Each tablet contains: Armoracia rusticana p. gaertn. er al. (brassicacear) 500 mg. Other Ingredients: Calcium Phosphate Dibasic Dihydrate, Cellulose, Magnesium Stearate, Silicon Dioxide.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
Below is general information about the effectiveness of the known ingredients contained in the product Horseradish 500 mg Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Horseradish 500 mg Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when the root is used orally in amounts commonly found in foods. Horseradish has Generally Recognized as Safe (GRAS) status in the US (4912).
POSSIBLY SAFE ...when used orally and appropriately in medicinal amounts (2,4,6,12,18). Horseradish has been used with apparent safety at a dose of 480 mg daily for 12 weeks (96309). ...when topical preparations containing no more than 2% mustard oil, a constituent of horseradish, are used (2).
CHILDREN: LIKELY UNSAFE
when used orally in children less than 4 years of age because it can cause gastrointestinal problems (2,12,19).
PREGNANCY AND:
CHILDREN: LIKELY SAFE
when the root is used orally in amounts commonly found in foods.
Horseradish has Generally Recognized as Safe (GRAS) status in the US (4912).
CHILDREN: LIKELY UNSAFE
when the tincture is used regularly and in large amounts, as it is considered an abortifacient (19).
LACTATION: LIKELY SAFE
when the root is used orally in amounts commonly found in foods.
Horseradish has Generally Recognized as Safe (GRAS) status in the US (4912).
LACTATION: LIKELY UNSAFE
when used orally in large amounts.
The mustard oils produced by glucosinolates from horseradish are considered toxins that can be excreted through breast milk (33031).
Below is general information about the interactions of the known ingredients contained in the product Horseradish 500 mg Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, horseradish might interfere with the effects of thyroid hormone.
Details
Horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function (4).
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Below is general information about the adverse effects of the known ingredients contained in the product Horseradish 500 mg Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, horseradish is generally well tolerated when consumed in amounts commonly used with foods.
But consuming large amounts of horseradish can cause various adverse effects.
Most Common Adverse Effects:
Orally: When consumed in large amounts, bloody vomiting, diarrhea, gastrointestinal upset.
Topically: Fresh horseradish can cause irritation or allergic reaction.
Serious Adverse Effects (Rare):
Orally: Transient vasovagal syncope.
Dermatologic ...Topically, skin contact with fresh horseradish can cause irritation (4,19) or allergic reaction (4).
Endocrine ...Orally, horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function (4).
Gastrointestinal ...Orally, consuming large amounts of horseradish can cause gastrointestinal upset, bloody vomiting and diarrhea (2,6), and irritation of mucous membranes (2,4).
Genitourinary ...Orally, consuming large amounts of horseradish can cause irritation of the urinary tract (19).
Neurologic/CNS ...Orally, consuming large amounts of horseradish can cause vasovagal syncope in rare cases. At least two cases of vasovagal syncope associated with horseradish consumption have been reported. In one case, a 56-year-old male experienced a sharp burning sensation in his stomach followed by tachycardia, weakness, and excessive perspiration after consuming an oyster topped with an olive-sized dollop of fresh horseradish. He experienced vasovagal syncope within 5 minutes of horseradish ingestion but regained consciousness moments later, with few residual symptoms and no medical intervention required. Researchers theorize that the vapors from horseradish can irritate the gastric or respiratory tract mucosa triggering the vaso-vagal response. Horseradish-induced vasovagal syncope has also been referred to as Seder syncope due to the tradition of consuming bitter herbs, including horseradish, during the Jewish Passover holiday dinner. To reduce the potential for this reaction, researchers suggest that freshly prepared horseradish rest before consumption, allowing some of the active vapor ingredient, thought to be isothiocyanate, to evaporate before ingestion (111724).