Holtmann G, Madisch A, Juergen H, et al. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Ann Mtg Digestive Disease Week 1999 May.

Madisch A, Holtmann G, Mayr G, et al. Treatment of functional dyspepsia with a herbal preparation. A double-blind, randomized, placebo-controlled, multicenter trial. Digestion 2004;69:45-52. View abstract.

Melzer J, Rosch W, Reichling J, et al. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). Aliment Pharmacol Ther 2004;20:1279-87. View abstract.

Storr M, Sibaev A, Weiser D, et al. Herbal extracts modulate the amplitude and frequency of slow waves in circular smooth muscle of mouse small intestine. Digestion 2004;70:257-64. View abstract.

Kemeny-Beke A, Aradi J, Damjanovich J, et al. Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine. Cancer Lett 2006;237:67-75. View abstract.

Colombo ML, Bosisio E. Pharmacological activities of Chelidonium majus L. (Papaveraceae). Pharmacol Res 1996;33:127-34. View abstract.

Ernst E, Schmidt K. Ukrain - a new cancer cure? A systematic review of randomised clinical trials. BMC Cancer 2005;5:69. View abstract.

Stickel F, Poschl G, Seitz HK, et al. Acute hepatitis induced by Greater Celandine (Chelidonium majus). Scand J Gastroenterol 2003;38:565-8. View abstract.

Etxenagusia MA, Anda M, Gonzalez-Mahave I, et al. Contact dermatitis from Chelidonium majus (greater celandine). Contact Dermatitis 2000;43:47. View abstract.

Panzer A, Joubert AM, Bianchi PC, Seegers JC. The antimitotic effects of Ukrain, a Chelidonium majus alkaloid derivative, are reversible in vitro. Cancer Lett 2000;150:85-92. View abstract.

Moro PA, Cassetti F, Giugliano G, et al. Hepatitis from greater celandine (Chelidonium majus L.): Review of literature and report of a new case. J Ethnopharmacol 2009;124:328-32. View abstract.

Khayyal, M. T., El Ghazaly, M. A., Kenawy, S. A., Seif-El-Nasr, M., Mahran, L. G., Kafafi, Y. A., and Okpanyi, S. N. Antiulcerogenic effect of some gastrointestinally acting plant extracts and their combination. Arzneimittelforschung. 2001;51(7):545-553. View abstract.

Stickel, F., Seitz, H. K., Hahn, E. G., and Schuppan, D. [Liver toxicity of drugs of plant origin]. Z.Gastroenterol. 2001;39(3):225-227. View abstract.

Spiridonov, N. A., Konovalov, D. A., and Arkhipov, V. V. Cytotoxicity of some Russian ethnomedicinal plants and plant compounds. Phytother.Res 2005;19(5):428-432. View abstract.

Bondar, G. V., Borota, A. V., Yakovets, Y. I., and Zolotukhin, S. E. Comparative evaluation of the complex treatment of rectal cancer patients (chemotherapy and X-ray therapy, Ukrain monotherapy). Drugs Exp.Clin Res 1998;24(5-6):221-226. View abstract.

Matos, O. C., Baeta, J., Silva, M. J., and Pinto, Ricardo C. Sensitivity of Fusarium strains to Chelidonium majus L. extracts. J Ethnopharmacol. 1999;66(2):151-158. View abstract.

Niederau, C. and Gopfert, E. [The effect of chelidonium- and turmeric root extract on upper abdominal pain due to functional disorders of the biliary system. Results from a placebo-controlled double-blind study]. Med.Klin. 8-15-1999;94(8):425-430. View abstract.

Panzer, A., Joubert, A. M., Eloff, J. N., Albrecht, C. F., Erasmus, E., and Seegers, J. C. Chemical analyses of Ukrain, a semi-synthetic Chelidonium majus alkaloid derivative, fail to confirm its trimeric structure. Cancer Lett. 11-28-2000;160(2):237-241. View abstract.

Zemskov, V. S., Procopchuk, O. L., Susak, Y. M., Zemskov, S. V., Hodysh, Y. Y., and Zemskova, M. V. Ukrain (NSC-631570) in the treatment of pancreas cancer. Drugs Exp.Clin Res 2000;26(5-6):179-190. View abstract.

Uglyanitsa, K. N., Nefyodov, L. I., and Brzosko, V. Comparative evaluation of the efficiency of various Ukrain doses in the combined treatment of breast cancer. Report 1. Clinical aspects of Ukrain application. Drugs Exp.Clin Res 2000;26(5-6):223-230. View abstract.

Fik, E., Wolun-Cholewa, M., Kistowska, M., Warchol, J. B., and Gozdzicka-Jozefiak, A. Effect of lectin from Chelidonium majus L. on normal and cancer cells in culture. Folia Histochem.Cytobiol. 2001;39(2):215-216. View abstract.

Gansauge, F., Ramadani, M., Pressmar, J., Gansauge, S., Muehling, B., Stecker, K., Cammerer, G., Leder, G., and Beger, H. G. NSC-631570 (Ukrain) in the palliative treatment of pancreatic cancer. Results of a phase II trial. Langenbecks Arch.Surg. 2002;386(8):570-574. View abstract.

Zemskov, V., Prokopchuk, O., Susak, Y., Zemskov, S., Tkachenko, O., Hodysh, Y., and Nowicky, W. Efficacy of ukrain in the treatment of pancreatic cancer. Langenbecks Arch.Surg. 2002;387(2):84-89. View abstract.

Baumann, J. C. [Effect of chelidonium, curcuma, absinth and Carduus marianus on the bile and pancreatic secretion in liver diseases]. Med Monatsschr. 1975;29(4):173-180. View abstract.

Juszkiewicz, T., Minta, M., Wlodarczyk, B., and Biernacki, B. Teratological evaluation of Ukrain in hamsters and rats. Drugs Exp.Clin Res 1992;18 Suppl:23-29. View abstract.

Nowicky, J. W., Manolakis, G., Meijer, D., Vatanasapt, V., and Brzosko, W. J. Ukrain both as an anti cancer and immunoregulatory agent. Drugs Exp.Clin Res 1992;18 Suppl:51-54. View abstract.

Staniszewski, A., Slesak, B., Kolodziej, J., Harlozinska-Szmyrka, A., and Nowicky, J. W. Lymphocyte subsets in patients with lung cancer treated with thiophosphoric acid alkaloid derivatives from Chelidonium majus L. (Ukrain). Drugs Exp.Clin Res 1992;18 Suppl:63-67. View abstract.

Lohninger, A. and Hamler, F. Chelidonium majus L. (Ukrain) in the treatment of cancer patients. Drugs Exp.Clin Res 1992;18 Suppl:73-77. View abstract.

Jang, S. I., Kim, B. H., Lee, W. Y., An, S. J., Choi, H. G., Jeon, B. H., Chung, H. T., Rho, J. R., Kim, Y. J., and Chai, K. Y. Stylopine from Chelidonium majus inhibits LPS-induced inflammatory mediators in RAW 264.7 cells. Arch.Pharm.Res 2004;27(9):923-929. View abstract.

Gerencer, M., Turecek, P. L., Kistner, O., Mitterer, A., Savidis-Dacho, H., and Barrett, N. P. In vitro and in vivo anti-retroviral activity of the substance purified from the aqueous extract of Chelidonium majus L. Antiviral Res 2006;72(2):153-156. View abstract.

Nowicky, J. W., Staniszewski, A., Zbroja-Sontag, W., Slesak, B., Nowicky, W., and Hiesmayr, W. Evaluation of thiophosphoric acid alkaloid derivatives from Chelidonium majus L. ("Ukrain") as an immunostimulant in patients with various carcinomas. Drugs Exp.Clin Res 1991;17(2):139-143. View abstract.

Gansauge, F., Ramadani, M., Schwarz, M., Beger, H. G., Lotspeich, E., and Poch, B. The clinical efficacy of adjuvant systemic chemotherapy with gemcitabine and NSC-631570 in advanced pancreatic cancer. Hepatogastroenterology 2007;54(75):917-920. View abstract.

Ardjah, H. [Therapeutic aspects of functional symptoms of the upper abdomen in biliary tract diseases]. Fortschr.Med.Suppl 1991;115:2-8. View abstract.

Hardeman, E., Van, Overbeke L., Ilegems, S., and Ferrante, M. Acute hepatitis induced by greater celandine (Chelidonium majus). Acta Gastroenterol.Belg. 2008;71(2):281-282. View abstract.

Gilca, M., Gaman, L., Panait, E., Stoian, I., and Atanasiu, V. Chelidonium majus--an integrative review: traditional knowledge versus modern findings. Forsch.Komplementmed. 2010;17(5):241-248. View abstract.

Teschke, R., Glass, X., and Schulze, J. Herbal hepatotoxicity by Greater Celandine (Chelidonium majus): causality assessment of 22 spontaneous reports. Regul.Toxicol.Pharmacol. 2011;61(3):282-291. View abstract.

Teschke, R., Glass, X., Schulze, J., and Eickhoff, A. Suspected Greater Celandine hepatotoxicity: liver-specific causality evaluation of published case reports from Europe. Eur.J Gastroenterol.Hepatol. 2012;24(3):270-280. View abstract.

Pinto, Garcia, V, Vicente, P. R., Barez, A., Soto, I., Candas, M. A., and Coma, A. [Hemolytic anemia induced by Chelidonium majus. Clinical case]. Sangre (Barc.) 1990;35(5):401-403. View abstract.

Teschke, R., Frenzel, C., Glass, X., Schulze, J., and Eickhoff, A. Greater Celandine hepatotoxicity: a clinical review. Ann.Hepatol. 2012;11(6):838-848. View abstract.

Xian, M. S., Hayashi, K., Lu, J. P., and Awai, M. Efficacy of traditional Chinese herbs on squamous cell carcinoma of the esophagus: histopathologic analysis of 240 cases. Acta Med.Okayama 1989;43(6):345-351. View abstract.

Baumann, J. C., Heintze, K., and Muth, H. W. [Clinico-experimental studies on the secretion of bile, pancreatic and gastric juice under the influence of phytocholagogous agents of a suspension of Carduus marianus, Chelidonium and Curcuma]. Arzneimittelforschung. 1971;21(1):98-101. View abstract.

Kim, H. K., Farnsworth, N. R., Blomster, R. N., and Fong, H. H. Biological and phytochemical evaluation of plants. V. Isolation of two cytotoxic alkaloids from Chelidonium majus. J Pharm.Sci. 1969;58(3):372-374. View abstract.

Taborska, E., Bochorakova, H., Dostal, J., and Paulova, H. [The greater celandine (Chelidonium majus L.)--review of present knowledge]. Ceska.Slov.Farm. 1995;44(2):71-75. View abstract.

Boegge, S. C., Kesper, S., Verspohl, E. J., and Nahrstedt, A. Reduction of ACh-induced contraction of rat isolated ileum by coptisine, (+)-caffeoylmalic acid, Chelidonium majus, and Corydalis lutea extracts. Planta Med. 1996;62(2):173-174. View abstract.

Susak, Y. M., Zemskov, V. S., Yaremchuk, O. Y., Kravchenco, O. B., Yatsyk, I. M., and Korsh, O. B. Comparison of chemotherapy and X-ray therapy with Ukrain monotherapy for colorectal cancer. Drugs Exp.Clin Res 1996;22(3-5):115-122. View abstract.

Steinacker, J., Kroiss, T., Korsh, O. B., and Melnyk, A. Ukrain therapy in a frontal anaplastic grade III astrocytoma (case report). Drugs Exp.Clin Res 1996;22(3-5):275-277. View abstract.

Voltchek, I. V., Liepins, A., Nowicky, J. W., and Brzosko, W. J. Potential therapeutic efficacy of Ukrain (NSC 631570) in AIDS patients with Kaposi's sarcoma. Drugs Exp.Clin Res 1996;22(3-5):283-286. View abstract.

Vavreckova, C., Gawlik, I., and Muller, K. Benzophenanthridine alkaloids of Chelidonium majus; II. Potent inhibitory action against the growth of human keratinocytes. Planta Med. 1996;62(6):491-494. View abstract.

Vavreckova, C., Gawlik, I., and Muller, K. Benzophenanthridine alkaloids of Chelidonium majus; I. Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism. Planta Med. 1996;62(5):397-401. View abstract.

Khmel'nitskaia, N. M., Vorob'ev, K. V., Kliachko, L. L., Ankhimova, E. S., Kosenko, V. A., Tyrnova, E. V., Mal'tseva, G. S., and Medvedev, E. A. [A comparative study of conservative treatment schemes in chronic tonsillitis in children]. Vestn.Otorinolaringol. 1998;(4):39-42. View abstract.

Hiller, K. O., Ghorbani, M., and Schilcher, H. Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum. Planta Med. 1998;64(8):758-760. View abstract.

Susak, Y. M., Yaremchuk, O. Y., Zemskov, S., Kravchenco, O. B., Liepins, A., and Yatsyk, I. M. Randomised clinical study of Ukrain on colorectal cancer. Eur J Cancer 1995;31(S153)

von Zerssen, D. Die Beschwerden-Liste. Manual. Weinheim: Beltz Test;1976.

Kniebel, R. and Urlacher, W. Therapie krampfartiger Abdominalschmerzen. Hochdosierter Schollkrautextrakt. Z Allg Med 1993;69:680-684.

Holtmann, G., Madisch, A., and Juergen, H. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Ann Mtg Digestive Disease Week 1999;

Niederau, C. and Gopfert, C. Effect of extracts of C&T on upper abdominal pain due to functional disorders of biliary system. Medica Klinic 1999;94(8):425-430.

Pantano F, Mannocchi G, Marinelli E, Gentili S, Graziano S, Busardò FP, di Luca NM. Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature. Eur Rev Med Pharmacol Sci. 2017 Mar;21(1 Suppl):46-52. View abstract.

Baek SC, Ryu HW, Kang MG, et al. Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid. Bioorg Med Chem Lett. 2018;28(14):2403-2407. View abstract.

Liu Y, Cui T, Peng Y, Ji M, Zheng J. Mechanism-based inactivation of cytochrome P450 2D6 by chelidonine. J Biochem Mol Toxicol. 2019;33(2):e22251. View abstract.