August 2015

Omega-3s Do Not Benefit Mental Function in Elderly

New research from the Age-Related Eye Disease Study 2 (AREDS2) found that supplementation with omega-3 fatty acids alone, lutein and zeaxanthin alone, or omega-3 fatty acids plus lutein and zeaxanthin has no benefits on mental function in older people with age-related macular degeneration. In addition to annual eye exams, study participants from 82 academic and community medical centers were given several mental function tests over the course of 5 years. The results show no difference in mental function between those who received any supplements versus those on placebo.


  1. Chew EY, Clemons TE, Agrón E, et al. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. JAMA. 2015 Aug 25;314(8):791-801.

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