Duboisia myoporoides 4 DH. Other Ingredients: Ethyl Alcohol.
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In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
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This is a homeopathic preparation. Homeopathy is a system of medicine established in the 19th century by a German physician named Samuel Hahnemann. Its basic principles are that "like treats like" and "potentiation through dilution." For example, in homeopathy, diarrhea would be treated with an extreme dilution of a substance that normally causes diarrhea when taken in high doses.
Practitioners of homeopathy believe that more dilute preparations are more potent. Many homeopathic preparations are so diluted that they contain little or no active ingredient. Therefore, most homeopathic products are not expected to have any pharmacological effects, drug interactions, or other harmful effects. Any beneficial effects are controversial and cannot be explained by current scientific methods.
Dilutions of 1 to 10 are designated by an "X." So a 1X dilution = 1:10, 3X=1:1000; 6X=1:1,000,000. Dilutions of 1 to 100 are designated by a "C." So a 1C dilution = 1:100; 3C = 1:1,000,000. Dilutions of 24X or 12C or more contain zero molecules of the original active ingredient.
Homeopathic products are permitted for sale in the US due to legislation passed in 1938 sponsored by a homeopathic physician who was also a Senator. The law still requires that the FDA allow the sale of products listed in the Homeopathic Pharmacopeia of the United States. However, homeopathic preparations are not held to the same safety and effectiveness standards as conventional medicines. For more information, see the Homeopathy monograph.
Below is general information about the effectiveness of the known ingredients contained in the product Duboisia Myoporoides (Drops). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of corkwood tree.
Below is general information about the safety of the known ingredients contained in the product Duboisia Myoporoides (Drops). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY UNSAFE ...when used orally. Corkwood tree leaves contain tropane alkaloids that are potent anticholinergics (6,106659). Large doses of scopolamine and related alkaloids can be fatal (6). Ingestion of corkwood tree leaves can cause tachycardia, agitation, delirium, and hallucinations, among other anticholinergic effects (106659).
PREGNANCY AND LACTATION: LIKELY UNSAFE
when used orally (6); avoid using.
Below is general information about the interactions of the known ingredients contained in the product Duboisia Myoporoides (Drops). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, corkwood tree might increase the risk of adverse anticholinergic effects when taken with anticholinergic drugs.
 Details
Corkwood tree contains the anticholinergic constituents atropine and scopolamine, and ingestion of corkwood tree leaves has been reported to cause effects consistent with anticholinergic toxicity (106659).
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Below is general information about the adverse effects of the known ingredients contained in the product Duboisia Myoporoides (Drops). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, corkwood tree leaves are generally regarded as unsafe.
Any benefits of therapy may not outweigh the risk of toxicity.
Most Common Adverse Effects:
Orally: Ingestion of corkwood leaves can cause poisoning. Symptoms of corkwood tree poisoning are consistent with anticholinergic toxicity. Predominant symptoms include agitation, delirium, dry mouth, flushing, hallucinations, mydriasis, and tachycardia.
Cardiovascular ...Orally, corkwood tree leaves can cause hypertension and tachycardia. In one case, a 22-year-old male presented with hypertension and tachycardia, among other symptoms, after ingesting 5-10 corkwood tree leaves. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains these adverse cardiovascular effects (106659).
Dermatologic ...Orally, corkwood tree leaves can cause flushing, hyperthermia, and anhidrosis. In one case, a 22-year-old male presented with flushing and hyperthermia, among other symptoms, after ingesting 5-10 corkwood tree leaves. Anhidrosis, or the inability to sweat normally, has also been observed with corkwood tree leaf use. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains these adverse dermatologic effects (106659).
Gastrointestinal ...Orally, corkwood tree leaves can cause dry mouth. In one case, a 22-year-old male presented with dry mouth, among other symptoms, after ingesting 5-10 corkwood tree leaves. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains the dry mouth reported in this case (106659).
Genitourinary ...Orally, corkwood tree leaves can cause urinary retention. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which explains reports of urinary retention associated with corkwood tree leaf use (106659).
Neurologic/CNS ...Orally, corkwood tree leaves can cause somnolence and tremor. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains these adverse neurologic effects (106659).
Ocular/Otic ...Orally, corkwood tree leaves can cause mydriasis. In one case, a 22-year-old male presented with mydriasis, among other symptoms, after ingesting 5-10 corkwood tree leaves. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains the mydriasis reported in this case (106659).
Psychiatric ...Orally, corkwood tree leaves can cause agitation, delirium, and hallucinations. In one case, a 22-year-old male presented with agitation, delirium, and visual hallucinations, among other symptoms, after ingesting 5-10 corkwood tree leaves. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains these adverse psychiatric effects (106659).
Pulmonary/Respiratory ...Orally, corkwood tree leaves can cause tachypnea. In one case, a 22-year-old male presented with tachypnea, among other symptoms, after ingesting 5-10 corkwood tree leaves. Alkaloid constituents in corkwood tree, namely scopolamine and atropine, have anticholinergic effects, which likely explains the tachypnea reported in this case (106659).
