Vinca rosea 12 CH. Other Ingredients: Lactose, Sucrose.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
This is a homeopathic preparation. Homeopathy is a system of medicine established in the 19th century by a German physician named Samuel Hahnemann. Its basic principles are that "like treats like" and "potentiation through dilution." For example, in homeopathy, diarrhea would be treated with an extreme dilution of a substance that normally causes diarrhea when taken in high doses.
Practitioners of homeopathy believe that more dilute preparations are more potent. Many homeopathic preparations are so diluted that they contain little or no active ingredient. Therefore, most homeopathic products are not expected to have any pharmacological effects, drug interactions, or other harmful effects. Any beneficial effects are controversial and cannot be explained by current scientific methods.
Dilutions of 1 to 10 are designated by an "X." So a 1X dilution = 1:10, 3X=1:1000; 6X=1:1,000,000. Dilutions of 1 to 100 are designated by a "C." So a 1C dilution = 1:100; 3C = 1:1,000,000. Dilutions of 24X or 12C or more contain zero molecules of the original active ingredient.
Homeopathic products are permitted for sale in the US due to legislation passed in 1938 sponsored by a homeopathic physician who was also a Senator. The law still requires that the FDA allow the sale of products listed in the Homeopathic Pharmacopeia of the United States. However, homeopathic preparations are not held to the same safety and effectiveness standards as conventional medicines. For more information, see the Homeopathy monograph.
Below is general information about the effectiveness of the known ingredients contained in the product Vinca Rosea (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of Madagascar periwinkle.
Below is general information about the safety of the known ingredients contained in the product Vinca Rosea (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY UNSAFE ...when the plant or root are used orally. Madagascar periwinkle contains toxic vinca alkaloids, which can cause death (6). There is insufficient reliable information available about the safety of Madagascar periwinkle when used topically.
PREGNANCY: LIKELY UNSAFE
when used orally.
Madagascar periwinkle has abortifacient and teratogenic properties (19).
LACTATION: LIKELY UNSAFE
when used orally (6); avoid using.
Below is general information about the interactions of the known ingredients contained in the product Vinca Rosea (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Animal research shows that Madagascar periwinkle lowers blood glucose levels in diabetic rats (104764). Theoretically, using Madagascar periwinkle in combination with antidiabetes drugs might increase the risk of hypoglycemia; monitor blood glucose closely.
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Madagascar periwinkle is thought to have diuretic properties (6). Theoretically, due to these potential diuretic effects, Madagascar periwinkle might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
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Below is general information about the adverse effects of the known ingredients contained in the product Vinca Rosea (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, Madagascar periwinkle is generally regarded as unsafe for use.
Any benefits of therapy may not outweigh the risk of toxicity. Madagascar periwinkle can cause hallucinations, seizures, gastrointestinal upset, hepatotoxicity, and alopecia (17). The vinca alkaloid constituents of Madagascar periwinkle have been reported to cause nausea, vomiting, alopecia, dizziness, nystagmus, vertigo, hearing impairment, leukopenia, thrombocytopenia, bleeding, hyperuricemia, neurotoxicity, and possibly death (6,15).
Exposure to the airborne pollen of Madagascar periwinkle can cause respiratory allergic reactions in sensitive individuals (100665).
Dermatologic ...Orally, Madagascar periwinkle can cause alopecia (17).
Gastrointestinal ...Orally, Madagascar periwinkle can cause gastrointestinal upset (17). The vinca alkaloid constituents of Madagascar periwinkle have been reported to cause nausea and vomiting (6,15).
Hematologic ...Orally, the vinca alkaloid constituents of Madagascar periwinkle have been reported to cause leukopenia, thrombocytopenia, bleeding, and hyperuricemia (6,15).
Hepatic ...Orally, Madagascar periwinkle can cause hepatotoxicity (17).
Immunologic ...Exposure to the airborne pollen of Madagascar periwinkle can cause allergic respiratory reactions. In one population of adults with respiratory allergies, 29.8% tested positive to Madagascar periwinkle pollen during skin prick testing (100665).
Neurologic/CNS ...Orally, Madagascar periwinkle can cause hallucinations and seizures (17). The vinca alkaloid constituents of Madagascar periwinkle have been reported to cause dizziness, vertigo, and neurotoxicity (6,15).
Ocular/Otic ...Orally, the vinca alkaloid constituents of Madagascar periwinkle have been reported to cause nystagmus and hearing impairment (6,15).
