Proprietary Blend: Gum Arabic , Rosemary , Yacon , Agave , Rose , Neroli , Ylang Ylang , Geranium . Other Ingredients: Purified Water.
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Below is general information about the effectiveness of the known ingredients contained in the product HYDRessence Rainmaker. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product HYDRessence Rainmaker. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY UNSAFE ...when fresh agave is used topically. Exposure to agave can cause localized swelling and redness, the formation of red, purple, or black skin lesions, and inflammation of small blood vessels (leukocytoclastic vasculitis) within minutes to hours of exposure (26144,26145). The most irritating portion of the plant appears to be the sap, although irritants may also be present in the leaves, stem, flowers, roots, and bulbs (26144). There is insufficient reliable information available about the safety of agave when used orally.
PREGNANCY: LIKELY UNSAFE
when used orally.
Agave contains constituents that may be uterine stimulants, and it has traditionally been used to induce labor (20017).
LACTATION:
Insufficient reliable information available; avoid using.
LIKELY SAFE ...when used orally and appropriately in amounts commonly found in foods. Gum arabic has Generally Recognized As Safe (GRAS) status for use in foods in the US. It is also considered to be safe for use as a food additive by the European Food Safety Authority (4912,105040).
POSSIBLY SAFE ...when used orally and appropriately in medicinal amounts (8072). Up to 30 grams daily of powdered gum arabic has been used with apparent safety for 3 months (18237,99098,105040).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using in amounts greater than those found in foods (4912,105040).
LIKELY SAFE ...when used orally in amounts typically found in foods. Rosemary has Generally Recognized as Safe (GRAS) status in the US (4912).
POSSIBLY SAFE ...when the leaf is used orally and appropriately in medicinal amounts (18). Powdered rosemary leaf has been used with apparent safety as a single dose of up to 1.5 grams (18246,91731) or at a dose of 1-4 grams daily for up to 8 weeks (91727,98536,105327,109561). ...when the essential oil is used topically and appropriately for up to 7 months (5177,91729,109560). ...when the essential oil is used by inhalation as aromatherapy, short-term (7107,18323,105324,109559).
LIKELY UNSAFE ...when the essential oil or very large quantities of rosemary leaf are used orally. Ingestion of undiluted rosemary oil or very large quantities of rosemary leaf can cause serious adverse effects (18,515).
PREGNANCY: POSSIBLY UNSAFE
when used orally in medicinal amounts.
Rosemary might have uterine and menstrual flow stimulant effects (4,12,18), and might increase metabolism of estradiol and estrone (18331); avoid using. There is insufficient reliable information available about the safety of rosemary when used topically during pregnancy.
LACTATION:
There is insufficient reliable information available about the safety of using rosemary in medicinal amounts during lactation; avoid using.
LIKELY SAFE ...when used in amounts commonly found in foods. Ylang ylang oil has Generally Recognized as Safe (GRAS) status in the US (4912). There is insufficient reliable information available about the safety of ylang ylang oil when used orally or topically in medicinal amounts.
CHILDREN: LIKELY SAFE
when used orally in amounts commonly found in food.
Ylang ylang oil has Generally Recognized as Safe (GRAS) status in the US (4912).
CHILDREN: POSSIBLY SAFE
when used topically.
Ylang ylang oil has been used with apparent safety as three applications to the scalp at 5-day intervals (13483). There is insufficient reliable information available about the safety of ylang ylang oil when used orally in medicinal amounts in children.
PREGNANCY AND LACTATION: LIKELY SAFE
when used orally in amounts commonly found in food.
Ylang ylang oil has Generally Recognized as Safe (GRAS) status in the US (4912). There is insufficient reliable information available about the safety of using ylang ylang oil in medicinal amounts.
Below is general information about the interactions of the known ingredients contained in the product HYDRessence Rainmaker. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Gum arabic can reduce the absorption of amoxicillin.
Details
A small study in healthy volunteers shows that taking amoxicillin and gum arabic concurrently significantly reduces the absorption of amoxicillin. Separate doses of amoxicillin from gum arabic by at least 2 hours (12654).
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Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Details
Gum arabic has been used as a suspending osmotic agent in drug formulations. It might improve bioavailability of water-insoluble drugs like naproxen, but reduce absorption of polar drugs like amoxicillin (12654,104058). To avoid changes in absorption, take gum arabic 30-60 minutes after oral medications.
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Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Details
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Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Details
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models (71821,71923). However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults (105327), no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs (105323,105327).
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Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Details
Rosemary is reported to contain salicylates (18330).
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Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Details
Rosemary is reported to contain salicylate (18330).
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Theoretically, rosemary might decrease the levels and clinical effects of CYP1A1 substrates.
Details
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Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Details
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Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Details
Rosemary is reported to contain salicylate (18330).
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Below is general information about the adverse effects of the known ingredients contained in the product HYDRessence Rainmaker. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Topically, agave may be unsafe.
There is currently a limited amount of information on the adverse effects of oral agave. A thorough evaluation of safety outcomes has not been conducted.
Most Common Adverse Effects:
Topically: Dermatitis.
Serious Adverse Effects (Rare):
Topically: Leukocytoclastic vasculitis.
Dermatologic ...There are reports of acute irritant contact dermatitis due to agave exposure, especially to the sap (19626,19627,26145,20014,20015). Oxalic acid crystals in the sap may be the cause of this irritation (20015). Treatment with oral antihistamines and topical saline compresses have been shown to reduce skin lesions following agave exposure within 7-10 days (19622,19623).
Gastrointestinal ...A case report describes a patient who developed a bezoar from eating agave (20021).
Other ...Exposure to agave can cause localized swelling and redness, the formation of red, purple, or black skin lesions, and inflammation of small blood vessels (leukocytoclastic vasculitis) within minutes to hours of exposure (26144,26145).
General
...Orally, gum arabic seems to be generally well tolerated.
Most Common Adverse Effects:
Orally: Abdominal bloating, flatulence, mild diarrhea, nausea, and vomiting.
Gastrointestinal ...Orally, gum arabic can cause minor gastrointestinal disturbances such as abdominal bloating, flatulence, nausea, vomiting, cramping, and mild diarrhea (8072,18237,99098,105038,105040,108051). These effects occurred in 15%, 82%, and 90% of subjects respectively in one study (18237). They may subside with continued use within 2 weeks (8072,18237,99098,105038).
Immunologic ...Gum arabic might cause allergic reactions. In one case report, a patient had an immunoglobulin E response after exposure to gum arabic. However, there have been no identified case reports of allergic reactions after oral exposure to gum arabic (19636,105040).
General ...Orally, rosemary seems to be well tolerated when used in appropriate medicinal amounts. Undiluted rosemary oil or very large quantities of rosemary leaf should not be consumed. Topically and as aromatherapy, rosemary seems to be well tolerated.
Dermatologic ...Topically, rosemary use can lead to photosensitivity, erythema, dermatitis, and cheilitis in hypersensitive individuals (4,6).
Immunologic
...Topically, allergic reactions can occur.
When used in the mouth, lip and gum edema have occurred (101173). When used on the skin, allergic contact dermatitis has occurred, likely due to the constituent carnosol (71715,71924,71926).
Rosemary might also cause occupational asthma. A case of occupational asthma caused by several aromatic herbs including thyme, rosemary, bay leaf, and garlic has been reported. The diagnosis was confirmed by inhalation challenges. Although all of the herbs caused immediate skin reactivity, a radioallergosorbent test (RAST) showed that garlic was the most potent allergen by weight, with rosemary and the other herbs showing less reactivity (783).
Neurologic/CNS ...Orally, the undiluted oil, as well as the camphor constituent of rosemary, might cause seizures (4,5,6,12868).
General
...There is currently a limited amount of information on the adverse effects of ylang ylang oil.
A thorough evaluation of safety outcomes has not been conducted.
Most Common Adverse Effects:
Topically: Dermatitis, pruritus.
Dermatologic ...Topically, ylang ylang oil in combination with other herbs can cause localized pruritus (13483).
Immunologic ...Topically, ylang ylang oil in combination with other herbs has caused contact dermatitis in various case reports (98615).