News

Copyright © 2022 Natural Medicines (www.naturalmedicines.com)
May 2022

Glucosamine and Chondroitin Linked to Liver Problems?

Glucosamine and chondroitin have been linked to liver damage in the past. Is this still a concern?

Not likely. While combinations of glucosamine and chondroitin have been linked with acute liver injury in several case reports, in most cases it’s not clear if the reported adverse events were directly related to glucosamine, chondroitin, the combination, or other ingredients. Additionally, many subsequent studies have found that liver injury isn’t among the most common or concerning side effects for these products.

If patients ask about safety concerns related to glucosamine or chondroitin, explain that the most common side effects aren’t related to the liver at all. Rather, they both tend to be associated with stomach complaints, such as bloating and diarrhea. 

To learn more, check out our recently launched CE course: Understanding Glucosamine & Chondroitin.

The information in this brief report is intended for informational purposes only, and is meant to help users better understand health concerns. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions. Copyright © 2022 Natural Medicines Inc. Commercial distribution or reproduction prohibited. Natural Medicines is the leading provider of high-quality, evidence-based, clinically-relevant information on natural medicine, dietary supplements, herbs, vitamins, minerals, functional foods, diets, complementary practices, CAM modalities, exercises and medical conditions. Monograph sections include interactions with herbs, drugs, foods and labs, contraindications, depletions, dosing, toxicology, adverse effects, pregnancy and lactation data, synonyms, safety and effectiveness.