June 2015

Nicotinamide Reduces Skin Cancer Risk

New research shows that taking 500 mg of nicotinamide (vitamin B3) by mouth twice daily for one year reduces the risk of developing non-melanoma skin cancer in people who have already had common skin cancers such as basal cell carcinoma and squamous cell carcinoma. Nicotinamide might be beneficial for people who are at high risk of developing common skin cancers, particularly because it is very accessible and inexpensive. It does not appear to reduce melanoma skin cancer risk.

For more information about nicotinamide (vitamin B3), view our complete scientific monograph.


  1. Martin AJ, Chen A, Choy B, et al. Oral nicotinamide to reduce actinic cancer: A phase 3 double-blind randomized controlled trial. J Clin Oncol 33, 2015 (suppl; abstr 9000)

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