| Ingredients | Amount Per Serving |
|---|---|
|
(fruit & flower)
(1:8)
(Elderberry fruit & flower extract PlantPart: fruit & flower Note: 1:8 )
|
5 mL |
Grain Alcohol Note: 40%, purified Water
Below is general information about the effectiveness of the known ingredients contained in the product Full Spectrum Elderberry Fluid Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of American elder.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Full Spectrum Elderberry Fluid Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when the flower is used in amounts found in foods. The flowers have Generally Recognized as Safe (GRAS) status in the US (4912). Cooked, ripe fruit has few if any adverse effects (6).
POSSIBLY SAFE ...when flowers are used orally for medicinal purposes (12).
POSSIBLY UNSAFE ...when leaves, stems, or unripe fruit are used. All these parts contain cyanogenic glycosides (12). Limit juice consumption to avoid toxicity (6).
PREGNANCY AND LACTATION: LIKELY UNSAFE
when the leaves, stems, or unripe fruit are used (6).
There is insufficient reliable information available about the safety of the flower or cooked fruit; avoid using.
LIKELY SAFE ...when used orally in the amounts typically found in foods. Elderberry has generally recognized as safe (GRAS) status in the US (4912).
POSSIBLY SAFE ...when elderberry fruit extract is used orally, short-term. One specific elderberry fruit extract (Sambucol, Nature's Way) has been used with apparent safety for up to 5 days (5260,12235,103831); another (BerryPharma, Iprona AG) has been used with apparent safety for up to 15 days (91374). A specific elderberry fruit extract lozenge (ViraBLOC, HerbalScience) has been used with apparent safety for 2 days (17022). Other elderberry fruit extracts have been used with apparent safety for up to 12 weeks (21141,21142).
POSSIBLY UNSAFE ...when elder tree leaves and stems, or unripe or uncooked elderberries, are consumed. The unripe green fruit, as well as the leaves and stems of the elder tree, contain a cyanide-producing chemical, which can cause serious toxicity (17020,17021,21143,21144,91374). Cooking eliminates the toxin.
CHILDREN: LIKELY SAFE
when consumed in the amounts typically found in foods.
CHILDREN: POSSIBLY SAFE
when used orally for up to 3 days.
A specific fruit extract (Sambucol, Nature's Way) has been used in doses of 15 mL twice daily for 3 days in children 5 years and older (5260,103831).
CHILDREN: POSSIBLY UNSAFE
when unripe or uncooked elderberries are consumed.
The unripe green fruit, as well as the leaves and stems of the elder tree, contain a cyanide-producing chemical , which can cause serious toxicity (17020,17021,21143,21144,91374). Cooking eliminates the toxin.
PREGNANCY AND LACTATION: LIKELY SAFE
when consumed in the amounts typically found in foods.
There is insufficient reliable information available about the safety of elderberry when used for medicinal purposes; avoid using in amounts greater than those found in foods.
Below is general information about the interactions of the known ingredients contained in the product Full Spectrum Elderberry Fluid Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is preliminary evidence that American elder can inhibit the cytochrome P450 3A4 (CYP3A4) enzymes (6450). Theoretically, American elder might increase levels of drugs metabolized by CYP3A4; however, this interaction has not been reported in humans. Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and numerous others. Use American elder cautiously or avoid in patients taking these drugs.
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American elder is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, American elder might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
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Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
 Details
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor (10796).
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Below is general information about the adverse effects of the known ingredients contained in the product Full Spectrum Elderberry Fluid Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, ingesting several glasses of American elderberry juice can cause nausea, vomiting, weakness, dizziness, numbness, and stupor (6).
General
...Orally, elderberry extracts prepared from ripe fruit seem to be well tolerated.
Most Common Adverse Effects:
Orally: When adverse effects occur, they are likely due to ingestion of raw and unripe elderberries, or seeds, leaves, and other plant parts. Due to cyanogenic glycosides, these may cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and stupor. Cooking eliminates the toxin.
Gastrointestinal
...Orally, nausea and vomiting have been reported after consuming a specific elderberry and echinacea product
Vogel Bioforce AG) (95650). However, it is unclear if this was due to the elderberry or Echinacea contained in the product.
Raw and unripe elderberries, and the seeds, leaves, and other elder tree parts might cause nausea, vomiting, or severe diarrhea due to cyanogenic glycosides (17020,17021). Cooking eliminates the toxin.
Hepatic ...In one case report, a 60-year-old female with underlying autoimmune disease presented with autoimmune hepatitis after taking elderberry at an unknown dose for several years. The patient presented with nausea, jaundice, abdominal pain, and abdominal distention. Liver function tests returned to baseline 4 weeks after initiating treatment with prednisone 40 mg daily and discontinuing elderberry (110123).
Immunologic ...Elder tree pollen might cause an allergic reaction characterized by rhinitis and dyspnea in some patients who are allergic to grass pollen. These patients might also experience an allergic reaction to elderberry extracts (11095).
Neurologic/CNS ...Raw and unripe elderberries might cause weakness, dizziness, numbness, and stupor due to cyanogenic glycosides (17020,17021). Cooking eliminates the toxin.
