Copyright © 2021 Natural Medicines (
February 2013

FDA: Undeclared Drugs in Weight Loss Supplements

The U.S. Food and Drug Administration (FDA) recently issued a consumer warning for several weight loss supplements manufactured by Globe All Wellness, LLC.

The FDA discovered that the weight loss products, falsely marketed as supplements, contained sibutramine, making them unapproved drugs. Sibutramine is a main ingredient in Meridia, a drug for obesity. Sibutramine is a type of central nervous system (CNS) stimulant, also called psychomotor stimulants or uppers. CNS stimulants are a class of drugs that speed up physical and mental processes.

Sibutramine can cause increase blood pressure or pulse rate, which may cause significant risks to patients with heart disease, heart failure, abnormal heart beat rates, or stroke. Sibutramine may also interact adversely with prescription drugs.

The seized products containing sibutramine include SlimXtreme, SlimXtreme Gold, SlimPlus, SlimLee, GelSlim, SlimDrops and Colonew. Individuals taking these products should report any negative side effects to their healthcare provider and the FDA's MedWatch Safety Information and Adverse Event Reporting Program.

For more information about integrative therapies for weight loss, please visit Natural Standard's Comparative Effectiveness Database.


  1. Natural Standard: The Authority on Integrative Medicine. 
  2. US Food and Drug Administration.

The information in this brief report is intended for informational purposes only, and is meant to help users better understand health concerns. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions. Copyright © 2021 Natural Medicines Inc. Commercial distribution or reproduction prohibited. Natural Medicines is the leading provider of high-quality, evidence-based, clinically-relevant information on natural medicine, dietary supplements, herbs, vitamins, minerals, functional foods, diets, complementary practices, CAM modalities, exercises and medical conditions. Monograph sections include interactions with herbs, drugs, foods and labs, contraindications, depletions, dosing, toxicology, adverse effects, pregnancy and lactation data, synonyms, safety and effectiveness.