Active Ingredients: Aethusa cynapium 4X • Aletris Farinosa 4X • Cerium Oxalicum (oxalate of cerium) 6X • Cucurbita Pepo Semen 3X • Gossypium herbaceum 3X • Kali Tartaricum (tartrate of potash) 8X • Natrum muriaticum (sodium chloride) 3X • Symphoricarpus Racemosus (snowberry) 3X • Veratrum album 4X. Inactive Ingredients: Lactose Based Tablets, Potato Starch, Calcium Behenate.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
This product is now known as Travel Sickness.
This is a homeopathic preparation. Homeopathy is a system of medicine established in the 19th century by a German physician named Samuel Hahnemann. Its basic principles are that "like treats like" and "potentiation through dilution." For example, in homeopathy, diarrhea would be treated with an extreme dilution of a substance that normally causes diarrhea when taken in high doses.
Practitioners of homeopathy believe that more dilute preparations are more potent. Many homeopathic preparations are so diluted that they contain little or no active ingredient. Therefore, most homeopathic products are not expected to have any pharmacological effects, drug interactions, or other harmful effects. Any beneficial effects are controversial and cannot be explained by current scientific methods.
Dilutions of 1 to 10 are designated by an "X." So a 1X dilution = 1:10, 3X=1:1000; 6X=1:1,000,000. Dilutions of 1 to 100 are designated by a "C." So a 1C dilution = 1:100; 3C = 1:1,000,000. Dilutions of 24X or 12C or more contain zero molecules of the original active ingredient.
Homeopathic products are permitted for sale in the US due to legislation passed in 1938 sponsored by a homeopathic physician who was also a Senator. The law still requires that the FDA allow the sale of products listed in the Homeopathic Pharmacopeia of the United States. However, homeopathic preparations are not held to the same safety and effectiveness standards as conventional medicines. For more information, see the Homeopathy monograph.
Below is general information about the effectiveness of the known ingredients contained in the product Symphoricarpus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of aletris.
There is insufficient reliable information available about the effectiveness of fool's parsley.
INSUFFICIENT RELIABLE EVIDENCE to RATE
There is insufficient reliable information available about the effectiveness of white hellebore.
Below is general information about the safety of the known ingredients contained in the product Symphoricarpus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the safety of aletris.
PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when used orally due to the possibility that aletris contains components that cause estrogenic activity (11) and oxytocin (Pitocin) antagonism (12); avoid using.
LIKELY UNSAFE ...when used orally. Fool's parsley is considered poisonous and has been associated with serious, potentially life-threatening, poisonings (18).
PREGNANCY AND LACTATION: LIKELY UNSAFE
when used orally due to potential for poisoning (18).
LIKELY SAFE ...when used orally and appropriately in amounts commonly found in foods.
POSSIBLY SAFE ...when the seed or seed oil is used orally and appropriately in medicinal amounts, short-term. Pumpkin seed has been used with apparent safety in a dose of up to 10 grams daily for up to 12 months (92383). Pumpkin seed oil has been used with apparent safety in a dose of up to 400 mg daily for up to 6 months (92378). There is insufficient reliable information available about the safety of pumpkin seed oil when used topically.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using amounts greater than those found in food.
LIKELY UNSAFE ...when used orally. All plant parts are considered toxic (6). Between 10-20 mg of alkaloids (1-2 grams of rhizome/root) are lethal (6,18). ...when used topically. Toxic alkaloids can be absorbed through intact skin (6,18).
PREGNANCY: LIKELY UNSAFE
when used orally or topically because it could be teratogenic (6); avoid using.
LACTATION: LIKELY UNSAFE
when used orally or topically (6); avoid using.
Below is general information about the interactions of the known ingredients contained in the product Symphoricarpus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of antacids (19).
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Aletris might have estrogenic effects (6). Theoretically, use of aletris with estrogens might increase the risk for additive adverse effects.
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Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of H2-blockers (19). The H2 blockers include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid).
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Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of PPIs (19). PPIs include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).
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Pumpkin might reduce excretion and increase levels of lithium.
Details
Pumpkin is thought to have diuretic properties (92383). Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
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Below is general information about the adverse effects of the known ingredients contained in the product Symphoricarpus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...There is currently a limited amount of information available about the adverse effects of aletris. Orally, aletris has been reported to cause colic, stupefaction, and vertigo (6).
Gastrointestinal ...Orally, small doses of aletris have been reported to cause colic (6).
Neurologic/CNS ...Orally, small doses of aletris have been reported to cause stupefaction and vertigo (6).
General ...There is currently a limited amount of information on the adverse effects of fool's parsley. There are reports that fool's parsley, when taken orally, caused deaths when it was mistaken for garden parsley. However, there is some evidence that the plant responsible for these deaths was actually spotted hemlock (18). Until more is known, caution is warranted.
General
...Orally, pumpkin products are generally well tolerated.
Most Common Adverse Effects:
Orally: Abdominal discomfort, diarrhea, nausea, and vomiting.
Serious Adverse Effects (Rare):
Orally: Anaphylaxis.
Dermatologic ...There are two case reports of adult females developing substantial transient hair loss 1-3 weeks after consumption of a meal containing either bitter-tasting pumpkin or undefined squash. This adverse effect was attributed to a high concentration of cucurbitacin, which is commonly found in wild pumpkins (104535).
Gastrointestinal ...Orally, pumpkin seed oil has been reported to cause mild abdominal discomfort in clinical trials (5093,92378). There are also two case reports of adults developing severe nausea, vomiting, and diarrhea following consumption of a meal containing either bitter-tasting pumpkin or undefined squash. These adverse effects were attributed to a high concentration of cucurbitacin, which is commonly found in wild pumpkins (104535).
Immunologic
...Orally, pumpkin seed oil and pumpkin pulp have been reported to cause anaphylactic reactions in children and adults.
A case review highlights 4 cases of anaphylaxis in children (3 from pumpkin pulp, 1 from pumpkin seeds), and 7 cases in adults (1 from pumpkin flesh, 6 from pumpkin seeds). Symptoms of anaphylaxis include urticaria, angioedema of the lips or face, dyspnea, dysphagia, and oropharyngeal itching and swelling. A case report describes a 2-year-old male presenting with urticaria, swollen lips, and increased dyspnea 10 minutes after ingesting pumpkin seeds. The patient was found to have elevated allergen-specific immunoglobulin E (IgE) and a positive skin-prick test for pumpkin seeds. Symptoms resolved after treatment with epinephrine, systemic glucocorticoids, salbuterol, and antihistamines (107843).
There may also be concern for allergic reaction due to inhalation or topical exposure. One case report describes an 8-year-old child developing anaphylaxis while carving a pumpkin; another highlights that inhalation of pumpkin seed flour may have potentiated anaphylaxis in 3 individuals following the ingestion of pumpkin seeds (107843). Further research is necessary to assess the relationship between anaphylaxis and route of administration.
General
...Orally and topically, white hellebore is generally regarded as unsafe for any use.
Any benefits of therapy do not outweigh the risk of toxicity.
Most Common Adverse Effects:
Orally: Abdominal pain, blurred vision, bradycardia, confusion, headache, hypotension, nausea, muscle weakness, vomiting.
Topically: Skin irritation.
Serious Adverse Effects (Rare):
Orally: Arrythmias, blindness, gastric erosion, loss of consciousness, paralysis, respiratory depression, seizures, severe bradycardia, severe hypotension, shock
Cardiovascular ...Orally, white hellebore can cause bradycardia and hypotension. Large doses of white hellebore can cause more severe bradycardia and hypotension and even cardiac arrythmias (6,553,95892,95893,101431,109467).
Dermatologic ...Topically, white hellebore can cause skin irritation (18).
Gastrointestinal ...Orally, white hellebore is toxic and usually causes nausea, vomiting, and abdominal pain. Symptoms occur 15-30 minutes after ingestion (553,95893,101431,109467). White hellebore can also cause a burning sensation in the upper abdomen, salivation, and gastric erosion (6,553).
Musculoskeletal ...Orally, white hellebore is toxic and can cause muscle weakness. In large doses it can cause paralysis (101431).
Neurologic/CNS ...Orally, white hellebore is toxic and can cause vertigo, confusion, numbness, headache, paresthesia, seizures, loss of consciousness, and shock (553,101431,95893).
Ocular/Otic ...Orally, white hellebore is toxic and can cause blurred and dim vision, and transitional blindness in case reports (101431,95893).
Pulmonary/Respiratory
...Orally, white hellebore is toxic and can cause respiratory depression in large doses (6,101431).
By inhalation, the powdered root induces violent sneezing and runny nose (6).