Each capsule contains: Barosma betulina 4:1 extract (DHE: 406 mg) 100 mg • Orthosiphon stamineus 4:1 extract (DHE: 600 mg) 150 mg • Solidago virgaurea l. (DHE: 600 mg) 150 mg. Other Ingredients: Gelatin, Magnesium Stearate.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
Below is general information about the effectiveness of the known ingredients contained in the product Star I Nol. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of buchu.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Star I Nol. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when the leaf is used in amounts commonly found in foods. Buchu has Generally Recognized As Safe status (GRAS) for use in foods in the US (4912).
POSSIBLY SAFE ...when the leaf is used orally and appropriately in medicinal amounts (2,12).
POSSIBLY UNSAFE ...when excessive amounts of buchu leaf are taken orally or when the oil is ingested. Buchu contains pulegone, a known hepatotoxin (4). Pulegone is a major component of the oil. It is more abundant in buchu products that come from Agathosma crenulata (93681).
PREGNANCY: LIKELY UNSAFE
when used in medicinal amounts; buchu is reported to be an abortifacient (4).
LACTATION: POSSIBLY SAFE
when used in food amounts.
There is insufficient reliable information available about the safety of using larger amounts; avoid using.
POSSIBLY SAFE ...when used topically as a toothpaste, short-term. A specific toothpaste (Bucovia, Givaudan) containing goldenrod extract 0.3% and sodium fluoride 0.15% has been used safely twice daily for up to 4 weeks (105115). There is insufficient reliable information available about the safety of goldenrod when used orally or when applied topically to the skin.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
POSSIBLY SAFE ...when used orally and appropriately, short-term. Java tea 100 mg daily has been safely used in a clinical trial for 8 weeks (94851).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Star I Nol. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Buchu may have antiplatelet effects (6002). Theoretically, buchu may enhance the effects of anticoagulant or antiplatelet drugs and increase the risk of bleeding in some patients. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
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Buchu contains pulegone, a known hepatotoxin (4,93681). There is some concern that buchu may adversely affect the liver, especially when the leaf is used in large doses or the oil is ingested (93681). Theoretically, concomitant use with hepatotoxic drugs might increase the risk of liver damage. Some of these drugs include acarbose (Precose, Prandase), amiodarone (Cordarone), atorvastatin (Lipitor), azathioprine (Imuran), carbamazepine (Tegretol), cerivastatin (Baycol), diclofenac (Voltaren), felbamate (Felbatol), fenofibrate (Tricor), fluvastatin (Lescol), gemfibrozil (Lopid), isoniazid, itraconazole, (Sporanox), ketoconazole (Nizoral), leflunomide (Arava), lovastatin (Mevacor), methotrexate (Rheumatrex), nevirapine (Viramune), niacin, nitrofurantoin (Macrodantin), pioglitazone (Actos), pravastatin (Pravachol), pyrazinamide, rifampin (Rifadin), ritonavir (Norvir), rosiglitazone (Avandia), simvastatin (Zocor), tacrine (Cognex), tamoxifen, terbinafine (Lamisil), valproic acid, and zileuton (Zyflo)
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Buchu is thought to have diuretic properties (93681). Theoretically, buchu might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
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Theoretically, goldenrod might increase the effects and adverse effects of diuretic drugs.
 Details
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Some preliminary clinical evidence suggests that Java tea has antihypertensive effects. Further, animal research suggests that Java tea has diuretic properties (94851). Theoretically, taking Java tea with other antihypertensive drugs might increase the effects and risk for hypotension with these drugs.
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Animal research suggests that Java tea has diuretic properties (94851). Theoretically, due to these effects, Java tea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
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Below is general information about the adverse effects of the known ingredients contained in the product Star I Nol. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, buchu leaf can cause GI and kidney irritation (4,6) and increase menstrual flow (6). Buchu is also a reported abortifacient (4).
Gastrointestinal ...Orally, buchu may cause gastrointestinal irritation (4,6).
Genitourinary ...Orally, buchu may increase menstrual flow (6). Buchu is also a reported abortifacient (4).
General
...There is a limited amount of information available about the adverse effects of goldenrod.
Most Common Adverse Effects:
Topically: Allergic contact dermatitis in sensitive individuals.
Dermatologic ...Topically, goldenrod has been reported to cause allergic contact dermatitis (52558,52581).
Immunologic ...Topically, goldenrod has been reported to cause allergic contact dermatitis (52558,52581). Environmental exposure to goldenrod has been reported to cause an allergic reaction involving rhinoconjunctivitis and bronchial asthma in one case report (52558).
Pulmonary/Respiratory ...Environmental exposure to goldenrod has been reported to cause a delayed allergic reaction involving rhinoconjunctivitis and bronchial asthma in one case report of a 42 year-old woman who worked at a flower shop and was exposed to members of the Asteraceae/Compositae family, including goldenrod (52558).
General ...Orally, Java tea seems to be well tolerated. However, a thorough evaluation of safety outcomes has not been conducted.
