Each suppository contains: Amebia Euchroma 13:1 extract (DHE: 85.1 mg) 82.1 mg • Bletillia Striata 13.7:1 extract (DHE: 53.2 mg) 3.9 mg • Borneol 10.6 mg • Fritillaria Thunbergii Miq 13:1 extract (DHE: 53.2 mg) 3.9 mg • Magnolia officinalis 13:1 extract (DHE: 138.3 mg) 10.6 mg • Platycladus orientalis 13:1 extract (138.3 mg) 10.6 mg • Rheum Palmaturm 13.7:1 extract (DHE: 53.2 mg) 3.9 mg. Other Ingredients: Polyethylene Glycol 4000.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
Below is general information about the effectiveness of the known ingredients contained in the product Jiuhua Hemorrhoid Suppository. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
There is insufficient reliable information is available about the effectiveness of oriental arborvitae.
Below is general information about the safety of the known ingredients contained in the product Jiuhua Hemorrhoid Suppository. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used orally and appropriately, short-term. A specific product containing magnolia extract and phellodendron extract (Relora, Next Pharmaceuticals, Inc.) has been used with apparent safety in clinical trials at a dose of 250 mg two to three times daily for up to 6 weeks (14349,34246,94904). ...when used topically in a toothpaste for up to 6 months (92464).
PREGNANCY: UNSAFE
when the magnolia flower bud is used orally due to reports of uterine stimulant activity (11953).
There is insufficient reliable information available about the safety of using magnolia bark during pregnancy; avoid using.
LACTATION:
Insufficient reliable information available; avoid using.
POSSIBLY SAFE ...when the leafy twig is used orally in tea at appropriate doses, short-term. Traditionally, tea made with 6-15 grams of raw or charred leafy twig has been used with apparent safety, short-term (12).
POSSIBLY UNSAFE ...when the leafy twig is used orally long-term or at higher doses. Oriental arborvitae contains thujone. Using thujone-containing herbs long-term or at higher doses may cause harmful adverse effects, including kidney damage and convulsions (12). There is insufficient reliable information available about the safety of oriental arborvitae seed when used orally or about the safety of any part of oriental arborvitae when used topically.
PREGNANCY: POSSIBLY UNSAFE
when the leafy twig is used orally during pregnancy.
Oriental arborvitae contains thujone (12). Thujone might stimulate uterine activity (19); avoid using. There is insufficient reliable information available about the safety of oriental arborvitae when used topically during pregnancy; avoid using.
LACTATION:
There is insufficient reliable information available about the safety of oriental arborvitae when used orally or topically during lactation; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Jiuhua Hemorrhoid Suppository. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
 Details
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin (18273). This interaction has not been reported in humans.
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Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Details
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Below is general information about the adverse effects of the known ingredients contained in the product Jiuhua Hemorrhoid Suppository. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, magnolia seems to be well tolerated.
Most Common Adverse Effects:
Topically: Contact dermatitis.
Dermatologic ...Topically, magnolia bark has been associated with reports of allergic contact dermatitis (92463,92468,95030,110709). In several cases, the use of anti-aging facial creams containing magnolia bark extract was associated with allergic contact dermatitis of the face (92463,92468,95030). In one case, the use of a vaginal gel containing magnolia bark extract was associated with allergic contact dermatitis of the vulva (110709). Symptoms typically resolve with the use of topical corticosteroids and discontinuation of magnolia bark extract (95030,110709). Patch testing suggests that the magnolia bark extract constituents magnolol and honokiol are responsible for this adverse effect (110709).
Endocrine ...In a clinical trial of an oral combination product containing extracts of magnolia and phellodendron, one patient reported thyroid dysfunction (14349). However, it's not known if this side effect is related to magnolia or some other factor.
Gastrointestinal ...In a clinical trial of an oral combination product containing extracts of magnolia and phellodendron, one patient reported heartburn (14349). However, it's not known if this side effect is related to magnolia or some other factor.
Neurologic/CNS ...In a clinical trial of an oral combination product containing extracts of magnolia and phellodendron, one patient reported shaking hands and perilabial numbness. Another patient reported fatigue and headache (14349). However, it's not known if these side effects are related to magnolia or some other factor.
Psychiatric ...In a clinical trial of an oral combination product containing extracts of magnolia and phellodendron, one patient reported sexual dysfunction (14349). However, it's not known if this side effect is related to magnolia or some other factor.
General ...Orally, taking oriental arborvitae long-term or at high doses might cause adverse effects due to the thujone constituent. Thujone-containing herbs can cause restlessness, vomiting, dizziness, tremors, kidney damage, hallucinations, and convulsions when used long-term or at high doses. Thujone intoxication can cause psychoactivity similar to tetrahydrocannibinol, the active constituent in marijuana. (12).
Gastrointestinal ...Orally, thujone-containing herbs such as oriental arborvitae may cause vomiting when used long-term or at high doses (12).
Musculoskeletal ...Orally, thujone-containing herbs such as oriental arborvitae may cause tremors when used long-term or at high doses (12).
Neurologic/CNS ...Orally, thujone-containing herbs such as oriental arborvitae may cause dizziness and convulsions when used long-term or at high doses (12).
Psychiatric ...Orally, thujone-containing herbs such as oriental arborvitae may cause restlessness and hallucinations when used long-term or at high doses. Thujone intoxication can cause psychoactivity similar to tetrahydrocannibinol, the active constituent in marijuana. (12).
Renal ...Orally, thujone-containing herbs such as oriental arborvitae may cause kidney damage when used long-term or at high doses (12).
