tolerated.
Topically, malic acid seems to be well tolerated when applied to oral mucosal surfaces. A thorough evaluation of safety outcomes with topical malic acid use on the skin has not been conducted.
Most Common Adverse Effects:
Topical: Eye irritation, skin irritation, and skin peeling.
Dermatologic ...Topically, malic acid may cause moderate to strong skin irritation and peeling (26968,95564,95595). In patients first patch tested with malic acid, next instructed to avoid foods containing malic or citric acid, and then challenged with foods containing high amounts of malic and citric acid, skin reactions including immediate hives and delayed contact dermatitis occurred (26968).
Gastrointestinal ...Orally, diarrhea and nausea have been reported for patients taking a specific combination product (Super Malic) containing malic acid1200 mg and magnesium 300 mg twice daily. However, it is unclear if the adverse effect is due to malic acid, since it is known that magnesium can have a laxative effect at this dose (3262).
Ocular/Otic ...Topically, malic acid might irritate the eyes, especially in formulations containing 2. 27% or more malic acid (26968,95564,95595).
