Digesten-K by XtendLife

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Asthma. There is some evidence that consumption of vitamin C-rich citrus fruits, including kiwi and others, might improve lung function in people with asthma. Intake of citrus fruits 1-2 times per week has produced this benefit in some studies (6049,6055,6056). However, other studies have not found this benefit (6057,6058).
• Constipation. Preliminary clinical research shows that consuming two kiwi fruits daily for 4 weeks increases the number of complete spontaneous bowel movements from 2.2 to 4.4 per week, and improves bothersomeness and satisfaction, but not straining, when compared with baseline in adults with constipation (57530). The validity of this finding is limited by the lack of a comparator group.
• Hypertension. Preliminary clinical research shows that consuming three kiwi fruits daily for 8 weeks reduces 24-hour ambulatory systolic blood pressure by 3.6 mmHg and diastolic blood pressure by 1.9 mm Hg in patients with mild hypertension when compared with those consuming one apple daily (57648).
• Irritable bowel syndrome (IBS). Preliminary clinical research shows that consuming two kiwi fruits daily for 4 weeks decreases bowel transit time by approximately 8 hours and increases defecation frequency in patients with constipation-predominant IBS when compared to baseline. However, fecal volume does not appear to change (57571). Other preliminary clinical research in patients with constipation-predominant IBS shows that consuming three kiwi fruits daily for 4 weeks increases the number of complete spontaneous bowel movements per week by around 2.5 and improves symptoms of constipation and pain when compared to baseline (103293). The validity of these findings is limited by the lack of control groups. More evidence is needed to rate kiwi for these uses.

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LIKELY SAFE ...when used orally in food amounts (6). There is insufficient reliable information available about the safety of kiwi when used orally in amounts greater than those used in foods.

PREGNANCY AND LACTATION: LIKELY SAFE
when used in food amounts (6). There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid use.

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General ...Orally, kiwi fruit is generally well tolerated. Eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including dysphagia, urticaria, dermatitis, angioedema, and vomiting immediately following ingestion in some patients (6,963,57465,57496,57491,57497,57635,57636,109591). Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis (57464,57588,57593,57644). Anaphylactic reactions and kiwi allergy-induced asthma exacerbations have also been reported after eating kiwi fruit (51576,57464,57492,57497,57617,57624,57625,57635,109591,109592).
Topically, kiwi can cause contact urticaria (6). Topical application of kiwi may also cause hypersensitivity reactions, which are more common in patients who are allergic to latex (6197,7853).

Dermatologic ...Orally, eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including urticaria, dermatitis, and angioedema in some patients (6,963,57465,57496,57491,57497,57635,57636,109591,109592).
Topically, kiwi can cause contact urticaria (6). Topical application of kiwi may also cause hypersensitivity reactions, which are more common in patients who are allergic to latex (6197,7853).

Gastrointestinal ...Orally, eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, throat, and tongue, including dysphagia and vomiting immediately following ingestion in some patients (6). Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis (57464,57588,57593,57644).

Immunologic ...Eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including dysphagia, urticaria, dermatitis, angioedema, and vomiting immediately following ingestion in some patients (6,963,57465,57496,57491,57497,57635,57636,109591,109592). Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis (57464,57588,57593,57644). Anaphylactic reactions and kiwi allergy-induced asthma exacerbations have also been reported after eating kiwi fruit (51576,57464,57492,57497,57617,57624,57625,57635,109591,109592). Some observational research suggests that anaphylaxis after consuming kiwi fruit is more common when compared with other fruits, especially in children. Of 250 patients reporting to the emergency department for fruit-induced anaphylaxis, around 16% reported kiwi fruit as the culprit, followed by banana (11%) and mango (9%) (109591). Rarely, exercise may trigger an anaphylactic reaction to kiwi fruit in individuals with no history of kiwi fruit allergy (109592).
Topically, kiwi can cause contact urticaria (6). Topical application of kiwi may also cause hypersensitivity reactions, which are more common in patients who are allergic to latex (6197,7853).

Pulmonary/Respiratory ...Orally, anaphylactic reactions and kiwi allergy-induced asthma exacerbations have been reported after eating kiwi fruit (51576,57464,57492,57497,57617,57624,57625,57635,109591,109592).

(Read more about KIWI)