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Miyajima, A., Nakashima, J., Tachibana, M., Nakamura, K., Hayakawa, M., and Murai, M. N-acetylcysteine modifies cis-dichlorodiammineplatinum-induced effects in bladder cancer cells. Jpn J Cancer Res 1999;90(5):565-570. View abstract.

Jiang, B., Haverty, M., and Brecher, P. N-acetyl-L-cysteine enhances interleukin-1beta-induced nitric oxide synthase expression. Hypertension 1999;34(4 Pt 1):574-579. View abstract.

Ventura, P., Panini, R., Pasini, M. C., Scarpetta, G., and Salvioli, G. N -Acetyl-cysteine reduces homocysteine plasma levels after single intravenous administration by increasing thiols urinary excretion. Pharmacol.Res. 1999;40(4):345-350. View abstract.

Buckley, N. A., Whyte, I. M., O'Connell, D. L., and Dawson, A. H. Activated charcoal reduces the need for N-acetylcysteine treatment after acetaminophen (paracetamol) overdose. J Toxicol.Clin Toxicol. 1999;37(6):753-757. View abstract.

Buckley, N. A., Whyte, I. M., O'Connell, D. L., and Dawson, A. H. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol.Clin Toxicol. 1999;37(6):759-767. View abstract.

Woo, O. F., Mueller, P. D., Olson, K. R., Anderson, I. B., and Kim, S. Y. Shorter duration of oral N-acetylcysteine therapy for acute acetaminophen overdose. Ann Emerg.Med 2000;35(4):363-368. View abstract.

Redondo, P., Bandres, E., Solano, T., Okroujnov, I., and Garcia-Foncillas, J. Vascular endothelial growth factor (VEGF) and melanoma. N-acetylcysteine downregulates VEGF production in vitro. Cytokine 2000;12(4):374-378. View abstract.

Flescher, E. and Fingrut, O. Suppression of interleukin 2 biosynthesis by three modes of oxidative cellular stress: selective prevention by N-acetyl cysteine. Cytokine 2000;12(5):495-498. View abstract.

Grant, P. R., Black, A., Garcia, N., Prieto, J., and Garson, J. A. Combination therapy with interferon-alpha plus N-acetyl cysteine for chronic hepatitis C: a placebo controlled double-blind multicentre study. J.Med.Virol. 2000;61(4):439-442. View abstract.

Stey, C., Steurer, J., Bachmann, S., Medici, T. C., and Tramer, M. R. The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review. Eur.Respir.J 2000;16(2):253-262. View abstract.

De Rosa, S. C., Zaretsky, M. D., Dubs, J. G., Roederer, M., Anderson, M., Green, A., Mitra, D., Watanabe, N., Nakamura, H., Tjioe, I., Deresinski, S. C., Moore, W. A., Ela, S. W., Parks, D., Herzenberg, L. A., and Herzenberg, L. A. N-acetylcysteine replenishes glutathione in HIV infection. Eur.J Clin Invest 2000;30(10):915-929. View abstract.

D'Agostini, F., Balansky, R. M., Camoirano, A., and De, Flora S. Interactions between N-acetylcysteine and ascorbic acid in modulating mutagenesis and carcinogenesis. Int J Cancer 12-1-2000;88(5):702-707. View abstract.

Weinbroum, A. A., Kluger, Y., Ben, Abraham R., Shapira, I., Karchevski, E., and Rudick, V. Lung preconditioning with N-acetyl-L-cysteine prevents reperfusion injury after liver no flow-reflow: a dose-response study. Transplantation 1-27-2001;71(2):300-306. View abstract.

Neri, S., Ierna, D., Antoci, S., Campanile, E., D'Amico, R. A., and Noto, R. Association of alpha-interferon and acetyl cysteine in patients with chronic C hepatitis. Panminerva Med 2000;42(3):187-192. View abstract.

Kusano, C., Takao, S., Noma, H., Yoh, H., Aikou, T., Okumura, H., Akiyama, S., Kawamura, M., Makino, M., and Baba, M. N-acetyl cysteine inhibits cell cycle progression in pancreatic carcinoma cells. Hum.Cell 2000;13(4):213-220. View abstract.

Tolley, D. A. and Castro, J. E. Cyclophosphamide-induced cystitis of the urinary bladder of rats and its treatment. Proc R.Soc Med 1975;68(3):169-170. View abstract.

Tandon, S. K., Prasad, S., and Singh, S. Chelation in metal intoxication: influence of cysteine or N-acetyl cysteine on the efficacy of 2,3-dimercaptopropane-1-sulphonate in the treatment of cadmium toxicity. J Appl Toxicol 2002;22(1):67-71. View abstract.

Diaz-Sandoval, L. J., Kosowsky, B. D., and Losordo, D. W. Acetylcysteine to prevent angiography-related renal tissue injury (the APART trial). Am J Cardiol. 2-1-2002;89(3):356-358. View abstract.

Van Schooten, F. J., Nia, A. B., De Flora, S., D'Agostini, F., Izzotti, A., Camoirano, A., Balm, A. J., Dallinga, J. W., Bast, A., Haenen, G. R., Van't Veer, L., Baas, P., Sakai, H., and van Zandwijk, N. Effects of oral administration of N-acetyl-L-cysteine: a multi- biomarker study in smokers. Cancer Epidemiol.Biomarkers Prev. 2002;11(2):167-175. View abstract.

Tozawa, K., Okamoto, T., Hayashi, Y., Sasaki, S., Kawai, N., and Kohri, K. N-acetyl-L-cysteine enhances chemotherapeutic effect on prostate cancer cells. Urol.Res 2002;30(1):53-58. View abstract.

Pajonk, F., Riess, K., Sommer, A., and McBride, W. H. N-acetyl-L-cysteine inhibits 26S proteasome function: implications for effects on NF-kappaB activation. Free Radic.Biol Med 3-15-2002;32(6):536-543. View abstract.

Fulghesu, A. M., Ciampelli, M., Muzj, G., Belosi, C., Selvaggi, L., Ayala, G. F., and Lanzone, A. N-acetyl-cysteine treatment improves insulin sensitivity in women with polycystic ovary syndrome. Fertil.Steril. 2002;77(6):1128-1135. View abstract.

Wijnen, M. H., Roumen, R. M., Vader, H. L., and Goris, R. J. A multiantioxidant supplementation reduces damage from ischaemia reperfusion in patients after lower torso ischaemia. A randomised trial. Eur.J Vasc.Endovasc.Surg 2002;23(6):486-490. View abstract.

Briguori, C., Manganelli, F., Scarpato, P., Elia, P. P., Golia, B., Riviezzo, G., Lepore, S., Librera, M., Villari, B., Colombo, A., and Ricciardelli, B. Acetylcysteine and contrast agent-associated nephrotoxicity. J Am Coll.Cardiol. 7-17-2002;40(2):298-303. View abstract.

Allaqaband, S., Tumuluri, R., Malik, A. M., Gupta, A., Volkert, P., Shalev, Y., and Bajwa, T. K. Prospective randomized study of N-acetylcysteine, fenoldopam, and saline for prevention of radiocontrast-induced nephropathy. Catheter.Cardiovasc.Interv. 2002;57(3):279-283. View abstract.

Durham, J. D., Caputo, C., Dokko, J., Zaharakis, T., Pahlavan, M., Keltz, J., Dutka, P., Marzo, K., Maesaka, J. K., and Fishbane, S. A randomized controlled trial of N-acetylcysteine to prevent contrast nephropathy in cardiac angiography. Kidney Int 2002;62(6):2202-2207. View abstract.

Vallero, A., Cesano, G., Pozzato, M., Garbo, R., Minelli, M., Quarello, F., and Formica, M. [Contrast nephropathy in cardiac procedures: no advantages with prophylactic use of N-acetylcysteine (NAC)]. G.Ital.Nefrol. 2002;19(5):529-533. View abstract.

Kay, J., Chow, W. H., Chan, T. M., Lo, S. K., Kwok, O. H., Yip, A., Fan, K., Lee, C. H., and Lam, W. F. Acetylcysteine for prevention of acute deterioration of renal function following elective coronary angiography and intervention: a randomized controlled trial. JAMA 2-5-2003;289(5):553-558. View abstract.

Lappas, M., Permezel, M., and Rice, G. E. N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. J.Clin.Endocrinol.Metab 2003;88(4):1723-1729. View abstract.

Molnar, Z., Szakmany, T., and Koszegi, T. Prophylactic N-acetylcysteine decreases serum CRP but not PCT levels and microalbuminuria following major abdominal surgery. A prospective, randomised, double-blinded, placebo-controlled clinical trial. Intensive Care Med 2003;29(5):749-755. View abstract.

Baker, C. S., Wragg, A., Kumar, S., De, Palma R., Baker, L. R., and Knight, C. J. A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study. J Am.Coll.Cardiol. 6-18-2003;41(12):2114-2118. View abstract.

Alsalim, W. and Fadel, M. Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Oral methionine compared with intravenous n-acetyl cysteine for paracetamol overdose. Emerg.Med.J. 2003;20(4):366-367. View abstract.

Kinter, A. L., Poli, G., and Fauci, A. S. N-acetyl-cysteine is a potent suppressor of human immunodeficiency virus transcription in persistently infected cells. Trans.Assoc.Am.Physicians 1992;105:36-43. View abstract.

Ballke, E. H., Wiersbitzky, S., Mahner, B., and Konig, A. The effect of N-acetyl-cysteine (Mucosolvin) on the transmural potential difference of the mucosa in children. Padiatr.Grenzgeb. 1992;31(2):97-101. View abstract.

Bijlmer-Iest, J. C., Baart, de la Faille, van Asbeck, B. S., van, Hattum J., van, Weelden H., Marx, J. J., and Koningsberger, J. C. Protoporphyrin photosensitivity cannot be attenuated by oral N-acetylcysteine. Photodermatol.Photoimmunol.Photomed. 1992;9(6):245-249. View abstract.

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Reynard, K., Riley, A., and Walker, B. E. Respiratory arrest after N-acetylcysteine for paracetamol overdose. Lancet 9-12-1992;340(8820):675. View abstract.

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Sheffner, A. L., Medler, E. M., JACOBS, L. W., and Sarett, H. P. THE IN VITRO REDUCTION IN VISCOSITY OF HUMAN TRACHEOBRONCHIAL SECRETIONS BY ACETYLCYSTEINE. Am Rev.Respir.Dis. 1964;90:721-729. View abstract.

BERNSTEIN, I. L. and AUSDENMOORE, R. W. IATROGENIC BRONCHOSPASM OCCURRING DURING CLINICAL TRIALS OF A NEW MUCOLYTIC AGENT, ACETYLCYSTEINE. Dis.Chest 1964;46:469-473. View abstract.

REAS, H. W. THE USE OF N-ACETYLCYSTEINE IN THE TREATMENT OF CYSTIC FIBROSIS. J Pediatr 1964;65:542-557. View abstract.

STAMM, S. J. and DOCTER, J. CLINICAL EVALUATION OF ACETYLCYSTEINE AS A MUCOLYTIC AGENT IN CYSTIC FIBROSIS. Dis.Chest 1965;47:414-420. View abstract.

MacNeill, B. D., Harding, S. A., Bazari, H., Patton, K. K., Colon-Hernadez, P., DeJoseph, D., and Jang, I. K. Prophylaxis of contrast-induced nephropathy in patients undergoing coronary angiography. Catheter.Cardiovasc.Interv. 2003;60(4):458-461. View abstract.

Efrati, S., Dishy, V., Averbukh, M., Blatt, A., Krakover, R., Weisgarten, J., Morrow, J. D., Stein, M. C., and Golik, A. The effect of N-acetylcysteine on renal function, nitric oxide, and oxidative stress after angiography. Kidney Int 2003;64(6):2182-2187. View abstract.

Ahola, T., Lapatto, R., Raivio, K. O., Selander, B., Stigson, L., Jonsson, B., Jonsbo, F., Esberg, G., Stovring, S., Kjartansson, S., Stiris, T., Lossius, K., Virkola, K., and Fellman, V. N-acetylcysteine does not prevent bronchopulmonary dysplasia in immature infants: a randomized controlled trial. J Pediatr 2003;143(6):713-719. View abstract.

Tossios, P., Bloch, W., Huebner, A., Raji, M. R., Dodos, F., Klass, O., Suedkamp, M., Kasper, S. M., Hellmich, M., and Mehlhorn, U. N-acetylcysteine prevents reactive oxygen species-mediated myocardial stress in patients undergoing cardiac surgery: results of a randomized, double-blind, placebo-controlled clinical trial. J Thorac.Cardiovasc.Surg 2003;126(5):1513-1520. View abstract.

Gunduz, H., Karabay, O., Tamer, A., Ozaras, R., Mert, A., and Tabak, O. F. N-acetyl cysteine therapy in acute viral hepatitis. World J.Gastroenterol. 2003;9(12):2698-2700. View abstract.

Kefer, J. M., Hanet, C. E., Boitte, S., Wilmotte, L., and De, Kock M. Acetylcysteine, coronary procedure and prevention of contrast-induced worsening of renal function: which benefit for which patient? Acta Cardiol. 2003;58(6):555-560. View abstract.

Eren, N., Cakir, O., Oruc, A., Kaya, Z., and Erdinc, L. Effects of N-acetylcysteine on pulmonary function in patients undergoing coronary artery bypass surgery with cardiopulmonary bypass. Perfusion 2003;18(6):345-350. View abstract.

Kleinveld, H. A., Demacker, P. N., and Stalenhoef, A. F. Failure of N-acetylcysteine to reduce low-density lipoprotein oxidizability in healthy subjects. Eur.J Clin Pharmacol 1992;43(6):639-642. View abstract.

Goldenberg, I., Shechter, M., Matetzky, S., Jonas, M., Adam, M., Pres, H., Elian, D., Agranat, O., Schwammenthal, E., and Guetta, V. Oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy following coronary angiography. A randomized controlled trial and review of the current literature. Eur.Heart J 2004;25(3):212-218. View abstract.

Sucu, N., Cinel, I., Unlu, A., Aytacoglu, B., Tamer, L., Kocak, Z., Karaca, K., Gul, A., Dikmengil, M., Atik, U., and Oral, U. N-acetylcysteine for preventing pump-induced oxidoinflammatory response during cardiopulmonary bypass. Surg Today 2004;34(3):237-242. View abstract.

Majano, P. L., Medina, J., Zubia, I., Sunyer, L., Lara-Pezzi, E., Maldonado-Rodriguez, A., Lopez-Cabrera, M., and Moreno-Otero, R. N-Acetyl-cysteine modulates inducible nitric oxide synthase gene expression in human hepatocytes. J.Hepatol. 2004;40(4):632-637. View abstract.

Agarwal, A., Munoz-Najar, U., Klueh, U., Shih, S. C., and Claffey, K. P. N-acetyl-cysteine promotes angiostatin production and vascular collapse in an orthotopic model of breast cancer. Am.J.Pathol. 2004;164(5):1683-1696. View abstract.

Fung, J. W., Szeto, C. C., Chan, W. W., Kum, L. C., Chan, A. K., Wong, J. T., Wu, E. B., Yip, G. W., Chan, J. Y., Yu, C. M., Woo, K. S., and Sanderson, J. E. Effect of N-acetylcysteine for prevention of contrast nephropathy in patients with moderate to severe renal insufficiency: a randomized trial. Am.J Kidney Dis. 2004;43(5):801-808. View abstract.

Kilic-Okman, T. and Kucuk, M. N-acetyl-cysteine treatment for polycystic ovary syndrome. Int.J.Gynaecol.Obstet. 2004;85(3):296-297. View abstract.

Ochoa, A., Pellizzon, G., Addala, S., Grines, C., Isayenko, Y., Boura, J., Rempinski, D., O'Neill, W., and Kahn, J. Abbreviated dosing of N-acetylcysteine prevents contrast-induced nephropathy after elective and urgent coronary angiography and intervention. J Interv.Cardiol. 2004;17(3):159-165. View abstract.

El, Mahmoud R., Le, Feuvre C., Le Quan Sang, K. H., Helft, G., Beygui, F., Batisse, J. P., and Metzger, J. P. [Absence of nephro-protective effect of acetylcysteine in patients with chronic renal failure investigated by coronary angiography]. Arch Mal Coeur Vaiss. 2003;96(12):1157-1161. View abstract.

Webb, J. G., Pate, G. E., Humphries, K. H., Buller, C. E., Shalansky, S., Al, Shamari A., Sutander, A., Williams, T., Fox, R. S., and Levin, A. A randomized controlled trial of intravenous N-acetylcysteine for the prevention of contrast-induced nephropathy after cardiac catheterization: lack of effect. Am.Heart J 2004;148(3):422-429. View abstract.

Peristeris, P., Clark, B. D., Gatti, S., Faggioni, R., Mantovani, A., Mengozzi, M., Orencole, S. F., Sironi, M., and Ghezzi, P. N-acetylcysteine and glutathione as inhibitors of tumor necrosis factor production. Cell Immunol. 1992;140(2):390-399. View abstract.

Huynh, H. Q., Couper, R. T., Tran, C. D., Moore, L., Kelso, R., and Butler, R. N. N-acetylcysteine, a novel treatment for Helicobacter pylori infection. Dig.Dis.Sci 2004;49(11-12):1853-1861. View abstract.

Azmus, A. D., Gottschall, C., Manica, A., Manica, J., Duro, K., Frey, M., Bulcao, L., and Lima, C. Effectiveness of acetylcysteine in prevention of contrast nephropathy. J Invasive.Cardiol. 2005;17(2):80-84. View abstract.

Rizk, A. Y., Bedaiwy, M. A., and Al Inany, H. G. N-acetyl-cysteine is a novel adjuvant to clomiphene citrate in clomiphene citrate-resistant patients with polycystic ovary syndrome. Fertil.Steril. 2005;83(2):367-370. View abstract.

Kerr, F., Dawson, A., Whyte, I. M., Buckley, N., Murray, L., Graudins, A., Chan, B., and Trudinger, B. The Australasian Clinical Toxicology Investigators Collaboration randomized trial of different loading infusion rates of N-acetylcysteine. Ann Emerg.Med 2005;45(4):402-408. View abstract.

Treitinger, A., Spada, C., Masokawa, I. Y., Verdi, J. C., Van Der Sander, Silveira M., Luis, M. C., Reis, M., Ferreira, S. I., and Abdalla, D. S. Effect of N-acetyl-L-cysteine on lymphocyte apoptosis, lymphocyte viability, TNF-alpha and IL-8 in HIV-infected patients undergoing anti-retroviral treatment. Braz.J Infect.Dis 2004;8(5):363-371. View abstract.

Decramer, M., Rutten-van, Molken M., Dekhuijzen, P. N., Troosters, T., van, Herwaarden C., Pellegrino, R., van Schayck, C. P., Olivieri, D., Del, Donno M., De, Backer W., Lankhorst, I., and Ardia, A. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet 4-30-2005;365(9470):1552-1560. View abstract.

Saricaoglu, F., Dal, D., Salman, A. E., Atay, O. A., Doral, M. N., Salman, M. A., Kilinc, K., and Aypar, U. Effect of low-dose N-acetyl-cysteine infusion on tourniquet-induced ischaemia-reperfusion injury in arthroscopic knee surgery. Acta Anaesthesiol.Scand 2005;49(6):847-851. View abstract.

Khan, A. W., Fuller, B. J., Shah, S. R., Davidson, B. R., and Rolles, K. A prospective randomized trial of N-acetyl cysteine administration during cold preservation of the donor liver for transplantation. Ann.Hepatol 2005;4(2):121-126. View abstract.

Burns, K. E., Chu, M. W., Novick, R. J., Fox, S. A., Gallo, K., Martin, C. M., Stitt, L. W., Heidenheim, A. P., Myers, M. L., and Moist, L. Perioperative N-acetylcysteine to prevent renal dysfunction in high-risk patients undergoing cabg surgery: a randomized controlled trial. JAMA 7-20-2005;294(3):342-350. View abstract.

Ng, T. M., Shurmur, S. W., Silver, M., Nissen, L. R., O'Leary, E. L., Rigmaiden, R. S., Cieciorka, M., Porter, L. L., Ineck, B. A., Kline, M. E., and Puumala, S. E. Comparison of N-acetylcysteine and fenoldopam for preventing contrast-induced nephropathy (CAFCIN). Int J Cardiol. 5-24-2006;109(3):322-328. View abstract.

Bibi, H., Seifert, B., Oullette, M., and Belik, J. Intratracheal N-acetylcysteine use in infants with chronic lung disease. Acta Paediatr. 1992;81(4):335-339. View abstract.

Fischer, U. M., Tossios, P., and Mehlhorn, U. Renal protection by radical scavenging in cardiac surgery patients. Curr Med Res Opin. 2005;21(8):1161-1164. View abstract.

Jepsen, S., Herlevsen, P., Knudsen, P., Bud, M. I., and Klausen, N. O. Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: a prospective, randomized, placebo-controlled study. Crit Care Med 1992;20(7):918-923. View abstract.

Roes, E. M., Raijmakers, M. T., Boo, T. M., Zusterzeel, P. L., Merkus, H. M., Peters, W. H., and Steegers, E. A. Oral N-acetylcysteine administration does not stabilise the process of established severe preeclampsia. Eur.J Obstet.Gynecol.Reprod.Biol 2006;127(1):61-67. View abstract.

Ayonrinde, O. T., Phelps, G. J., Hurley, J. C., and Ayonrinde, O. A. Paracetamol overdose and hepatotoxicity at a regional Australian hospital: a 4-year experience. Intern Med J 2005;35(11):655-660. View abstract.

Foschino Barbaro, M. P., Serviddio, G., Resta, O., Rollo, T., Tamborra, R., Elisiana, Carpagnano G., Vendemiale, G., and Altomare, E. Oxygen therapy at low flow causes oxidative stress in chronic obstructive pulmonary disease: Prevention by N-acetyl cysteine. Free Radic.Res 2005;39(10):1111-1118. View abstract.

Krishna, M. and Lalmuanpuii, J. Helicobacter pylori treatment. South.Med J 2005;98(11):1068. View abstract.

Gurbuz, A. K., Ozel, A. M., Ozturk, R., Yildirim, S., Yazgan, Y., and Demirturk, L. Effect of N-acetyl cysteine on Helicobacter pylori. South.Med J 2005;98(11):1095-1097. View abstract.

Fung, J. W. S. C., Chan, W., Kum, W., and et al. Can N-acetylcysteine really prevent contrast-induced nephropathy in patients with chronic renal insufficiency? A randomized study and pooled analysis. Eur Heart J 2003;24(S136) View abstract.

Sadowska, A. M., Keenoy, B., Vertongen, T., Schippers, G., Radomska-Lesniewska, D., Heytens, E., and De Backer, W. A. Effect of N-acetylcysteine on neutrophil activation markers in healthy volunteers: in vivo and in vitro study. Pharmacol Res 2006;53(3):216-225. View abstract.

Koramaz, I., Pulathan, Z., Usta, S., Karahan, S. C., Alver, A., Yaris, E., Kalyoncu, N. I., and Ozcan, F. Cardioprotective effect of cold-blood cardioplegia enriched with N-acetylcysteine during coronary artery bypass grafting. Ann Thorac.Surg 2006;81(2):613-618. View abstract.

Spiller, H. A., Winter, M. L., Klein-Schwartz, W., and Bangh, S. A. Efficacy of activated charcoal administered more than four hours after acetaminophen overdose. J Emerg.Med 2006;30(1):1-5. View abstract.

Yesilbursa, D., Serdar, A., Senturk, T., Serdar, Z., Sag, S., and Cordan, J. Effect of N-acetylcysteine on oxidative stress and ventricular function in patients with myocardial infarction. Heart Vessels 2006;21(1):33-37. View abstract.

Orhan, G., Yapici, N., Yuksel, M., Sargin, M., Senay, S., Yalcin, A. S., Aykac, Z., and Aka, S. A. Effects of N-acetylcysteine on myocardial ischemia-reperfusion injury in bypass surgery. Heart Vessels 2006;21(1):42-47. View abstract.

LaRowe, S. D., Mardikian, P., Malcolm, R., Myrick, H., Kalivas, P., McFarland, K., Saladin, M., McRae, A., and Brady, K. Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals. Am J Addict. 2006;15(1):105-110. View abstract.

Lin, P. C., Lee, M. Y., Wang, W. S., Yen, C. C., Chao, T. C., Hsiao, L. T., Yang, M. H., Chen, P. M., Lin, K. P., and Chiou, T. J. N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: preliminary data. Support.Care Cancer 2006;14(5):484-487. View abstract.

Manov, I., Motanis, H., Frumin, I., and Iancu, T. C. Hepatotoxicity of anti-inflammatory and analgesic drugs: ultrastructural aspects. Acta Pharmacol Sin. 2006;27(3):259-272. View abstract.

Sandhu, C., Belli, A. M., and Oliveira, D. B. The role of N-acetylcysteine in the prevention of contrast-induced nephrotoxicity. Cardiovasc.Intervent.Radiol. 2006;29(3):344-347. View abstract.

Macedo, E., Abdulkader, R., Castro, I., Sobrinho, A. C., Yu, L., and Vieira, J. M., Jr. Lack of protection of N-acetylcysteine (NAC) in acute renal failure related to elective aortic aneurysm repair-a randomized controlled trial. Nephrol.Dial.Transplant. 2006;21(7):1863-1869. View abstract.

Tirouvanziam, R., Conrad, C. K., Bottiglieri, T., Herzenberg, L. A., Moss, R. B., and Herzenberg, L. A. High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis. Proc Natl.Acad.Sci U.S.A 3-21-2006;103(12):4628-4633. View abstract.

Niemi, T. T., Munsterhjelm, E., Poyhia, R., Hynninen, M. S., and Salmenpera, M. T. The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. Blood Coagul.Fibrinolysis 2006;17(1):29-34. View abstract.

Pannu, N. and Tonelli, M. Strategies to reduce the risk of contrast nephropathy: an evidence-based approach. Curr Opin.Nephrol.Hypertens. 2006;15(3):285-290. View abstract.

Brok, J., Buckley, N., and Gluud, C. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database.Syst.Rev. 2006;(2):CD003328. View abstract.

Coyle, L. C., Rodriguez, A., Jeschke, R. E., Simon-Lee, A., Abbott, K. C., and Taylor, A. J. Acetylcysteine In Diabetes (AID): a randomized study of acetylcysteine for the prevention of contrast nephropathy in diabetics. Am Heart J 2006;151(5):1032-12. View abstract.

Melzer, J., Saller, R., Schapowal, A., and Brignoli, R. Systematic review of clinical data with BNO-101 (Sinupret) in the treatment of sinusitis. Forsch Komplement.Med (2006.) 2006;13(2):78-87. View abstract.

Gavish, D. and Breslow, J. L. Lipoprotein(a) reduction by N-acetylcysteine. Lancet 1-26-1991;337(8735):203-204. View abstract.

Hynninen, M. S., Niemi, T. T., Poyhia, R., Raininko, E. I., Salmenpera, M. T., Lepantalo, M. J., Railo, M. J., and Tallgren, M. K. N-acetylcysteine for the prevention of kidney injury in abdominal aortic surgery: a randomized, double-blind, placebo-controlled trial. Anesth.Analg. 2006;102(6):1638-1645. View abstract.

Lameire, N. H. Contrast-induced nephropathy--prevention and risk reduction. Nephrol.Dial.Transplant. 2006;21(6):i11-i23. View abstract.

Girardi, G. and Elias, M. M. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology 4-8-1991;67(2):155-164. View abstract.

Kramer, S., Dreisbach, L., Lockwood, J., Baldwin, K., Kopke, R., Scranton, S., and O'Leary, M. Efficacy of the antioxidant N-acetylcysteine (NAC) in protecting ears exposed to loud music. J Am Acad.Audiol. 2006;17(4):265-278. View abstract.

Meschi, M., Detrenis, S., Musini, S., Strada, E., and Savazzi, G. Facts and fallacies concerning the prevention of contrast medium-induced nephropathy. Crit Care Med 2006;34(8):2060-2068. View abstract.

Milewski, J., Rydzewska, G., Degowska, M., Kierzkiewicz, M., and Rydzewski, A. N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis. World J Gastroenterol. 6-21-2006;12(23):3751-3755. View abstract.

Pannu, N., Wiebe, N., and Tonelli, M. Prophylaxis strategies for contrast-induced nephropathy. JAMA 2006;295(23):2765-2779. View abstract.

Marenzi, G., Assanelli, E., Marana, I., Lauri, G., Campodonico, J., Grazi, M., De, Metrio M., Galli, S., Fabbiocchi, F., Montorsi, P., Veglia, F., and Bartorelli, A. L. N-acetylcysteine and contrast-induced nephropathy in primary angioplasty. N.Engl.J Med 6-29-2006;354(26):2773-2782. View abstract.

Baker, C. S., Wragg, A., Kumar, S., De, Palma R., Baker, L. R., and Knight, C. J. A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study. J Am Coll.Cardiol. 6-18-2003;41(12):2114-2118. View abstract.

Rahman, I. and Adcock, I. M. Oxidative stress and redox regulation of lung inflammation in COPD. Eur.Respir.J 2006;28(1):219-242. View abstract.

Badawy, A., Baker El, Nashar A., and El, Totongy M. Clomiphene citrate plus N-acetyl cysteine versus clomiphene citrate for augmenting ovulation in the management of unexplained infertility: a randomized double-blind controlled trial. Fertil.Steril. 2006;86(3):647-650. View abstract.

McKenna, M. J., Medved, I., Goodman, C. A., Brown, M. J., Bjorksten, A. R., Murphy, K. T., Petersen, A. C., Sostaric, S., and Gong, X. N-acetylcysteine attenuates the decline in muscle Na+,K+-pump activity and delays fatigue during prolonged exercise in humans. J Physiol 10-1-2006;576(Pt 1):279-288. View abstract.

Ristikankare, A., Kuitunen, T., Kuitunen, A., Uotila, L., Vento, A., Suojaranta-Ylinen, R., Salmenpera, M., and Poyhia, R. Lack of renoprotective effect of i.v. N-acetylcysteine in patients with chronic renal failure undergoing cardiac surgery. Br J Anaesth. 2006;97(5):611-616. View abstract.

Inoue, S., Yamamoto, I., Akieda, K., Sekiguchi, H., Otuka, H., Morita, S., Nakagawa, Y., and Inokuchi, S. [Alcohol abuse case of severe liver dysfunction induced by acetaminophen poisoning which was diagnosed as non-hepatic toxicity on admission]. Chudoku.Kenkyu 2006;19(3):265-271. View abstract.

Stacul, F., Adam, A., Becker, C. R., Davidson, C., Lameire, N., McCullough, P. A., and Tumlin, J. Strategies to reduce the risk of contrast-induced nephropathy. Am J Cardiol. 9-18-2006;98(6A):59K-77K. View abstract.

Schultz, M. J., Baas, M. C., van der Sluijs, H. P., Stamkot, G. A., and Smit, W. N-acetylcysteine and other preventive measures for contrast-induced nephropathy in the intensive care unit. Curr Med Chem. 2006;13(21):2565-2570. View abstract.

Ege, T., Eskiocak, S., Edis, M., and Duran, E. The role of N-acetylcysteine in lower extremity ischemia/reperfusions. J Cardiovasc.Surg (Torino) 2006;47(5):563-568. View abstract.

Kalebic, T., Kinter, A., Poli, G., Anderson, M. E., Meister, A., and Fauci, A. S. Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl.Acad.Sci U.S.A 2-1-1991;88(3):986-990. View abstract.

Moore, N. N., Lapsley, M., Norden, A. G., Firth, J. D., Gaunt, M. E., Varty, K., and Boyle, J. R. Does N-acetylcysteine prevent contrast-induced nephropathy during endovascular AAA repair? A randomized controlled pilot study. J Endovasc.Ther 2006;13(5):660-666. View abstract.

Soghier, L. M. and Brion, L. P. Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates. Cochrane.Database.Syst.Rev. 2006;(4):CD004869. View abstract.

Rumiris, D., Purwosunu, Y., Wibowo, N., Farina, A., and Sekizawa, A. Lower rate of preeclampsia after antioxidant supplementation in pregnant women with low antioxidant status. Hypertens.Pregnancy. 2006;25(3):241-253. View abstract.

Thaha, M., Yogiantoro, M., and Tomino, Y. Intravenous N-acetylcysteine during haemodialysis reduces the plasma concentration of homocysteine in patients with end-stage renal disease. Clin Drug Investig. 2006;26(4):195-202. View abstract.

Lawlor, D. K., Moist, L., DeRose, G., Harris, K. A., Lovell, M. B., Kribs, S. W., Elliot, J., and Forbes, T. L. Prevention of contrast-induced nephropathy in vascular surgery patients. Ann Vasc.Surg 2007;21(5):593-597. View abstract.

El-Hamamsy, I., Stevens, L. M., Carrier, M., Pellerin, M., Bouchard, D., Demers, P., Cartier, R., Page, P., and Perrault, L. P. Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trial. J Thorac.Cardiovasc.Surg 2007;133(1):7-12. View abstract.

Komisarof, J. A., Gilkey, G. M., Peters, D. M., Koudelka, C. W., Meyer, M. M., and Smith, S. M. N-acetylcysteine for patients with prolonged hypotension as prophylaxis for acute renal failure (NEPHRON). Crit Care Med 2007;35(2):435-441. View abstract.

Boesgaard, S., Aldershvile, J., and Poulsen, H. E. Preventive administration of intravenous N-acetylcysteine and development of tolerance to isosorbide dinitrate in patients with angina pectoris. Circulation 1992;85(1):143-149. View abstract.

Tolar, J., Orchard, P. J., Bjoraker, K. J., Ziegler, R. S., Shapiro, E. G., and Charnas, L. N-acetyl-L-cysteine improves outcome of advanced cerebral adrenoleukodystrophy. Bone Marrow Transplant. 2007;39(4):211-215. View abstract.

Thanopoulou, E., Baltayiannis, N., and Lykogianni, V. Nutritional aspects regarding lung cancer chemoprevention. J BUON. 2006;11(1):7-20. View abstract.

Elnashar, A., Fahmy, M., Mansour, A., and Ibrahim, K. N-acetyl cysteine vs. metformin in treatment of clomiphene citrate-resistant polycystic ovary syndrome: a prospective randomized controlled study. Fertil.Steril. 2007;88(2):406-409. View abstract.

Siriwardena, A. K., Mason, J. M., Balachandra, S., Bagul, A., Galloway, S., Formela, L., Hardman, J. G., and Jamdar, S. Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis. Gut 2007;56(10):1439-1444. View abstract.

Sutherland, E. R., Crapo, J. D., and Bowler, R. P. N-acetylcysteine and exacerbations of chronic obstructive pulmonary disease. COPD. 2006;3(4):195-202. View abstract.

Badawy, A., State, O., and Abdelgawad, S. N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial. Acta Obstet.Gynecol.Scand 2007;86(2):218-222. View abstract.

Recio-Mayoral, A., Chaparro, M., Prado, B., Cozar, R., Mendez, I., Banerjee, D., Kaski, J. C., Cubero, J., and Cruz, J. M. The reno-protective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: the RENO Study. J.Am.Coll.Cardiol. 3-27-2007;49(12):1283-1288. View abstract.

Haase, M., Haase-Fielitz, A., Bagshaw, S. M., Reade, M. C., Morgera, S., Seevenayagam, S., Matalanis, G., Buxton, B., Doolan, L., and Bellomo, R. Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients. Crit Care Med 2007;35(5):1324-1331. View abstract.

Grant, J. E., Kim, S. W., and Odlaug, B. L. N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study. Biol Psychiatry 9-15-2007;62(6):652-657. View abstract.

Al-Ghonaim, M. and Pannu, N. Prevention and treatment of contrast-induced nephropathy. Tech.Vasc.Interv.Radiol. 2006;9(2):42-49. View abstract.

di Mario, F., Cavallaro, L. G., Nouvenne, A., Stefani, N., Cavestro, G. M., Iori, V., Maino, M., Comparato, G., Fanigliulo, L., Morana, E., Pilotto, A., Martelli, L., Martelli, M., Leandro, G., and Franze, A. A curcumin-based 1-week triple therapy for eradication of Helicobacter pylori infection: something to learn from failure? Helicobacter. 2007;12(3):238-243. View abstract.

Sandhu, C., Belli, A. M., and Oliveira, D. B. The role of N-acetylcysteine in the prevention of contrast-induced nephrotoxicity. Cardiovasc.Intervent.Radiol. 2006;29(3):344-347. View abstract.

Zagler, A., Azadpour, M., Mercado, C., and Hennekens, C. H. N-acetylcysteine and contrast-induced nephropathy: a meta-analysis of 13 randomized trials. Am Heart J 2006;151(1):140-145. View abstract.

Grimble, G. K. Adverse gastrointestinal effects of arginine and related amino acids. J Nutr 2007;137(6 Suppl 2):1693S-1701S. View abstract.

LaRowe, S. D., Myrick, H., Hedden, S., Mardikian, P., Saladin, M., McRae, A., Brady, K., Kalivas, P. W., and Malcolm, R. Is cocaine desire reduced by N-acetylcysteine? Am J Psychiatry 2007;164(7):1115-1117. View abstract.

Gawenda, M., Moller, A., Wassmer, G., and Brunkwall, J. [Prophylaxis of contrast-induced nephropathy with N-acetylcysteine]. Zentralbl.Chir 2007;132(3):227-231. View abstract.

Chen, N., Aleksa, K., Woodland, C., Rieder, M., and Koren, G. Prevention of ifosfamide nephrotoxicity by N-acetylcysteine: clinical pharmacokinetic considerations. Can J Clin Pharmacol 2007;14(2):e246-e250. View abstract.

Rosner, M. H. and Okusa, M. D. Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol. 2006;1(1):19-32. View abstract.

Gass, J. T. and Olive, M. F. Glutamatergic substrates of drug addiction and alcoholism. Biochem.Pharmacol 1-1-2008;75(1):218-265. View abstract.

Poletti, P. A., Saudan, P., Platon, A., Mermillod, B., Sautter, A. M., Vermeulen, B., Sarasin, F. P., Becker, C. D., and Martin, P. Y. I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity. AJR Am J Roentgenol. 2007;189(3):687-692. View abstract.

Ozcan, E. E., Guneri, S., Akdeniz, B., Akyildiz, I. Z., Senaslan, O., Baris, N., Aslan, O., and Badak, O. Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimens for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial. Am Heart J 2007;154(3):539-544. View abstract.

Baranska-Kosakowska, A., Zakliczynski, M., Przybylski, R., and Zembala, M. Role of N-acetylcysteine on renal function in patients after orthotopic heart transplantation undergoing coronary angiography. Transplant.Proc 2007;39(9):2853-2855. View abstract.

Barreto, R. Prevention of contrast-induced nephropathy: the rational use of sodium bicarbonate. Nephrol.Nurs.J 2007;34(4):417-421. View abstract.

Sanders, K. M., Kotowicz, M. A., and Nicholson, G. C. Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study. Transl.Res 2007;150(4):215. View abstract.

Wijeysundera, D. N., Beattie, W. S., Rao, V., Granton, J. T., and Chan, C. T. N-acetylcysteine for preventing acute kidney injury in cardiac surgery patients with pre-existing moderate renal insufficiency. Can J Anaesth. 2007;54(11):872-881. View abstract.

Soltan-Sharifi, M. S., Mojtahedzadeh, M., Najafi, A., Reza, Khajavi M., Reza, Rouini M., Moradi, M., Mohammadirad, A., and Abdollahi, M. Improvement by N-acetylcysteine of acute respiratory distress syndrome through increasing intracellular glutathione, and extracellular thiol molecules and anti-oxidant power: evidence for underlying toxicological mechanisms. Hum Exp.Toxicol. 2007;26(9):697-703. View abstract.

Zoccali, C., Mallamaci, F., and Tripepi, G. It is important to lower homocysteine in dialysis patients. Semin.Dial. 2007;20(6):530-533. View abstract.

Gonzales, D. A., Norsworthy, K. J., Kern, S. J., Banks, S., Sieving, P. C., Star, R. A., Natanson, C., and Danner, R. L. A meta-analysis of N-acetylcysteine in contrast-induced nephrotoxicity: unsupervised clustering to resolve heterogeneity. BMC.Med 2007;5:32. View abstract.

Fishbane, S. N-acetylcysteine in the prevention of contrast-induced nephropathy. Clin J Am Soc Nephrol. 2008;3(1):281-287. View abstract.

Lavoie, S., Murray, M. M., Deppen, P., Knyazeva, M. G., Berk, M., Boulat, O., Bovet, P., Bush, A. I., Conus, P., Copolov, D., Fornari, E., Meuli, R., Solida, A., Vianin, P., Cuenod, M., Buclin, T., and Do, K. Q. Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients. Neuropsychopharmacology 2008;33(9):2187-2199. View abstract.

Ferreira, L. F. and Reid, M. B. Muscle-derived ROS and thiol regulation in muscle fatigue. J Appl Physiol 2008;104(3):853-860. View abstract.

Maioli, M., Toso, A., Leoncini, M., Gallopin, M., Tedeschi, D., Micheletti, C., and Bellandi, F. Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. J Am Coll.Cardiol. 8-19-2008;52(8):599-604. View abstract.

Shohrati, M., Aslani, J., Eshraghi, M., Alaedini, F., and Ghanei, M. Therapeutics effect of N-acetyl cysteine on mustard gas exposed patients: evaluating clinical aspect in patients with impaired pulmonary function test. Respir.Med 2008;102(3):443-448. View abstract.

Rahman, I. Antioxidant therapies in COPD. Int.J Chron.Obstruct.Pulmon.Dis. 2006;1(1):15-29. View abstract.

Sisillo, E., Ceriani, R., Bortone, F., Juliano, G., Salvi, L., Veglia, F., Fiorentini, C., and Marenzi, G. N-acetylcysteine for prevention of acute renal failure in patients with chronic renal insufficiency undergoing cardiac surgery: a prospective, randomized, clinical trial. Crit Care Med 2008;36(1):81-86. View abstract.

Reid, M. B. Free radicals and muscle fatigue: Of ROS, canaries, and the IOC. Free Radic.Biol Med 1-15-2008;44(2):169-179. View abstract.

Yilmaz, H., Sahin, S., Sayar, N., Tangurek, B., Yilmaz, M., Nurkalem, Z., Onturk, E., Cakmak, N., and Bolca, O. Effects of folic acid and N-acetylcysteine on plasma homocysteine levels and endothelial function in patients with coronary artery disease. Acta Cardiol. 2007;62(6):579-585. View abstract.

Ozaydin, M., Peker, O., Erdogan, D., Kapan, S., Turker, Y., Varol, E., Ozguner, F., Dogan, A., and Ibrisim, E. N-acetylcysteine for the prevention of postoperative atrial fibrillation: a prospective, randomized, placebo-controlled pilot study. Eur.Heart J 2008;29(5):625-631. View abstract.

Vats, P., Singh, V. K., Singh, S. N., and Singh, S. B. High altitude induced anorexia: effect of changes in leptin and oxidative stress levels. Nutr Neurosci. 2007;10(5-6):243-249. View abstract.

Stenstrom, D. A., Muldoon, L. L., Armijo-Medina, H., Watnick, S., Doolittle, N. D., Kaufman, J. A., Peterson, D. R., Bubalo, J., and Neuwelt, E. A. N-acetylcysteine use to prevent contrast medium-induced nephropathy: premature phase III trials. J Vasc.Interv.Radiol. 2008;19(3):309-318. View abstract.

Ivanovski, O., Nikolov, I. G., Drueke, B. T., and Massy, A. Z. Atherosclerosis and vascular calcification in uraemia - a new experimental model. Prilozi. 2007;28(2):11-24. View abstract.

Venkataraman, R. Can we prevent acute kidney injury? Crit Care Med 2008;36(4 Suppl):S166-S171. View abstract.

Barr, L. F. and Kolodner, K. N-acetylcysteine and fenoldopam protect the renal function of patients with chronic renal insufficiency undergoing cardiac surgery. Crit Care Med 2008;36(5):1427-1435. View abstract.

Berk, M., Copolov, D., Dean, O., Lu, K., Jeavons, S., Schapkaitz, I., Anderson-Hunt, M., Judd, F., Katz, F., Katz, P., Ording-Jespersen, S., Little, J., Conus, P., Cuenod, M., Do, K. Q., and Bush, A. I. N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial. Biol Psychiatry 9-1-2008;64(5):361-368. View abstract.

Guijarro, L. G., Mate, J., Gisbert, J. P., Perez-Calle, J. L., Marin-Jimenez, I., Arriaza, E., Olleros, T., Delgado, M., Castillejo, M. S., Prieto-Merino, D., Gonzalez, Lara, V, and Pena, A. S. N-acetyl-L-cysteine combined with mesalamine in the treatment of ulcerative colitis: randomized, placebo-controlled pilot study. World J Gastroenterol. 5-14-2008;14(18):2851-2857. View abstract.

Adabag, A. S., Ishani, A., Koneswaran, S., Johnson, D. J., Kelly, R. F., Ward, H. B., McFalls, E. O., Bloomfield, H. E., and Chandrashekhar, Y. Utility of N-acetylcysteine to prevent acute kidney injury after cardiac surgery: a randomized controlled trial. Am Heart J 2008;155(6):1143-1149. View abstract.

Berk, M., Copolov, D. L., Dean, O., Lu, K., Jeavons, S., Schapkaitz, I., Anderson-Hunt, M., and Bush, A. I. N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial. Biol Psychiatry 9-15-2008;64(6):468-475. View abstract.

Kuleci, S., Hanta, I., Kocabas, A., and Canacankatan, N. The effect of different treatment modalities on oxidative stress in COPD. Adv.Ther 2008;25(7):710-717. View abstract.

Ho, K. M. and Morgan, D. J. Meta-analysis of N-acetylcysteine to prevent acute renal failure after major surgery. Am J Kidney Dis. 2009;53(1):33-40. View abstract.

Peker, O., Peker, T., Erdogan, D., Ozaydin, M., Kapan, S., Sutcu, R., and Ibrisim, E. Effects of intravenous N-acetylcysteine on periprocedural myocardial injury after on-pump coronary artery by-pass grafting. J Cardiovasc.Surg (Torino) 2008;49(4):527-531. View abstract.

Maioli, M., Toso, A., Leoncini, M., Gallopin, M., Tedeschi, D., Micheletti, C., and Bellandi, F. Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. J.Am.Coll.Cardiol. 8-19-2008;52(8):599-604. View abstract.

Bridgeman, M. M., Marsden, M., MacNee, W., Flenley, D. C., and Ryle, A. P. Cysteine and glutathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine. Thorax 1991;46(1):39-42. View abstract.

Ghanei, M., Shohrati, M., Jafari, M., Ghaderi, S., Alaeddini, F., and Aslani, J. N-acetylcysteine improves the clinical conditions of mustard gas-exposed patients with normal pulmonary function test. Basic Clin Pharmacol Toxicol. 2008;103(5):428-432. View abstract.

Shahin, A. Y., Hassanin, I. M., Ismail, A. M., Kruessel, J. S., and Hirchenhain, J. Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis. Int J Gynaecol.Obstet. 2009;104(1):44-48. View abstract.

Amin, A. F., Shaaban, O. M., and Bediawy, M. A. N-acetyl cysteine for treatment of recurrent unexplained pregnancy loss. Reprod.Biomed.Online. 2008;17(5):722-726. View abstract.

Carbonell, N., Blasco, M., Sanjuan, R., Perez-Sancho, E., Sanchis, J., Insa, L., Bodi, V., Nunez, J., Garcia-Ramon, R., and Miguel, A. Intravenous N-acetylcysteine for preventing contrast-induced nephropathy: a randomised trial. Int J Cardiol. 1-31-2007;115(1):57-62. View abstract.

Kelly, M. K., Wicker, R. J., Barstow, T. J., and Harms, C. A. Effects of N-acetylcysteine on respiratory muscle fatigue during heavy exercise. Respir.Physiol Neurobiol. 1-1-2009;165(1):67-72. View abstract.

Moradi, M., Mojtahedzadeh, M., Mandegari, A., Soltan-Sharifi, M. S., Najafi, A., Khajavi, M. R., Hajibabayee, M., and Ghahremani, M. H. The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine. Respir.Med 2009;103(3):434-441. View abstract.

Santiago, F. M., Bueno, P., Olmedo, C., Muffak-Granero, K., Comino, A., Serradilla, M., Mansilla, A., Villar, J. M., Garrote, D., and Ferron, J. A. Effect of N-acetylcysteine administration on intraoperative plasma levels of interleukin-4 and interleukin-10 in liver transplant recipients. Transplant.Proc 2008;40(9):2978-2980. View abstract.

ten Dam, M. A. and Wetzels, J. F. Toxicity of contrast media: an update. Neth.J Med 2008;66(10):416-422. View abstract.

Heng, A. E., Cellarier, E., Aublet-Cuvelier, B., Decalf, V., Motreff, P., Marcaggi, X., Deteix, P., and Souweine, B. Is treatment with N-acetylcysteine to prevent contrast-induced nephropathy when using bicarbonate hydration out of date? Clin Nephrol. 2008;70(6):475-484. View abstract.

Naughton, F., Wijeysundera, D., Karkouti, K., Tait, G., and Beattie, W. S. N-acetylcysteine to reduce renal failure after cardiac surgery: a systematic review and meta-analysis. Can J Anaesth. 2008;55(12):827-835. View abstract.

Hart, A. M., Terenghi, G., and Wiberg, M. Neuronal death after peripheral nerve injury and experimental strategies for neuroprotection. Neurol.Res. 2008;30(10):999-1011. View abstract.

Safarinejad, M. R. and Safarinejad, S. Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study. J Urol. 2009;181(2):741-751. View abstract.

Renke, M., Tylicki, L., Rutkowski, P., Larczynski, W., Aleksandrowicz, E., Lysiak-Szydlowska, W., and Rutkowski, B. The effect of N-acetylcysteine on proteinuria and markers of tubular injury in non-diabetic patients with chronic kidney disease. A placebo-controlled, randomized, open, cross-over study. Kidney Blood Press Res 2008;31(6):404-410. View abstract.

Nigwekar, S. U. and Kandula, P. N-acetylcysteine in cardiovascular-surgery-associated renal failure: a meta-analysis. Ann Thorac.Surg 2009;87(1):139-147. View abstract.

Koksal, H., Rahman, A., Burma, O., Halifeoglu, I., and Bayar, M. K. The effects of low dose N-acetylcysteine (NAC) as an adjunct to cardioplegia in coronary artery bypass surgery. Anadolu.Kardiyol.Derg. 2008;8(6):437-443. View abstract.

Charunwatthana, P., Abul, Faiz M., Ruangveerayut, R., Maude, R. J., Rahman, M. R., Roberts, L. J., Moore, K., Bin, Yunus E., Hoque, M. G., Hasan, M. U., Lee, S. J., Pukrittayakamee, S., Newton, P. N., White, N. J., Day, N. P., and Dondorp, A. M. N-acetylcysteine as adjunctive treatment in severe malaria: a randomized, double-blinded placebo-controlled clinical trial. Crit Care Med 2009;37(2):516-522. View abstract.

Leung, K. S. and Cottler, L. B. Treatment of pathological gambling. Curr Opin.Psychiatry 2009;22(1):69-74. View abstract.

Dal, Negro R., Visconti, M., Trevisan, F., Bertacco, S., Micheletto, C., and Tognella, S. Erdosteine enhances airway response to salbutamol in patients with mild-to-moderate COPD. Ther Adv.Respir.Dis. 2008;2(5):271-277. View abstract.

Uys, J. D. and LaLumiere, R. T. Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS.Neurol.Disord.Drug Targets. 2008;7(5):482-491. View abstract.

Baker, W. L., Anglade, M. W., Baker, E. L., White, C. M., Kluger, J., and Coleman, C. I. Use of N-acetylcysteine to reduce post-cardiothoracic surgery complications: a meta-analysis. Eur.J Cardiothorac.Surg 2009;35(3):521-527. View abstract.

Nash, E. F., Stephenson, A., Ratjen, F., and Tullis, E. Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. Cochrane.Database.Syst.Rev. 2009;(1):CD007168. View abstract.

Rodrigues, A. J., Evora, P. R., Bassetto, S., Alves, L., Jr., Scorzoni, Filho A., Origuela, E. A., and Vicente, W. V. Blood cardioplegia with N-acetylcysteine may reduce coronary endothelial activation and myocardial oxidative stress. Heart Surg Forum 2009;12(1):E44-E48. View abstract.

Jo, S. H., Koo, B. K., Park, J. S., Kang, H. J., Kim, Y. J., Kim, H. L., Chae, I. H., Choi, D. J., Sohn, D. W., Oh, B. H., Park, Y. B., Choi, Y. S., and Kim, H. S. N-acetylcysteine versus AScorbic acid for preventing contrast-Induced nephropathy in patients with renal insufficiency undergoing coronary angiography NASPI study-a prospective randomized controlled trial. Am Heart J 2009;157(3):576-583. View abstract.

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Smilkstein, M. J., Bronstein, A. C., Linden, C., Augenstein, W. L., Kulig, K. W., and Rumack, B. H. Acetaminophen overdose: a 48-hour intravenous N-acetylcysteine treatment protocol. Ann Emerg.Med 1991;20(10):1058-1063. View abstract.

de Gussem, E. M., Snijder, R. J., Disch, F. J., Zanen, P., Westermann, C. J., and Mager, J. J. The effect of N-acetylcysteine on epistaxis and quality of life in patients with HHT: a pilot study. Rhinology 2009;47(1):85-88. View abstract.

Wijeysundera, D. N., Karkouti, K., Rao, V., Granton, J. T., Chan, C. T., Raban, R., Carroll, J., Poonawala, H., and Beattie, W. S. N-acetylcysteine is associated with increased blood loss and blood product utilization during cardiac surgery. Crit Care Med 2009;37(6):1929-1934. View abstract.

Keays, R., Harrison, P. M., Wendon, J. A., Forbes, A., Gove, C., Alexander, G. J., and Williams, R. Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial. BMJ 10-26-1991;303(6809):1026-1029. View abstract.

Harrison, P. M., Keays, R., Bray, G. P., Alexander, G. J., and Williams, R. Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. Lancet 6-30-1990;335(8705):1572-1573. View abstract.

Roederer, M., Staal, F. J., Raju, P. A., Ela, S. W., Herzenberg, L. A., and Herzenberg, L. A. Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine. Proc Natl.Acad.Sci U.S.A 1990;87(12):4884-4888. View abstract.

Parker, D., White, J. P., Paton, D., and Routledge, P. A. Safety of late acetylcysteine treatment in paracetamol poisoning. Hum Exp.Toxicol. 1990;9(1):25-27. View abstract.

Wu, J., Levy, E. M., and Black, P. H. 2-Mercaptoethanol and n-acetylcysteine enhance T cell colony formation in AIDS and ARC. Clin Exp.Immunol. 1989;77(1):7-10. View abstract.

Sjodin, K., Nilsson, E., Hallberg, A., and Tunek, A. Metabolism of N-acetyl-L-cysteine. Some structural requirements for the deacetylation and consequences for the oral bioavailability. Biochem.Pharmacol 11-15-1989;38(22):3981-3985. View abstract.

Prescott, L. F., Donovan, J. W., Jarvie, D. R., and Proudfoot, A. T. The disposition and kinetics of intravenous N-acetylcysteine in patients with paracetamol overdosage. Eur.J Clin Pharmacol 1989;37(5):501-506. View abstract.

Stafanger, G. and Koch, C. N-acetylcysteine in cystic fibrosis and Pseudomonas aeruginosa infection: clinical score, spirometry and ciliary motility. Eur.Respir.J 1989;2(3):234-237. View abstract.

Dawson, A. H., Henry, D. A., and McEwen, J. Adverse reactions to N-acetylcysteine during treatment for paracetamol poisoning. Med J Aust. 3-20-1989;150(6):329-331. View abstract.

Burgunder, J. M., Varriale, A., and Lauterburg, B. H. Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur.J Clin Pharmacol 1989;36(2):127-131. View abstract.

De, Caro L., Ghizzi, A., Costa, R., Longo, A., Ventresca, G. P., and Lodola, E. Pharmacokinetics and bioavailability of oral acetylcysteine in healthy volunteers. Arzneimittelforschung. 1989;39(3):382-386. View abstract.

Linden, M., Wieslander, E., Eklund, A., Larsson, K., and Brattsand, R. Effects of oral N-acetylcysteine on cell content and macrophage function in bronchoalveolar lavage from healthy smokers. Eur.Respir.J 1988;1(7):645-650. View abstract.

Eklund, A., Eriksson, O., Hakansson, L., Larsson, K., Ohlsson, K., Venge, P., Bergstrand, H., Bjornson, A., Brattsand, R., Glennow, C., and . Oral N-acetylcysteine reduces selected humoral markers of inflammatory cell activity in BAL fluid from healthy smokers: correlation to effects on cellular variables. Eur.Respir.J 1988;1(9):832-838. View abstract.

Oral N-acetylcysteine and exacerbation rates in patients with chronic bronchitis and severe airways obstruction. British Thoracic Society Research Committee. Thorax 1985;40(11):832-835. View abstract.

Braganza, J. M., Holmes, A. M., Morton, A. R., Stalley, L., Ku, R., and Kisher, R. Acetylcysteine to treat complications of pancreatitis. Lancet 4-19-1986;1(8486):914-915. View abstract.

Endo, A. and Watanabe, T. Analysis of protective activity of N-acetylcysteine against teratogenicity of heavy metals. Reprod.Toxicol. 1988;2(2):141-144. View abstract.

Smilkstein, M. J., Knapp, G. L., Kulig, K. W., and Rumack, B. H. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985). N.Engl.J Med 12-15-1988;319(24):1557-1562. View abstract.

Winniford, M. D., Kennedy, P. L., Wells, P. J., and Hillis, L. D. Potentiation of nitroglycerin-induced coronary dilatation by N-acetylcysteine. Circulation 1986;73(1):138-142. View abstract.

Horowitz, J. D., Henry, C. A., Syrjanen, M. L., Louis, W. J., Fish, R. D., Smith, T. W., and Antman, E. M. Combined use of nitroglycerin and N-acetylcysteine in the management of unstable angina pectoris. Circulation 1988;77(4):787-794. View abstract.

Powell, S. R. and McCay, P. B. Inhibition of doxorubicin-initiated membrane damage by N-acetylcysteine: possible mediation by a thiol-dependent, cytosolic inhibitor of lipid peroxidation. Toxicol.Appl Pharmacol 1988;96(2):175-184. View abstract.

Stafanger, G., Garne, S., Howitz, P., Morkassel, E., and Koch, C. The clinical effect and the effect on the ciliary motility of oral N-acetylcysteine in patients with cystic fibrosis and primary ciliary dyskinesia. Eur.Respir.J 1988;1(2):161-167. View abstract.

Rasmussen, J. B. and Glennow, C. Reduction in days of illness after long-term treatment with N-acetylcysteine controlled-release tablets in patients with chronic bronchitis. Eur.Respir.J 1988;1(4):351-355. View abstract.

Walters, M. T., Rubin, C. E., Keightley, S. J., Ward, C. D., and Cawley, M. I. A double-blind, cross-over, study of oral N-acetylcysteine in Sjogren's syndrome. Scand J Rheumatol.Suppl 1986;61:253-258. View abstract.

Cato, A., Goldstein, I., and Millman, M. A double-blind parallel study of acetylcysteine-isoproterenol and saline-isoproterenol in patients with chronic obstructive lung disease. J Int Med Res 1977;5(3):175-183. View abstract.

Parr, G. D. and Huitson, A. Oral Fabrol (oral N-acetyl-cysteine) in chronic bronchitis. Br.J.Dis.Chest 1987;81(4):341-348. View abstract.

Rogers, D. F., Godfrey, R. W., Majumdar, S., and Jeffery, P. K. Oral N-acetylcysteine speeds reversal of cigarette smoke-induced mucous cell hyperplasia in the rat. Exp.Lung Res 1988;14(1):19-35. View abstract.

Jensen, T., Kharazmi, A., Schiotz, P. O., Nielsen, H., Stenvang, Pedersen S., Stafanger, G., Koch, C., and Hoiby, N. Effect of oral N-acetylcysteine administration on human blood neutrophil and monocyte function. APMIS 1988;96(1):62-67. View abstract.

Olsson, B., Johansson, M., Gabrielsson, J., and Bolme, P. Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine. Eur.J Clin Pharmacol 1988;34(1):77-82. View abstract.

Kharazmi, A., Nielsen, H., and Schiotz, P. O. N-acetylcysteine inhibits human neutrophil and monocyte chemotaxis and oxidative metabolism. Int J Immunopharmacol. 1988;10(1):39-46. View abstract.

Cotgreave, I. A. and Moldeus, P. Methodologies for the analysis of reduced and oxidized N-acetylcysteine in biological systems. Biopharm.Drug Dispos. 1987;8(4):365-375. View abstract.

Rogers, D. F. and Jeffery, P. K. Inhibition by oral N-acetylcysteine of cigarette smoke-induced "bronchitis" in the rat. Exp.Lung Res 1986;10(3):267-283. View abstract.

Wilpart, M., Speder, A., and Roberfroid, M. Anti-initiation activity of N-acetylcysteine in experimental colonic carcinogenesis. Cancer Lett 1986;31(3):319-324. View abstract.

Borgstrom, L., Kagedal, B., and Paulsen, O. Pharmacokinetics of N-acetylcysteine in man. Eur.J Clin Pharmacol 1986;31(2):217-222. View abstract.

Millar, A. B., Pavia, D., Agnew, J. E., Lopez-Vidriero, M. T., Lauque, D., and Clarke, S. W. Effect of oral N-acetylcysteine on mucus clearance. Br J Dis.Chest 1985;79(3):262-266. View abstract.

Ratjen, F., Wonne, R., Posselt, H. G., Stover, B., Hofmann, D., and Bender, S. W. A double-blind placebo controlled trial with oral ambroxol and N-acetylcysteine for mucolytic treatment in cystic fibrosis. Eur.J Pediatr 1985;144(4):374-378. View abstract.

Bowles, W. H. and Goral, V. Clinical trial of the anti-plaque activity of a mucolytic agent, N-Acetyl Cysteine. Dent.Hyg.(Chic.) 1985;59(10):454-456. View abstract.

Verstraeten, J. M. Mucolytic treatment in chronic obstructive pulmonary disease. Double-blind comparative clinical trial with N-acetylcysteine, bromhexine and placebo. Acta Tuberc.Pneumol.Belg. 1979;70(1):71-80. View abstract.

Pratt, S. and Ioannides, C. Mechanism of the protective action of n-acetylcysteine and methionine against paracetamol toxicity in the hamster. Arch Toxicol. 1985;57(3):173-177. View abstract.

Grater, W. C. and Cato, A. Double-blind study of acetylcysteine-isoproterenol and saline-isoproterenol in non-hospitalized patients with asthma. Curr Ther Res Clin Exp. 1973;15(9):660-671. View abstract.

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Gurtoo, H. L., Marinello, A. J., Berrigan, M. J., Bansal, S. K., Paul, B., Pavelic, Z. P., and Struck, R. F. Effect of thiols on toxicity and carcinostatic activity of cyclophosphamide. Semin.Oncol 1983;10(1 Suppl 1):35-45. View abstract.

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Unverferth, B. J., Magorien, R. D., Balcerzak, S. P., Leier, C. V., and Unverferth, D. V. Early changes in human myocardial nuclei after doxorubicin. Cancer 7-15-1983;52(2):215-221. View abstract.

Stephan, U., Bowing, B., Goering, U., Wiesemann, H. G., Reinhardt, M., Hirche, H., and Brandt, H. Acetylcysteine in the oral mucolytic treatment of cystic fibrosis. Eur.J Respir.Dis.Suppl 1980;111:127-131. View abstract.

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Morgan, L. R., Donley, P. J., Harrison, E. F., and Hunter, H. L. The control of ifosfamide-induced hematuria with N-acetylcysteine in patients with advanced carcinoma of the lung. Semin.Oncol 1982;9(4 Suppl 1):71-74. View abstract.

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Witschi, A., Junker, E., Schranz, C., Speck, R. F., and Lauterburg, B. H. Supplementation of N-acetylcysteine fails to increase glutathione in lymphocytes and plasma of patients with AIDS. AIDS Res Hum Retroviruses 1995;11(1):141-143. View abstract.

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Kinscherf, R., Fischbach, T., Mihm, S., Roth, S., Hohenhaus-Sievert, E., Weiss, C., Edler, L., Bartsch, P., and Droge, W. Effect of glutathione depletion and oral N-acetyl-cysteine treatment on CD4+ and CD8+ cells. FASEB J. 4-1-1994;8(6):448-451. View abstract.

Chan, T. Y. and Critchley, J. A. Adverse reactions to intravenous N-acetylcysteine in Chinese patients with paracetamol (acetaminophen) poisoning. Hum Exp.Toxicol. 1994;13(8):542-544. View abstract.

Spies, C. D., Reinhart, K., Witt, I., Meier-Hellmann, A., Hannemann, L., Bredle, D. L., and Schaffartzik, W. Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study. Crit Care Med 1994;22(11):1738-1746. View abstract.

Jones, A. L., Bangash, I. H., Bouchier, I. A., and Hayes, P. C. Portal and systemic haemodynamic action of N-acetylcysteine in patients with stable cirrhosis. Gut 1994;35(9):1290-1293. View abstract.

Hansen, N. C., Skriver, A., Brorsen-Riis, L., Balslov, S., Evald, T., Maltbaek, N., Gunnersen, G., Garsdal, P., Sander, P., Pedersen, J. Z., and . Orally administered N-acetylcysteine may improve general well-being in patients with mild chronic bronchitis. Respir.Med 1994;88(7):531-535. View abstract.

Reid, M. B., Stokic, D. S., Koch, S. M., Khawli, F. A., and Leis, A. A. N-acetylcysteine inhibits muscle fatigue in humans. J Clin Invest 1994;94(6):2468-2474. View abstract.

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Bridgeman, M. M., Marsden, M., Selby, C., Morrison, D., and MacNee, W. Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue. Thorax 1994;49(7):670-675. View abstract.

Riise, G. C., Larsson, S., Larsson, P., Jeansson, S., and Andersson, B. A. The intrabronchial microbial flora in chronic bronchitis patients: a target for N-acetylcysteine therapy? Eur.Respir.J 1994;7(1):94-101. View abstract.

Zhang, H., Spapen, H., Nguyen, D. N., Benlabed, M., Buurman, W. A., and Vincent, J. L. Protective effects of N-acetyl-L-cysteine in endotoxemia. Am.J.Physiol 1994;266(5 Pt 2):H1746-H1754. View abstract.

Yim, C. Y., Hibbs, J. B., Jr., McGregor, J. R., Galinsky, R. E., and Samlowski, W. E. Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J Immunol. 6-15-1994;152(12):5796-5805. View abstract.

Beloqui, O., Prieto, J., Suarez, M., Gil, B., Qian, C. H., Garcia, N., and Civeira, M. P. N-acetyl cysteine enhances the response to interferon-alpha in chronic hepatitis C: a pilot study. J.Interferon Res. 1993;13(4):279-282. View abstract.

Suter, P. M., Domenighetti, G., Schaller, M. D., Laverriere, M. C., Ritz, R., and Perret, C. N-acetylcysteine enhances recovery from acute lung injury in man. A randomized, double-blind, placebo-controlled clinical study. Chest 1994;105(1):190-194. View abstract.

Ornaghi, F., Ferrini, S., Prati, M., and Giavini, E. The protective effects of N-acetyl-L-cysteine against methyl mercury embryotoxicity in mice. Fundam.Appl Toxicol. 1993;20(4):437-445. View abstract.

Eylar, E. H., Baez, I., Vazquez, A., and Yamamura, Y. N-acetylcysteine (NAC) enhances interleukin-2 but suppresses interleukin-4 secretion from normal and HIV+ CD4+ T-cells. Cell Mol.Biol (Noisy.-le-grand) 1995;41 Suppl 1:S35-S40. View abstract.

Kottgen, M., Busch, A. E., Hug, M. J., Greger, R., and Kunzelmann, K. N-Acetyl-L-cysteine and its derivatives activate a Cl- conductance in epithelial cells. Pflugers Arch 1996;431(4):549-555. View abstract.

Spies, C., Giese, C., Meier-Hellmann, A., Specht, M., Hannemann, L., Schaffartzik, W., and Reinhart, K. [The effect of prophylactically administered n-acetylcysteine on clinical indicators for tissue oxygenation during hyperoxic ventilation in cardiac risk patients]. Anaesthesist 1996;45(4):343-350. View abstract.

Sochman, J., Vrbska, J., Musilova, B., and Rocek, M. Infarct Size Limitation: acute N-acetylcysteine defense (ISLAND trial): preliminary analysis and report after the first 30 patients. Clin Cardiol. 1996;19(2):94-100. View abstract.

Akerlund, B., Jarstrand, C., Lindeke, B., Sonnerborg, A., Akerblad, A. C., and Rasool, O. Effect of N-acetylcysteine(NAC) treatment on HIV-1 infection: a double-blind placebo-controlled trial. Eur.J Clin Pharmacol 1996;50(6):457-461. View abstract.

Chirkov, Y. Y. and Horowitz, J. D. N-Acetylcysteine potentiates nitroglycerin-induced reversal of platelet aggregation. J Cardiovasc.Pharmacol 1996;28(3):375-380. View abstract.

Hershkovitz, E., Shorer, Z., Levitas, A., and Tal, A. Status epilepticus following intravenous N-acetylcysteine therapy. Isr.J Med Sci 1996;32(11):1102-1104. View abstract.

DiMari, J., Megyesi, J., Udvarhelyi, N., Price, P., Davis, R., and Safirstein, R. N-acetyl cysteine ameliorates ischemic renal failure. Am J Physiol 1997;272(3 Pt 2):F292-F298. View abstract.

Chen, P., Bauer, G., Mitchell, J., Factor, R., Markham, R., and Schwartz, D. H. N-acetyl-cysteine and L-2-oxothiazolidine-4-carboxylic acid enhance contact-dependent growth of HIV in resting peripheral blood mononuclear cells (PBMC) in vitro and increase recovery of HIV from human-PBMC SCID mice. AIDS 1997;11(1):33-41. View abstract.

Bernard, G. R., Wheeler, A. P., Arons, M. M., Morris, P. E., Paz, H. L., Russell, J. A., and Wright, P. E. A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group. Chest 1997;112(1):164-172. View abstract.

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Delneste, Y., Jeannin, P., Potier, L., Romero, P., and Bonnefoy, J. Y. N-acetyl-L-cysteine exhibits antitumoral activity by increasing tumor necrosis factor alpha-dependent T-cell cytotoxicity. Blood 8-1-1997;90(3):1124-1132. View abstract.

Jones, A. L., Jarvie, D. R., Simpson, D., Hayes, P. C., and Prescott, L. F. Pharmacokinetics of N-acetylcysteine are altered in patients with chronic liver disease. Aliment.Pharmacol Ther 1997;11(4):787-791. View abstract.

Walton, N. G., Mann, T. A., and Shaw, K. M. Anaphylactoid reaction to N-acetylcysteine. Lancet 12-15-1979;2(8155):1298. View abstract.

Sheikh-Hamad, D., Timmins, K., and Jalali, Z. Cisplatin-induced renal toxicity: possible reversal by N-acetylcysteine treatment. J Am Soc Nephrol. 1997;8(10):1640-1644. View abstract.

Akerlund, B., Tynell, E., Bratt, G., Bielenstein, M., and Lidman, C. N-acetylcysteine treatment and the risk of toxic reactions to trimethoprim-sulphamethoxazole in primary Pneumocystis carinii prophylaxis in HIV-infected patients. J Infect. 1997;35(2):143-147. View abstract.

Urban, T., Akerlund, B., Jarstrand, C., and Lindeke, B. Neutrophil function and glutathione-peroxidase (GSH-px) activity in healthy individuals after treatment with N-acetyl-L-cysteine. Biomed.Pharmacother. 1997;51(9):388-390. View abstract.

Perry, H. E. and Shannon, M. W. Efficacy of oral versus intravenous N-acetylcysteine in acetaminophen overdose: results of an open-label, clinical trial. J Pediatr 1998;132(1):149-152. View abstract.

Tecklin, J. S. and Holsclaw, D. S., Jr. Bronchial drainage with aerosol medications in cystic fibrosis. Phys.Ther 1976;56(9):999-1003. View abstract.

Salom, M. G., Ramirez, P., Carbonell, L. F., Lopez, Conesa E., Cartagena, J., Quesada, T., Parrilla, P., and Fenoy, F. J. Protective effect of N-acetyl-L-cysteine on the renal failure induced by inferior vena cava occlusion. Transplantation 5-27-1998;65(10):1315-1321. View abstract.

Spapen, H., Zhang, H., Demanet, C., Vleminckx, W., Vincent, J. L., and Huyghens, L. Does N-acetyl-L-cysteine influence cytokine response during early human septic shock? Chest 1998;113(6):1616-1624. View abstract.

Look, M. P., Rockstroh, J. K., Rao, G. S., Barton, S., Lemoch, H., Kaiser, R., Kupfer, B., Sudhop, T., Spengler, U., and Sauerbruch, T. Sodium selenite and N-acetylcysteine in antiretroviral-naive HIV-1-infected patients: a randomized, controlled pilot study. Eur.J Clin Invest 1998;28(5):389-397. View abstract.

Cimino, L., Belisario, M. A., Intrieri, M., D'Ascoli, B., Sacchetti, L., Salvatore, F., and Budillon, G. Effect of N-acetyl-cysteine on lymphomonocyte glutathione and response to interferon treatment in C-virus chronic hepatitis. Ital.J.Gastroenterol.Hepatol. 1998;30(2):189-193. View abstract.

Rattan, A. K. and Arad, Y. Temporal and kinetic determinants of the inhibition of LDL oxidation by N-acetylcysteine (NAC). Atherosclerosis 1998;138(2):319-327. View abstract.

Salahudeen, A., Poovala, V., Parry, W., Pande, R., Kanji, V., Ansari, N., Morrow, J., and Roberts, J. Cisplatin induces N-acetyl cysteine suppressible F2-isoprostane production and injury in renal tubular epithelial cells. J.Am.Soc.Nephrol. 1998;9(8):1448-1455. View abstract.

Binet, H., Simonart, T., Van Vooren, J. P., Heenen, M., Liesnard, C., Delforge, M. L., Farber, C. M., and Parent, D. Porphyria cutanea tarda in a human immunodeficiency virus-infected patient: treatment with N-acetyl-cysteine. Int.J.Dermatol. 1998;37(9):718-719. View abstract.

Walmsley, S. L., Khorasheh, S., Singer, J., and Djurdjev, O. A randomized trial of N-acetylcysteine for prevention of trimethoprim-sulfamethoxazole hypersensitivity reactions in Pneumocystis carinii pneumonia prophylaxis (CTN 057). Canadian HIV Trials Network 057 Study Group. J Acquir.Immune.Defic.Syndr.Hum Retrovirol. 12-15-1998;19(5):498-505. View abstract.

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