Results from the Physicians' Health Study I, including data on 18,530 men, found no significant link between multivitamin use over a 12-year period and cardiovascular events. However, self-reported data showed that men who consistently took a daily multivitamin for 20 years or longer had a 44% reduced risk of a major cardiovascular event, such as heart attack or stroke. The kinds and amounts of nutrients in multivitamins vary widely, but typically include vitamins A, C, D, E and K; biotin; B vitamins; folic acid; and minerals.
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