Conium Maculatum 9 CH • Natrum muriaticum 9 CH • Onosmodium Virginianum 7 CH, 9 CH, 12 CH • Physostigma Venenosum 9 CH • Pilocarpus 9 CH • Ruta 12 CH • Ruta graveolens 7 CH, 9 CH. Other Ingredients: Distilled Water, Ethyl Alcohol.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
This is a homeopathic preparation. Homeopathy is a system of medicine established in the 19th century by a German physician named Samuel Hahnemann. Its basic principles are that "like treats like" and "potentiation through dilution." For example, in homeopathy, diarrhea would be treated with an extreme dilution of a substance that normally causes diarrhea when taken in high doses.
Practitioners of homeopathy believe that more dilute preparations are more potent. Many homeopathic preparations are so diluted that they contain little or no active ingredient. Therefore, most homeopathic products are not expected to have any pharmacological effects, drug interactions, or other harmful effects. Any beneficial effects are controversial and cannot be explained by current scientific methods.
Dilutions of 1 to 10 are designated by an "X." So a 1X dilution = 1:10, 3X=1:1000; 6X=1:1,000,000. Dilutions of 1 to 100 are designated by a "C." So a 1C dilution = 1:100; 3C = 1:1,000,000. Dilutions of 24X or 12C or more contain zero molecules of the original active ingredient.
Homeopathic products are permitted for sale in the US due to legislation passed in 1938 sponsored by a homeopathic physician who was also a Senator. The law still requires that the FDA allow the sale of products listed in the Homeopathic Pharmacopeia of the United States. However, homeopathic preparations are not held to the same safety and effectiveness standards as conventional medicines. For more information, see the Homeopathy monograph.
Below is general information about the effectiveness of the known ingredients contained in the product Visuex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
There is insufficient reliable information available about the effectiveness of hemlock.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Visuex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
UNSAFE ...when used orally (6338). All parts of hemlock including seeds, flowers, and fruits are considered poisonous (6338,6339). Death has resulted after ingestion of hemlock (6340,54711). Damage to the tubule cells of the kidneys (acute tubular necrosis), rapid breakdown of muscle tissue and release of muscle tissue byproducts into the blood (rhabdomyolysis), and subsequent kidney failure, as well as respiratory arrest, have also been reported following ingestion of hemlock (54709,54716,54718,54727). Prompt medical attention is advised after ingestion of hemlock (6341).
CHILDREN: UNSAFE
when used orally (6340).
Acute, sometimes lethal poisoning has resulted after ingestion of leaf material (6340) or when hollow stems are used as peashooters, flutes, or whistles (6338).
PREGNANCY AND LACTATION: UNSAFE
when used orally because ingestion can be lethal (6338); avoid using.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Rue and rue oil have Generally Recognized as Safe (GRAS) status for use in foods at concentrations that do not exceed 2 parts per million (ppm) (12,4912).
POSSIBLY SAFE ...when products containing dried rue leaves are used medicinally in appropriate doses (6,12,18,515). However, therapeutic doses can cause drowsiness, dizziness, and gastrointestinal irritation and cramps (12).
LIKELY UNSAFE ...when fresh rue and rue oil are used orally, or when large doses of the dried herb are used orally (2,12,18). Overdose is associated with severe abdominal pain, vomiting, liver damage, kidney damage, vertigo, respiratory distress, and delirium, and can be fatal (12,18). ...when fresh rue is applied topically. Rue can cause contact dermatitis and severe photodermatitis (2,6,11,19,104119,107948).
PREGNANCY: LIKELY UNSAFE
when used orally.
Rue has uterine stimulant and abortifacient effects (12,19); avoid using. Deaths have been reported in women who used rue as an abortifacient (2).
LACTATION:
There is insufficient reliable information available about the use of rue when breast-feeding; avoid use.
Below is general information about the interactions of the known ingredients contained in the product Visuex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, taking calabar bean might reduce the effects of anticholinergic drugs.
Details
Physostigmine, a constituent of calabar bean, reverses the effects of belladonna and other drugs with anticholinergic activity (15).
|
Theoretically, rue might increase the risk for phototoxicity when used with photosensitizing drugs.
Details
|
Below is general information about the adverse effects of the known ingredients contained in the product Visuex. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, calabar bean can be unsafe.
Physostigmine, a constituent of calabar bean, can cause cholinergic crisis, including death.
Most Common Adverse Effects:
Oral: Bradycardia, diarrhea, miosis, hypertension, hypotension, salivation, sweating, tachycardia, vomiting.
Serious Adverse Effects (Rare):
Oral: Confusion, coma, muscle weakness, paralysis, seizures.
Cardiovascular ...Orally, calabar bean can cause bradycardia, tachycardia, hypotension, and hypertension (15).
Gastrointestinal ...Orally, calabar bean can cause diarrhea and vomiting (15).
Musculoskeletal ...Orally, calabar bean can cause muscle weakness and paralysis (15).
Neurologic/CNS ...Orally, calabar bean can cause confusion and coma (15).
Ocular/Otic ...Orally, calabar bean can cause miosis (15).
Other ...Orally, physostigmine, a constituent of calabar bean, can cause cholinergic crisis, including paralysis, coma, and death. Other symptoms of cholinergic crisis may include bradycardia, confusion, diarrhea, miosis, muscle weakness, salivation, sweating, and vomiting (15).
General ...Hemlock is generally regarded as unsafe for use. Any benefits of therapy may not outweigh the risk of toxicity. Orally, hemlock can cause burning of the mouth, throat, and abdomen, nausea, vomiting, excessive urination, salivation, drowsiness, mydriasis, muscle pain, rapid muscle swelling and stiffness, rhabdomyolysis, and tachycardia followed by bradycardia. It can also cause loss of speech, paralysis, encephalopathy, unconsciousness, rapid respiration and respiratory arrest, cardiovascular collapse, renal toxicity, and death (6340,6341,54709,54711,54712,54716,54717,54718,96877,96878).
Cardiovascular
...Orally, hemlock can cause tachycardia followed by bradycardia, cardiovascular collapse, and death (6340,6341,54712,96877).
In one case report, a 6-year old girl had prolonged coagulation tests after accidental ingestion of hemlock (96877). It can also cause hypertension (110410).
Intravenously, hemlock resulted in a brief cardiac arrest followed by return of spontaneous circulation in one case report (96876).
Gastrointestinal ...Orally, hemlock causes burning of the mouth, throat, and abdomen (6341,96877). It can also cause nausea, vomiting, and increased salivation (54712,96878,110410).
Genitourinary ...Orally, hemlock can cause excessive urination (54712).
Musculoskeletal ...Orally, hemlock can cause muscle pain, rapid muscle swelling and stiffness, and rhabdomyolysis (6340,6341,54712,110410). Plasma exchange effectively improved the signs of rhabdomyolysis in one case of hemlock poisoning (54727).
Neurologic/CNS
...Orally, hemlock can cause drowsiness, fatigue, lethargy, dizziness, numbness, loss of speech, tremors, paralysis, seizures, encephalopathy, unconsciousness, and death (6340,6341,10778,54711,54712,54716,96877,110410).
Death from hemlock toxicity is usually due to respiratory paralysis (96879,96877).
A case report describes prolonged status epilepticus in a 41-year-old, previously healthy female who mistook hemlock root for parsnip. She developed severe vomiting and drowsiness, followed by prolonged status epilepticus which was refractory to multiple drugs. Seizures and the abnormal electroencephalogram were ultimately controlled with thiopental, gradually weaning to long-term oral treatment with lacosamide and perampanel, which returned the patient to her baseline level of functioning (110411).
Ocular/Otic ...Orally, hemlock can cause blurred vision and mydriasis (54712,110410).
Pulmonary/Respiratory ...Orally, hemlock can cause rapid respiration (54712) as well as acute respiratory arrest (54709,96878). In one case report, a 45-year old woman required mechanical ventilation after accidental ingestion of hemlock (96878). Death from hemlock toxicity is usually due to respiratory paralysis (96876,96877).
Renal ...Orally, hemlock has been reported to cause myoglobinuria, acute tubular necrosis, and acute renal failure (54716,54717,54718,54728). Plasma exchange effectively improved the signs of renal failure in one case of hemlock poisoning (54727).
General
...Orally, rue is well tolerated when taken in the amounts found in foods.
The dried herb seems to be generally well tolerated when taken in medicinal doses; however, a thorough evaluation of safety outcomes has not been conducted. Fresh rue is generally considered unsafe.
Most Common Adverse Effects:
Orally: Cramps, drowsiness, depression, dizziness, gastrointestinal irritation, and sleep disturbances with medicinal use of the dried herb.
Topically: Contact dermatitis and phototoxic skin reactions with the fresh plant.
Cardiovascular ...Orally, large doses of rue have been associated with bradycardia (2).
Dermatologic ...Topically, rue can cause contact dermatitis (2). Exposure to the fresh rue plant followed by sun exposure within 48 hours can lead to severe phototoxic reactions (2,6). Multiple case reports describe patients who developed pruritus, erythema, and severe blistering on the back of the hands and wrists, equivalent to a partial thickness burn, after contact with the fresh plant leaves and exposure to sunlight (104119,107948). One patient was successfully treated with cetirizine and oral and topical corticosteroids (107948).
Gastrointestinal ...Orally, rue can cause gastrointestinal irritation and cramps at therapeutic doses (2,12). When taken in large doses, it causes severe abdominal pain and vomiting (2,12,18).
Genitourinary ...Orally, rue can cause uterine stimulation and abortion (2).
Hepatic ...Orally, high doses of rue can cause liver damage (2,12,18).
Neurologic/CNS ...Orally, therapeutic doses of rue can cause tremor, dizziness, drowsiness, sleep disorders, and depression. High doses can cause vertigo, seizures, and delirium (2,12,18).
Pulmonary/Respiratory ...Orally, high doses of rue can cause respiratory distress (2,12,18).
Renal ...Orally, high doses of rue can cause kidney damage (2,12,18).