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902
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903
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914
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915
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916
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918
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1403
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2203
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10286
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30000
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30001
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30002
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30003
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30004
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30006
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30007
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30008
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30009
Curcio, J. J., Kim, L. S., Wollner, D., and Pockaj, B. A. The potential of 5-hydryoxytryptophan for hot flash reduction: a hypothesis. Altern Med Rev 2005;10(3):216-221. View abstract.
30011
Halladay, A. K., Wagner, G. C., Sekowski, A., Rothman, R. B., Baumann, M. H., and Fisher, H. Alterations in alcohol consumption, withdrawal seizures, and monoamine transmission in rats treated with phentermine and 5-hydroxy-L-tryptophan. Synapse 2006;59(5):277-289. View abstract.
30013
Lesch, K. P., Hoh, A., Disselkamp-Tietze, J., Wiesmann, M., Osterheider, M., and Schulte, H. M. 5-Hydroxytryptamine1A receptor responsivity in obsessive-compulsive disorder. Comparison of patients and controls. Arch Gen Psychiatry 1991;48(6):540-547. View abstract.
30015
Petre-Quadens, O. and De Lee, C. 5-Hydroxytryptophan and sleep in Down's syndrome. J Neurol Sci 1975;26(3):443-453. View abstract.
30016
Halford, J. C., Harrold, J. A., Boyland, E. J., Lawton, C. L., and Blundell, J. E. Serotonergic drugs : effects on appetite expression and use for the treatment of obesity. Drugs 2007;67(1):27-55. View abstract.
30018
Cangiano C, Ceci F, Cairella M, et al. Effects of 5-hydroxytryptophan on eating behavior and adherence to dietary prescriptions in obese adult subjects. Adv Exp Med Biol 1991;294:591-3. View abstract.
30020
Meolie, A. L., Rosen, C., Kristo, D., Kohrman, M., Gooneratne, N., Aguillard, R. N., Fayle, R., Troell, R., Townsend, D., Claman, D., Hoban, T., and Mahowald, M. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. J Clin.Sleep Med 4-15-2005;1(2):173-187. View abstract.
30022
Morrow, J. D., Vikraman, S., Imeri, L., and Opp, M. R. Effects of serotonergic activation by 5-hydroxytryptophan on sleep and body temperature of C57BL/6J and interleukin-6-deficient mice are dose and time related. Sleep 1-1-2008;31(1):21-33. View abstract.
30023
Horvath, G. A., Stockler-Ipsiroglu, S. G., Salvarinova-Zivkovic, R., Lillquist, Y. P., Connolly, M., Hyland, K., Blau, N., Rupar, T., and Waters, P. J. Autosomal recessive GTP cyclohydrolase I deficiency without hyperphenylalaninemia: evidence of a phenotypic continuum between dominant and recessive forms. Mol.Genet.Metab 2008;94(1):127-131. View abstract.
30026
Liu, K. M., Liu, T. T., Lee, N. C., Cheng, L. Y., Hsiao, K. J., and Niu, D. M. Long-term follow-up of Taiwanese Chinese patients treated early for 6-pyruvoyl-tetrahydropterin synthase deficiency. Arch Neurol. 2008;65(3):387-392. View abstract.
30029
Jacobsen, J. P., Nielsen, E. O., Hummel, R., Redrobe, J. P., Mirza, N., and Weikop, P. Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan. Psychopharmacology (Berl) 2008;199(2):137-150. View abstract.
30035
Schaefer, M., Winterer, J., Sarkar, R., Uebelhack, R., Franke, L., Heinz, A., and Friebe, A. Three cases of successful tryptophan add-on or monotherapy of hepatitis C and IFNalpha-associated mood disorders. Psychosomatics 2008;49(5):442-446. View abstract.
30036
Pons, R. The phenotypic spectrum of paediatric neurotransmitter diseases and infantile parkinsonism. J Inherit.Metab Dis 2009;32(3):321-332. View abstract.
30038
Longo, N. Disorders of biopterin metabolism. J Inherit.Metab Dis 2009;32(3):333-342. View abstract.
30040
Hendricks, E. J., Rothman, R. B., and Greenway, F. L. How physician obesity specialists use drugs to treat obesity. Obesity.(Silver.Spring) 2009;17(9):1730-1735. View abstract.
30041
Chae, H. S., Kang, O. H., Choi, J. G., Oh, Y. C., Lee, Y. S., Jang, H. J., Kim, J. H., Park, H., Jung, K. Y., Sohn, D. H., and Kwon, D. Y. 5-hydroxytryptophan acts on the mitogen-activated protein kinase extracellular-signal regulated protein kinase pathway to modulate cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 cells. Biol Pharm Bull 2009;32(4):553-557. View abstract.
30044
Rothman, R. B. Treatment of obesity with "combination" pharmacotherapy. Am J Ther 2010;17(6):596-603. View abstract.
30046
Trujillo-Martin, M. M., Serrano-Aguilar, P., Monton-Alvarez, F., and Carrillo-Fumero, R. Effectiveness and safety of treatments for degenerative ataxias: a systematic review. Mov Disord. 6-15-2009;24(8):1111-1124. View abstract.
30047
Shell W, Bullias D, Charuvastra E, et al. A randomized, placebo-controlled trial of an amino acid preparation on timing and quality of sleep. Am J Ther 2010;17:133-9. View abstract.
30048
Maissen CP, Ludin HP. [Comparison of the effect of 5-hydroxytryptophan and propranolol in the interval treatment of migraine]. Schweiz Med Wochenschr 1991;121:1585-90. View abstract.
30051
Rondanelli M, Klersy C, Iadarola P, et al. Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation. Int J Obes (Lond) 2009;33:1174-1182. View abstract.
30055
Weeks, B. S. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Med Sci Monit. 2009;15(11):RA256-RA262. View abstract.
30061
Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas 2010;65:383-5. View abstract.
30067
Leu-Semenescu, S., Arnulf, I., Decaix, C., Moussa, F., Clot, F., Boniol, C., Touitou, Y., Levy, R., Vidailhet, M., and Roze, E. Sleep and rhythm consequences of a genetically induced loss of serotonin. Sleep 3-1-2010;33(3):307-314. View abstract.
30076
Iovieno, N., Dalton, E. D., Fava, M., and Mischoulon, D. Second-tier natural antidepressants: review and critique. J Affect.Disord. 2011;130(3):343-357. View abstract.
30082
Gendle, M. H. and Golding, A. C. Oral administration of 5-hydroxytryptophan (5-HTP) impairs decision making under ambiguity but not under risk: evidence from the Iowa Gambling Task. Hum Psychopharmacol. 2010;25(6):491-499. View abstract.
30088
Cross, D. R., Kellermann, G., McKenzie, L. B., Purvis, K. B., Hill, G. J., and Huisman, H. A randomized targeted amino acid therapy with behaviourally at-risk adopted children. Child Care Health Dev. 2011;37(5):671-678. View abstract.
30091
Adamsen, D., Meili, D., Blau, N., Thony, B., and Ramaekers, V. Autism associated with low 5-hydroxyindolacetic acid in CSF and the heterozygous SLC6A4 gene Gly56Ala plus 5-HTTLPR L/L promoter variants. Mol.Genet.Metab 2011;102(3):368-373. View abstract.
30093
den Boer JA, Westenberg HG. Behavioral, neuroendocrine, and biochemical effects of 5-hydroxytryptophan administration in panic disorder. Psychiatry Res 1990;31:267-78. View abstract.
30094
Bainbridge, M. N., Wiszniewski, W., Murdock, D. R., Friedman, J., Gonzaga-Jauregui, C., Newsham, I., Reid, J. G., Fink, J. K., Morgan, M. B., Gingras, M. C., Muzny, D. M., Hoang, L. D., Yousaf, S., Lupski, J. R., and Gibbs, R. A. Whole-genome sequencing for optimized patient management. Sci Transl.Med 6-15-2011;3(87):87re3. View abstract.
30095
Morrison, K. E. Whole-genome sequencing informs treatment: personalized medicine takes another step forward. Clin Chem 2011;57(12):1638-1640. View abstract.
30096
Horvath, G. A., Selby, K., Poskitt, K., Hyland, K., Waters, P. J., Coulter-Mackie, M., and Stockler-Ipsiroglu, S. G. Hemiplegic migraine, seizures, progressive spastic paraparesis, mood disorder, and coma in siblings with low systemic serotonin. Cephalalgia 2011;31(15):1580-1586. View abstract.
30097
Dill, P., Wagner, M., Somerville, A., Thony, B., Blau, N., and Weber, P. Child neurology: paroxysmal stiffening, upward gaze, and hypotonia: hallmarks of sepiapterin reductase deficiency. Neurology 1-31-2012;78(5):e29-e32. View abstract.
30098
Sarris, J. Clinical depression: an evidence-based integrative complementary medicine treatment model. Altern.Ther.Health Med. 2011;17(4):26-37. View abstract.
30100
Jukic T, Rojc B, Boben-Bardutzky D, Hafner M, Ihan A. The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. Coll Antropol 2011;35:1225-30. View abstract.
30101
Friedman, J., Roze, E., Abdenur, J. E., Chang, R., Gasperini, S., Saletti, V., Wali, G. M., Eiroa, H., Neville, B., Felice, A., Parascandalo, R., Zafeiriou, D. I., Arrabal-Fernandez, L., Dill, P., Eichler, F. S., Echenne, B., Gutierrez-Solana, L. G., Hoffmann, G. F., Hyland, K., Kusmierska, K., Tijssen, M. A., Lutz, T., Mazzuca, M., Penzien, J., Poll-The BT, Sykut-Cegielska, J., Szymanska, K., Thony, B., and Blau, N. Sepiapterin reductase deficiency: a treatable mimic of cerebral palsy. Ann Neurol. 2012;71(4):520-530. View abstract.
30103
Pan, L., McKain, B. W., Madan-Khetarpal, S., Mcguire, M., Diler, R. S., Perel, J. M., Vockley, J., and Brent, D. A. GTP-cyclohydrolase deficiency responsive to sapropterin and 5-HTP supplementation: relief of treatment-refractory depression and suicidal behaviour. BMJ Case.Rep. 2011;2011 View abstract.
30104
Baraldi, S., Hepgul, N., Mondelli, V., and Pariante, C. M. Symptomatic treatment of interferon-alpha-induced depression in hepatitis C: a systematic review. J Clin Psychopharmacol. 2012;32(4):531-543. View abstract.
30105
Opladen, T., Hoffmann, G. F., and Blau, N. An international survey of patients with tetrahydrobiopterin deficiencies presenting with hyperphenylalaninaemia. J Inherit.Metab Dis 2012;35(6):963-973. View abstract.
30108
Hallin, M. L., Mahmoud, K., Viswanath, A., and Gama, R. 'Sweet Dreams', 'Happy Days' and elevated 24-h urine 5-hydroxyindoleacetic acid excretion. Ann Clin Biochem. 2013;50(Pt 1):80-82. View abstract.
30111
Zarcone, V. P., Jr. and Hoddes, E. Effects of 5-hydroxytryptophan on fragmentation of REM sleep in alcoholics. Am J Psychiatry 1975;132(1):74-76. View abstract.
30112
Jangid P, Malik P, Singh P, Sharma M, Gulia AK. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr 2013;6:29-34. View abstract.
30114
Ceci F, Cangiano C, Cairella M, et al. The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. J Neural Transm 1989;76:109-17. View abstract.
30117
Anders, T. F., Cann, H. M., Ciaranello, R. D., Barchas, J. D., and Berger, P. A. Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. Neuropadiatrie. 1978;9(2):157-166. View abstract.
30118
Rousseau JJ. Effects of a levo-5-hydroxytryptophan-dihydroergocristine combination on depression and neuropsychic performance: a double-blind placebo-controlled clinical trial in elderly patients. Clin Ther 1987;9:267-72. View abstract.
30119
Magnussen, I. and Nielsen-Kudsk, F. Pharmacokinetics of intravenously administered L-5-hydroxytryptophan in man. Acta Pharmacol.Toxicol.(Copenh) 1979;44(4):308-314. View abstract.
30120
Kaneko M, Kumashiro H, Takahashi Y, Hoshino Y. L-5HTP treatment and serum 5-HT level after L-5-HTP loading on depressed patients. Neuropsychobiology 1979;5:232-40. View abstract.
30121
Nolen, W. A., van de Putte, J. J., Dijken, W. A., Kamp, J. S., Blansjaar, B. A., Kramer, H. J., and Haffmans, J. Treatment strategy in depression. II. MAO inhibitors in depression resistant to cyclic antidepressants: two controlled crossover studies with tranylcypromine versus L-5-hydroxytryptophan and nomifensine. Acta Psychiatr.Scand 1988;78(6):676-683. View abstract.
30122
Zmilacher, K., Battegay, R., and Gastpar, M. L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression. Neuropsychobiology 1988;20(1):28-35. View abstract.
30123
De Giorgis G, Miletto R, Iannuccelli M, Camuffo M, Scerni S. Headache in association with sleep disorders in children: a psychodiagnostic evaluation and controlled clinical study--L-5-HTP versus placebo. Drugs Exp Clin Res 1987;13:425-33. View abstract.
30124
Kahn RS, Westenberg HG, Verhoeven WM, et al. Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. Int Clin Psychopharmacol 1987;21:33-45. View abstract.
30125
Angst J, Woggon B, Schoepf J. The treatment of depression with L-5-hydroxytryptophan versus imipramine. Results of two open and one double-blind study. Arch Psychiatr Nervenkr 1977;224:175-86. View abstract.
30126
Sueldo, C. E., Duda, M., and Kletzky, O. A. Influence of sequential doses of 5-hydroxytryptophan on prolactin release. Am J Obstet.Gynecol. 1986;154(2):424-427. View abstract.
30127
Irwin, M. R., Marder, S. R., Fuentenebro, F., and Yuwiler, A. L-5-hydroxytryptophan attenuates positive psychotic symptoms induced by D-amphetamine. Psychiatry Res. 1987;22(4):283-289. View abstract.
30128
Santucci M, Cortelli P, Rossi PG, Baruzzi A, Sacquegna T. L-5-hydroxytryptophan versus placebo in childhood migraine prophylaxis: a double-blind crossover study. Cephalalgia 1986;6:155-7. View abstract.
30129
Titus F, Dávalos A, Alom J, Codina A. 5-Hydroxytryptophan versus methysergide in the prophylaxis of migraine. Randomized clinical trial. Eur Neurol 1986;25:327-9. View abstract.
30130
De Benedittis G, Massei R. Serotonin precursors in chronic primary headache. A double-blind cross-over study with L-5-hydroxytryptophan vs. placebo. J Neurosurg Sci 1985;29:239-48. View abstract.
30131
Nolen WA, van de Putte JJ, Dijken WA, Kamp JS. L-5HTP in depression resistant to re-uptake inhibitors. An open comparative study with tranylcypromine. Br J Psychiatry 1985;147:16-22. View abstract.
30132
Van Woert, M. H., Rosenbaum, D., Howieson, J., and Bowers, M. B., Jr. Long-term therapy of myoclonus and other neurologic disorders with L-5- hydroxytryptophan and carbidopa. N Engl J Med 1-13-1977;296(2):70-75. View abstract.
30133
Chadwick, D., Hallett, M., Harris, R., Jenner, P., Reynolds, E. H., and Marsden, C. D. Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam. Brain 1977;100(3):455-487. View abstract.
30137
Zarcone, V., Kales, A., Scharf, M., Tan, T. L., Simmons, J. Q., and Dement, W. C. Repeated oral ingestion of 5-hydroxytryptophan. The effect on behavior and sleep processes in two schizophrenic children. Arch Gen Psychiatry 1973;28(6):843-846. View abstract.
30138
van Praag HM, Korf J, Dols LC, Schut T. A pilot study of the predictive value of the probenecid test in application of 5-hydroxytryptophan as antidepressant. Psychopharmacologia 1972;25:14-21. View abstract.
30139
Wyatt, R. J., Vaughan, T., Galanter, M., Kaplan, J., and Green, R. Behavioral changes of chronic schizophrenic patients given L-5- hydroxytryptophan. Science 9-22-1972;177(54):1124-1126. View abstract.
30140
Chase, T. N., Ng, L. K., and Watanabe, A. M. Parkinson's disease. Modification by 5-hydroxytryptophan. Neurology 1972;22(5):479-484. View abstract.
30141
Soulairac, A. [Hypnotic action of mecloqualone. Comparison with placebo effects and secobarbital]. Presse Med 4-10-1971;79(18):817-818. View abstract.
30143
van Praag, H. and de Hann, S. Depression vulnerability and 5-hydroxytryptophan prophylaxis. Psychiatry Res. 1980;3(1):75-83. View abstract.
30144
van Praag, H. M. and de Haan, S. Chemoprophylaxis of depressions. An attempt to compare lithium with 5- hydroxytryptophan. Acta Psychiatr.Scand Suppl 1981;290:191-201. View abstract.
30145
Magnussen, I., Jensen, T. S., Rand, J. H., and Van Woert, M. H. Plasma accumulation of metabolism of orally administered single dose L- 5-hydroxytryptophan in man. Acta Pharmacol.Toxicol.(Copenh) 1981;49(3):184-189. View abstract.
30146
Magnussen, I. and Van Woert, M. H. Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors. Eur.J Clin Pharmacol 1982;23(1):81-86. View abstract.
30147
Trouillas P. Regression of cerebellar syndrome with long-term administration of 5-HTP or the combination of 5-HTP-benserazide: 21 cases with quantified symptoms processed by computer. Ital J Neurol Sci 1984;5(3):253-266. View abstract.
30148
van Praag, H. M. In search of the mode of action of antidepressants: 5-HTP/tyrosine mixtures in depression. Adv Biochem Psychopharmacol. 1984;39:301-314. View abstract.
30149
Quadbeck, H., Lehmann, E., and Tegeler, J. Comparison of the antidepressant action of tryptophan, tryptophan/5- hydroxytryptophan combination and nomifensine. Neuropsychobiology 1984;11(2):111-115. View abstract.
30150
Bono, G., Micieli, G., Sances, G., Calvani, M., and Nappi, G. L-5HTP treatment in primary headaches: an attempt at clinical identification of responsive patients. Cephalalgia 1984;4(3):159-165. View abstract.
30151
Longo G, Rudoi I, Iannuccelli M, Strinati R, Panizon F. [Treatment of essential headache in developmental age with L-5-HTP (cross over double-blind study versus placebo)]. Pediatr Med Chir 1984;6:241-5. View abstract.
30153
Pueschel SM, Reed RB, Cronk CE, Goldstein BI. 5-hydroxytryptophan and pyridoxine. Their effects in young children with Down's syndrome. Am J Dis Child 1980;134:838-44. View abstract.
30156
Trouillas, P., Garde, A., Robert, J. M., and Adeleine, P. [Regression of human cerebellar ataxia under long term administration of 5-hydroxytryptophan]. C.R.Seances Acad Sci III 1-5-1981;292(1):119-122. View abstract.
30157
Magnussen, I. and Nielsen-Kudsk, F. Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state. Acta Pharmacol Toxicol.(Copenh) 1980;46(4):257-262. View abstract.
30158
van Hiele LJ. l-5-Hydroxytryptophan in depression: the first substitution therapy in psychiatry? The treatment of 99 out-patients with 'therapy-resistant' depressions. Neuropsychobiology 1980;6:230-40. View abstract.
30159
Thal, L. J., Sharpless, N. S., Wolfson, L., and Katzman, R. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol 1980;7(6):570-576. View abstract.
30160
Trouillas, P., Garde, A., Robert, J. M., Renaud, B., Adeleine, P., Bard, J., and Brudon, F. [Regression of the cerebellar syndrome under long-term administration of 5-HTP or the combination of 5-HTP and benserazide. 26 cases quantified and treated using computer methods]. Rev Neurol.(Paris) 1982;138(5):415-435. View abstract.
30161
Thomson, J., Rankin, H., Ashcroft, G. W., Yates, C. M., McQueen, J. K., and Cummings, S. W. The treatment of depression in general practice: a comparison of L- tryptophan, amitriptyline, and a combination of L-tryptophan and amitriptyline with placebo. Psychol Med 1982;12(4):741-751. View abstract.
30162
Pranzatelli, M. R., Tate, E., Huang, Y., Haas, R. H., Bodensteiner, J., Ashwal, S., and Franz, D. Neuropharmacology of progressive myoclonus epilepsy: response to 5- hydroxy-L-tryptophan. Epilepsia 1995;36(8):783-791. View abstract.
30163
Alino, J. J., Gutierrez, J. L., and Iglesias, M. L. 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study. Int Pharmacopsychiatry 1976;11(1):8-15. View abstract.
30164
Wessel K, Hermsdörfer J, Deger K, et al. Double-blind crossover study with levorotatory form of hydroxytryptophan in patients with degenerative cerebellar diseases. Arch Neurol 1995;52:451-5. View abstract.
30165
Trouillas P, Serratrice G, Laplane D, et al. Levorotatory form of 5-hydroxytryptophan in Friedreich's ataxia. Results of a double-blind drug-placebo cooperative study. Arch Neurol 1995;52:456-60. View abstract.
30167
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