August 2015

CLA Supplement Linked to Hepatitis Case

In a recent case report, a 26 year-old woman who had recently lost 50 pounds was admitted to the hospital with stomach pain, nausea, and vomiting. She had started taking conjugated linoleic acid (CLA) supplements, which are often used to reduce body fat, one week prior. She was ultimately diagnosed with the first case of hepatitis associated with CLA supplement use in the United States. This is only the third documented case worldwide. For more information about the potential risks associated with CLA use, please visit our complete monograph.


  1. Bilal M, Patel Y, Burkitt M, et al. Linoleic Acid Induced Acute Hepatitis: A Case Report and Review of the Literature. Case Reports Hepatol. 2015;2015:807354.

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