Each 1 ml serving contains: Marrubium vulgare 1:4 extract (DHE: 250 mg) 1 ml. Other Ingredients: Grain Alcohol, Purified Water.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
Below is general information about the effectiveness of the known ingredients contained in the product Horehound Tincture. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Horehound Tincture. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods. White horehound has Generally Recognized as Safe (GRAS) status in the US (4912).
POSSIBLY SAFE ...when used orally and appropriately (2,12).
POSSIBLY UNSAFE ...when used orally in excessive amounts; white horehound may have a purgative effects (4,12). There is insufficient reliable information available about the safety of the topical use of white horehound.
PREGNANCY: LIKELY UNSAFE
when used orally; white horehound might have abortifacient effect (19), or stimulate menstrual flow and the uterus (12).
There is insufficient reliable information available about the safety of topical use during pregnancy; avoid using.
LACTATION:
There is insufficient reliable information available about the safety of oral use during lactation; avoid amounts greater than those commonly found in foods.
There is insufficient reliable information available about the safety of topical use during lactation; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Horehound Tincture. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Evidence from animal research suggests that white horehound might lower blood glucose (23603,26149). However, preliminary clinical research suggests that white horehound only slightly lowers blood glucose when taken in combination with antidiabetic agents, suggesting that the effect may not be clinically significant (86369). Until more is known, use with caution. Theoretically, white horehound may have additive effects when used by patients taking antidiabetic drugs. The dose of diabetes medications might need to be adjusted. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
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Evidence from animal research suggests that taking white horehound extract lowers blood pressure (49408,86367). Theoretically, taking white horehound with antihypertensive drugs might enhance therapeutic effects and increase the risk of hypotension. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
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Below is general information about the adverse effects of the known ingredients contained in the product Horehound Tincture. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, white horehound may cause nausea, dry mouth, excessive salivation, loss of appetite, and dizziness in some patients (86369).
Large amounts of white horehound (exact dose is unclear) may cause purgative effects (4,12).
Topically, skin contact with the plant juice may cause contact dermatitis (4).
Dermatologic ...Topically, skin contact with the plant juice may cause contact dermatitis (4).
Gastrointestinal ...Orally, clinical research shows that drinking one cup of tea prepared with white horehound 1 gram three times daily for 3 weeks may cause nausea, dry mouth, excessive salivation, and loss of appetite in some patients (86369). Intake of large amounts of white horehound (exact dose is unclear) may cause purgative effects (4,12).
Neurologic/CNS ...Orally, clinical research shows that drinking one cup of tea prepared with white horehound 1 gram three times daily for 3 weeks may cause dizziness in some patients (86369).
