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December 2024

NatMed Condition Series: Dyspepsia

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We all overindulge during the holidays. Among the many products promoted to help with indigestion, there are a few ingredients worth trying.

Let’s start with turmeric. Clinical research shows that taking turmeric 500 mg four times daily for 7 days can relieve symptoms of indigestion in 64% more patients than taking placebo. There’s also evidence that curcumin, the main constituent in turmeric, has effects similar to omeprazole in reducing indigestion severity – although it doesn’t offer additional benefits when taken together with omeprazole. It’s likely safe when used appropriately, short-term. But advise patients with existing liver conditions to steer clear, due to several case reports of liver damage.

Artichoke might also help. Taking artichoke leaf extract 640 mg by mouth three times daily improves symptoms and quality of life in people with mild dyspepsia. Its choleretic effects, or ability to stimulate bile flow, is believed to be responsible for its benefits in this condition. And it seems to be well-tolerated – artichoke extract has been used safely at doses up to 3200 mg by mouth daily for up to 12 weeks.

Lastly, peppermint is good for more than just candy canes. Some clinical research shows that taking combination products containing peppermint and caraway oil improves quality of life and reduces symptoms of indigestion, including pain and mild stomach spasms. But it’s unclear if taking peppermint or caraway on their own will help. It’s generally well-tolerated if patients want to give it a try. Suggest looking for products containing peppermint oil 90 mg and caraway oil 50 mg – this is similar to products used in clinical research.

Review our Comparative Effectiveness chart for details on other therapies that might help.

The information in this brief report is intended for informational purposes only, and is meant to help users better understand health concerns. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions. Copyright © 2024 NatMed. Commercial distribution or reproduction prohibited. NatMed is the leading provider of high-quality, evidence-based, clinically-relevant information on natural medicine, dietary supplements, herbs, vitamins, minerals, functional foods, diets, complementary practices, CAM modalities, exercises and medical conditions. Monograph sections include interactions with herbs, drugs, foods and labs, contraindications, depletions, dosing, toxicology, adverse effects, pregnancy and lactation data, synonyms, safety and effectiveness.