April 2016

Banned Stimulant Oxilofrine Found in Many Weight Loss Supplements

According to a new study, a banned pharmaceutical stimulant called oxilofrine was found in over 50% of tested supplements that listed methylsynephrine on the product label. Oxilofrine is a pharmaceutical drug developed in Europe to stimulate the heart. It has never been approved for use as a prescription drug or dietary supplement ingredient in the United States.

Of the 27 supplement brands tested, 14 tested positive for oxilofrine. Among the products with the highest quantities were Hyperdrive 3.0+ by ALR Industries Inc and Fastin by Hi-Tech Pharmaceuticals. Six of the tested products contained pharmaceutical doses or greater amounts of the stimulant. The authors noted that if consumers followed the instructions provided on the product labels, they could potentially take up to 250 mg of oxilofrine daily.


  1. Cohen PA, Avula B, Venhuis B, et al. Pharmaceutical doses of the banned stimulant oxilofrine found in dietary supplements sold in the USA. Drug Test Anal. 2016 Apr 7.

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