News

Copyright © 2017 Natural Medicines (www.naturalmedicines.com)
July 2015

Adverse Effects of St. John's Wort Similar to Fluoxetine

A recent study comparing adverse effects reports for St. John's Wort to those for fluoxetine found that the side effects of the natural medicine were similar to those of the prescription drug. Fluoxetine and St. John's wort affected the body systems similarly, particularly the central nervous system, and caused anxiety, dizziness, nausea, panic attacks, as well as increases in blood pressure. St. John's wort is commonly used as a natural alternative to drugs for depression.

References

  1. Hoban CL, Byard RW, Musgrave IF. A comparison of patterns of spontaneous adverse drug reaction reporting with St. John's Wort and fluoxetine during the period 2000-2013. Clin Exp Pharmacol Physiol. 2015 Jul;42(7):747-51.

The information in this brief report is intended for informational purposes only, and is meant to help users better understand health concerns. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions. Copyright © 2017 Natural Medicines Inc. Commercial distribution or reproduction prohibited. Natural Medicines is the leading provider of high-quality, evidence-based, clinically-relevant information on natural medicine, dietary supplements, herbs, vitamins, minerals, functional foods, diets, complementary practices, CAM modalities, exercises and medical conditions. Monograph sections include interactions with herbs, drugs, foods and labs, contraindications, depletions, dosing, toxicology, adverse effects, pregnancy and lactation data, synonyms, safety and effectiveness.