Two capsules contain: Picrorhiza plant standardized extract (picrorrhiza kurroa, 20 mg kutkin) 500 mg. Other Ingredients: Capsule (plant-derived cellulose), Maltodextrin, Magnesium Stearate, Silica.
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Below is general information about the effectiveness of the known ingredients contained in the product Picrorrhiza. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Picrorrhiza. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used orally and appropriately. Picrorhiza seems to be safe when used for up to 1 year (11493,11848,11858).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Picrorrhiza. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Evidence from animal research suggests that an extract of picrorhiza can reduce fasting and non-fasting blood sugar levels (57220). Theoretically, picrorhiza might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
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Picrorhiza seems to have immunostimulating activity (11492,11853). Theoretically, picrorhiza may interfere with immunosuppressant therapy. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).
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Below is general information about the adverse effects of the known ingredients contained in the product Picrorrhiza. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, picrorhiza may cause vomiting, rash, anorexia, diarrhea, itching, and giddiness (11858).
Dermatologic ...Orally, picrorhiza may cause rash and itching (11858).
Gastrointestinal ...Orally, picrorhiza may cause vomiting, anorexia, and diarrhea (11858).
Neurologic/CNS ...Orally, picrorhiza may cause giddiness (11858).