January 2017

Glucosamine & Chondroitin Linked to Colorectal Cancer Risk

New population research shows that taking both glucosamine and chondroitin supplements is associated a reduced risk of developing colorectal cancer. Data from two cohort studies evaluated glucosamine and chondroitin use from 2002 to 2010. One study included female nurses 30-55 years-old, and the second included male health professionals 40-75 years-old. Accounting for other factors, including sex, BMI and physical activity, taking both supplements regularly was linked to a 23% reduced risk of developing colorectal cancer. Use of either chondroitin or glucosamine alone was not associated with a significantly reduced risk of colorectal cancer. Study authors hypothesized that the anti-inflammatory effects of glucosamine and chondroitin might reduce cancer risk.


  1. Kantor ED, Zhang X, Wu K, et al. Use of glucosamine and chondroitin supplements in relation to risk of colorectal cancer: Results from the Nurses' Health Study and Health Professionals follow-up study. Int J Cancer. 2016;139(9):1949-57.

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