A new clinical study shows that taking glucosamine sulfate 750 mg three times daily for 3 months can increase intraocular pressure (IOP) in some people. About 34% of patients who took this dose of glucosamine sulfate experienced a clinically meaningful increase in IOP compared to only about 13% of patients taking placebo. To be on the safe side, patients with severe glaucoma should avoid glucosamine. Patients with mild-to-moderate glaucoma should be monitored for changes in IOP if they start taking glucosamine. Recommend checking IOP within 3 months of starting glucosamine. If IOP increases, glucosamine may need to be discontinued. For more details about glucosamine, review our complete scientific monograph.
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