Each tablet contains: Abrus Cantoniensis 5:1 extract (DHE 140 mg) 28 mg • Lysimachia Christinae 5:1 extract (DHE: 370 mg) 74 mg • Poria cocos 5:1 extract (DHE: 120 mg) 24 mg • Pyrrosia Lingua 5:1 extract (DHE: 120 mg) 24 mg • Zea Mays 5:1 extract (DHE: 250 mg) 50 mg. Other Ingredients: Corn Starch.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
Below is general information about the effectiveness of the known ingredients contained in the product Christina Liver Support. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Christina Liver Support. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Corn silk, corn silk extract, and corn silk oil has Generally Recognized as Safe (GRAS) status in the US (4912). There is insufficient reliable information available about the safety of corn silk when used orally as medicine.
PREGNANCY: POSSIBLY SAFE
when consumed in food.
PREGNANCY: LIKELY UNSAFE
when used orally in larger amounts because it might have uterine stimulant effects (4); avoid using.
LACTATION: POSSIBLY SAFE
when consumed in food amounts.
Insufficient reliable information available when used as medicine; avoid using.
There is insufficient reliable information available about the safety of poria mushroom.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Christina Liver Support. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
In an animal diabetic model, corn silk extract reduced levels of fasting blood glucose (103365). Theoretically, corn silk might have an additive effect with antidiabetes drugs and cause hypoglycemia.
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Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
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In clinical research, corn silk extract reduced systolic and diastolic blood pressure in both hypertensive and non-hypertensive individuals (93869). Taking corn silk extract with antihypertensive drugs might increase the risk for hypotension (4).
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In clinical research, corn silk extract increases the urinary excretion of potassium (93869). Theoretically, taking corn silk might have additive effects with drugs that deplete potassium, including corticosteroids (4).
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Overuse of corn silk might compound diuretic-induced potassium loss (4). In human research, corn silk extract increases the volume of urine and increases the excretion of sodium and potassium (93869). There is some concern that people taking corn silk along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
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Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation (19).
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Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
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In animal research, poria mushroom essential oil reduces acetylcholinesterase activity (111917). This interaction has not been shown in humans.
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Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
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In animal research, poria mushroom essential oil reduces acetylcholinesterase activity (111917). This interaction has not been shown in humans.
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Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
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Animal research shows that poria mushroom extract has sedative properties (111916). This interaction has not been shown in humans.
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Below is general information about the adverse effects of the known ingredients contained in the product Christina Liver Support. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, corn silk seems to be well tolerated. However, a thorough evaluation of safety outcomes associated with medicinal use has not been conducted (103362). Corn silk has been reported to cause hypokalemia with prolonged use (4). Topically, corn silk can cause contact dermatitis and urticaria (4).
Dermatologic ...Topically, corn silk can cause dermatitis and urticaria (4).
Endocrine ...Orally, corn silk has been reported to cause hypokalemia with prolonged use (4).
Renal ...Orally, corn silk extract can increase urinary volume and increase the excretion of sodium and potassium (93869).
General ...Orally, poria mushroom seems to be well tolerated. However, a thorough evaluation of safety outcomes has not been conducted.
Immunologic ...Allergic reactions have been reported rarely, including allergic rhinitis and allergic asthma (12).
