One capsule contains: DR1-Def brand Abdominal Cutting Complex 350 mg: Artemisia Dracunculus , Crape Myrtle (Banana leaf), Locoweed (Astragalus) • DR1-Test brand Muscle Conversion Complex 150 mg: Stinging Nettle leaf, 3,4-Divanillyltetrahydrofuran (95%), 19-nor-DHEA , 1-DHEA • Enhance Anabolic Absorption Complex 25 mg: Zinc Arginate Chelate , 6,7-Dihydroxybergamottin (DHB), Bioperine brand Black Pepper . Other Ingredients: Gelatin, Magnesium Stearate, Maltodextrin.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
Below is general information about the effectiveness of the known ingredients contained in the product DR1 Anabolic Steroid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient evidence about the effectiveness of 19-nor-DHEA.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product DR1 Anabolic Steroid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when banaba extract is used orally and appropriately, short-term (11954,92848,92849). A specific banaba extract (Glucosol) has been safely used at doses of 32-48 mg daily for 2 weeks (11954). Another specific product containing extracts of banaba leaf and Padang cassia (Inlacin, Dexa Medica) has been safely used at doses up to 100 mg daily for 12 weeks (92848,92849). There is insufficient reliable information available about the safety of banaba extract when used long-term.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
LIKELY SAFE ...when bergamot essential oil is used orally in amounts commonly found in foods. Bergamot oil has Generally Recognized As Safe (GRAS) status for use in foods in the US (4912).
POSSIBLY SAFE ...when bergamot extract is used orally, short-term. A bergamot extract (Bergamot Polyphenolic Fraction BPF, H&AD SRL) has been used with apparent safety at a dose of 650 mg daily for up to 120 days (96355,105318). Another bergamot extract providing 150 mg of flavonoids (Bergavit, Bionap) daily has been used with apparent safety for up to 6 months (102599). Bergamot phytosome (Vazguard, Indena SpA) has been used with apparent safety at a dose of 500 mg twice daily for 12 weeks (105317). ...when inhaled as aromatherapy, short-term. Bergamot oil 3% has been used with apparent safety as 2 drops poured on a cotton ball, attached to the collar, and breathed in for 20 minutes (105319).
POSSIBLY UNSAFE ...when used topically. Bergamot essential oil that is not free of furocoumarins or psoralens can act as a photosensitizer and can induce malignant changes (6,96370).
CHILDREN: LIKELY SAFE
when bergamot essential oil is used orally in amounts commonly found in foods.
Bergamot oil has Generally Recognized As Safe (GRAS) status for use in foods in the US (4912).
CHILDREN: POSSIBLY UNSAFE
when large amounts of the oil are ingested.
Bergamot essential oil can cause intestinal colic, convulsions, and death (12). There is insufficient reliable information available about the safety of bergamot extract when used orally.
PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when the oil is used topically (6).
There is insufficient reliable information available about the safety of bergamot when taken by mouth in medicinal amounts; avoid use.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Black pepper has Generally Recognized as Safe (GRAS) status in the US (4912).
POSSIBLY SAFE ...when black pepper oil is applied topically. Black pepper oil is nonirritating to the skin and is generally well tolerated (11). ...when black pepper oil is inhaled through the nose or as a vapor through the mouth, short-term. Black pepper oil as a vapor or as an olfactory stimulant has been used with apparent safety in clinical studies for up to 3 days and 30 days, respectively (29159,29160,29161,90502). There is insufficient reliable information available about the safety of black pepper when used orally in medicinal amounts.
CHILDREN: LIKELY SAFE
when used orally in amounts commonly found in foods (11).
CHILDREN: POSSIBLY UNSAFE
when used orally in large amounts.
Fatal cases of pepper aspiration have been reported in some patients (5619,5620). There is insufficient reliable information available about the safety of topical pepper oil when used in children.
PREGNANCY: LIKELY SAFE
when used orally in amounts commonly found in foods (11).
PREGNANCY: LIKELY UNSAFE
when used orally in large amounts.
Black pepper might have abortifacient effects (11,19); contraindicated. There is insufficient reliable information available about the safety of topical pepper when used during pregnancy.
LACTATION: LIKELY SAFE
when used orally in amounts commonly found in foods (11).
There is insufficient reliable information available about the safety of black pepper when used in medicinal amounts during breast-feeding.
UNSAFE ...when the leaf or seed are used orally or via inhalation (13,5622). Although all parts of the jimson weed plant contain toxic belladonna alkaloids, the seeds contain the highest quantity (5623). Ingestion of jimson weed can cause acute anticholinergic poisoning and death (17,5621,5622). The lethal dose for adults is 15-100 grams of jimson weed leaf or 15-25 grams of the seeds (equivalent to 100 mg atropine) (18).
CHILDREN: UNSAFE
when the seed or leaf are used orally or via inhalation.
Although all parts of the jimson weed plant contain toxic belladonna alkaloids, the seeds contain the highest quantity (5623). Ingestion of jimson weed can cause acute anticholinergic poisoning and death (17,5621,5622). Children are more sensitive to the toxic effects of jimson weed than adults, and the lethal dose is lower (18). The lethal dose in children is less than 1.5-10 grams of jimson weed leaf or less than 1.5-2.5 grams of the seeds (equivalent to 10 mg or less of atropine) (57144).
PREGNANCY AND LACTATION: UNSAFE
when used orally (2); avoid using.
POSSIBLY SAFE ...when used orally and appropriately. Stinging nettle root 360-600 mg has been used safely for up to 1 year (5093,11230,15195,76406,96744). ...when used topically and appropriately (12490).
PREGNANCY: LIKELY UNSAFE
when used orally due to possible abortifacient and uterine-stimulant effects (4,6,19).
LACTATION:
Insufficient reliable information available; avoid using.
LIKELY SAFE ...when the leaf or essential oil is used orally in amounts commonly found in foods. Tarragon has Generally Recognized as Safe (GRAS) status in the US (4912). There is insufficient reliable information available about the safety of tarragon when used orally or topically in medicinal amounts, or when used by inhalation for aromatherapy.
PREGNANCY AND LACTATION: LIKELY UNSAFE
Insufficient reliable information is available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product DR1 Anabolic Steroid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
19-nor-DHEA is purportedly converted to nandrolone and other androgens upon ingestion. Theoretically, taking 19-nor-DHEA with testosterone or other androgrens may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
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1-Androsterone is converted to 1-testosterone and other androgens upon ingestion (90399,91095). Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
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Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
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Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
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Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
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In vitro research shows that banaba inhibits OATP, particularly OATP2B1 (35450). OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.
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Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
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Animal research suggests that bergamot juice has hypoglycemic effects (34407).
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Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
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Theoretically, black pepper might increase the effects and side effects of amoxicillin.
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Animal research shows that taking piperine, a constituent of black pepper, with amoxicillin increases plasma levels of amoxicillin (29269). This has not been reported in humans.
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Theoretically, black pepper might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
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In vitro research shows that piperine, a constituent of black pepper, seems to inhibit platelet aggregation (29206). This has not been reported in humans.
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Theoretically, black pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
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Animal research shows that piperine, a constituent of black pepper, can reduce blood glucose levels (29225). Monitor blood glucose levels closely. Dose adjustments might be necessary.
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Theoretically, black pepper might increase blood levels of atorvastatin.
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Animal research shows that taking piperine, a constituent of black pepper, 35 mg/kg can increase the maximum serum concentration of atorvastatin three-fold (104188). This has not been reported in humans.
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Theoretically, black pepper might increase blood levels of carbamazepine, potentially increasing the effects and side effects of carbamazepine.
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One clinical study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that taking a single 20 mg dose of purified piperine, a constituent of black pepper, increases carbamazepine levels. Piperine may increase carbamazepine absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or inhibiting cytochrome P450 3A4 (CYP3A4) in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects (16833). In vitro research also shows that piperine can increase carbamazepine levels by 11% in a time-dependent manner (103819).
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Theoretically, black pepper might increase the effects and side effects of cyclosporine.
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In vitro research shows that piperine, a constituent of black pepper, increases the bioavailability of cyclosporine (29282). This has not been reported in humans.
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Theoretically, black pepper might increase levels of drugs metabolized by CYP1A1.
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In vitro research suggests that piperine, a constituent of black pepper, inhibits CYP1A1 (29213). This has not been reported in humans.
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Theoretically, black pepper might increase levels of drugs metabolized by CYP2B1.
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In vitro research suggests that piperine, a constituent of black pepper, inhibits CYP2B1 (29332). This has not been reported in humans.
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Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
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Theoretically, black pepper might increase levels of drugs metabolized by CYP3A4.
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Theoretically, black pepper might increase blood levels of lithium due to its diuretic effects. The dose of lithium might need to be reduced.
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Black pepper is thought to have diuretic properties (11).
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Black pepper might increase blood levels of nevirapine.
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Clinical research shows that piperine, a constituent of black pepper, increases the plasma concentration of nevirapine. However, no adverse effects were observed in this study (29209).
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Theoretically, black pepper might increase levels of P-glycoprotein substrates.
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Theoretically, black pepper might increase the sedative effects of pentobarbital.
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Animal research shows that piperine, a constituent of black pepper, increases pentobarbital-induced sleeping time (29214).
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Black pepper might increase blood levels of phenytoin.
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Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption, slow elimination, and increase levels of phenytoin (537,14442). Taking a single dose of black pepper 1 gram along with phenytoin seems to double the serum concentration of phenytoin (14375). Consuming a soup with black pepper providing piperine 44 mg/200 mL of soup along with phenytoin also seems to increase phenytoin levels when compared with consuming the same soup without black pepper (14442).
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Black pepper might increase blood levels of propranolol.
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Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of propranolol (538).
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Black pepper might increase blood levels of rifampin.
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Black pepper might increase blood levels of theophylline.
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Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of theophylline (538).
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Theoretically, jimson weed may increase anticholinergic effects and adverse effects.
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Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
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Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
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Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
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Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium (76402). The dose of lithium might need to be decreased.
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There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
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Stinging nettle contains a significant amount of vitamin K (19). When taken in large quantities, this might interfere with the activity of warfarin.
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Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion (49445,76932,77038). Theoretically, tarragon might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
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Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg (77024). Theoretically, concomitant use of tarragon with CNS depressants, including antihistamines, barbiturates, benzodiazepines, and tricyclic antidepressants, may increase sedative and other adverse effects.
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In vitro research suggests that tarragon extract inhibits monoamine oxidase (MAO)-A and MAO-B enzymes (106774). Theoretically, concomitant use with MAOIs might increase the effects and adverse effects associated with MAOIs.
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Below is general information about the adverse effects of the known ingredients contained in the product DR1 Anabolic Steroid. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...There is insufficient information available about adverse effects associated with 19-nor-DHEA. However, because It is purported that 19-nor-DHEA is metabolized to anabolic compounds. Therefore, there is concern that it might cause serious anabolic steroid-like side effects including stroke, kidney failure, and liver injury.
General ...Clinical evidence evaluating the safety of 1-androsterone is lacking. However, in one preliminary clinical study, low-density lipoprotein (LDL) cholesterol levels were increased and high-density lipoprotein (HDL) cholesterol levels were decreased. Some patients also developed indicators of liver and kidney damage. In these patients, the liver enzyme aspartate transaminase (AST) and serum creatinine were significantly increased (91095).
Cardiovascular ...Significant increases in LDL cholesterol of around 29 mg/dL and significant decreases in HDL cholesterol of around 19 mg/dL have been reported in patients taking 1-androsterone for 4-weeks (91095).
Hepatic ...Significant increases in AST of around 15. 4 IU/L have been reported in patients taking 1-androsterone daily for 4 weeks. Despite the elevation, average AST levels did not go much beyond 40 IU/L, the upper limit of normal for AST (91095).
Renal ...Significant increases in serum creatinine of around 0. 2 mg/dL and significant decreases in GFR of around 16.4 mL/min/1.72m2 have been reported in patients taking 1-androsterone for 4 weeks. Serum creatinine remained within normal range despite the elevation, GFR dropped below 89 mL/min/1.72m2, which is suggestive of renal impairment (91095).
General
...Orally, banaba extract appears to be well tolerated.
Most Common Adverse Effects:
Orally: Diaphoresis, dizziness, headache, palpitations, stomach upset, tremor, and weakness have been reported with a specific product containing extracts of banaba leaf and Padang cassia (Inlacin, Dexa Medica); however, it is unclear if these adverse effects were caused by banaba extract, Padang cassia, or the combination.
Cardiovascular ...Orally, palpitations have been reported with a specific product containing extracts of banaba leaf and Padang cassia (Inlacin, Dexa Medica); however, it is unclear if this adverse effect was caused by banaba extract, Padang cassia, or the combination (92848).
Gastrointestinal ...Orally, stomach upset has been reported with a specific product containing extracts of banaba leaf and Padang cassia (Inlacin, Dexa Medica); however, it is unclear if this adverse effect was caused by banaba extract, Padang cassia, or the combination (92849).
Neurologic/CNS ...Orally, dizziness, headache, tremor, and weakness have been reported with a specific product containing extracts of banaba leaf and Padang cassia (Inlacin, Dexa Medica); however, it is unclear if these adverse effects were caused by banaba extract, Padang cassia, or the combination (92848,92849).
Other ...Orally, diaphoresis has been reported with a specific product containing extracts of banaba leaf and Padang cassia (Inlacin, Dexa Medica); however, it is unclear if this adverse effect was caused by banaba extract, Padang cassia, or the combination (92849).
General
...Orally or as aromatherapy, bergamot seems to be well tolerated when used short-term.
Topically, bergamot is possibly unsafe.
Most Common Adverse Effects:
Topically: Blisters, erythema, photosensitivity, pigment spots, pustules, and skin lesions.
Dermatologic
...Frequent contact with the peel or oil of bergamot can cause erythema, blisters, pustules, dermatoses leading to scab formation, and pigment spots (18).
Topically, photosensitivity can also occur, especially in fair-skinned people (11019).
Gastrointestinal ...Orally, bergamot extract has been associated with one case of heartburn in clinical research (96356).
Musculoskeletal ...Orally, muscle cramps have been reported for a patient starting one week after switching from drinking 4 liters of black tea to drinking 4 liters of Earl Grey tea daily. The muscle cramps were attributed bergapten, a constituent of bergamot essential oil in Earl Grey tea. The patient's symptoms subsided after discontinuing Earl Grey tea intake and remained absent upon re-initiation of Earl Grey tea intake 1 liter daily (34344).
General
...Orally, black pepper seems to be well tolerated when used in the amounts found in food or when taken as a medicine as a single dose.
Topically and as aromatherapy, black pepper oil seems to be well tolerated.
Most Common Adverse Effects:
Orally: Burning aftertaste, dyspepsia, and reduced taste perception.
Inhalation: Cough.
Serious Adverse Effects (Rare):
Orally: Allergic reaction in sensitive individuals.
Gastrointestinal ...Orally, black pepper can cause a burning aftertaste (5619) and dyspepsia (38061). Single and repeated application of piperine, the active constituent in black pepper, to the tongue and oral cavity can decrease taste perception (29267). By intragastric route, black pepper 1.5 grams has been reported to cause gastrointestinal microbleeds (29164). It is not clear if such an effect would occur with oral administration.
Immunologic ...In one case report, a 17-month-old male developed hives, red eyes, facial swelling, and a severe cough following consumption of a sauce containing multiple ingredients. Allergen skin tests were positive to both black pepper and cayenne, which were found in the sauce (93947).
Ocular/Otic ...Topically, ground black pepper can cause redness of the eyes and swelling of the eyelids (5619).
Pulmonary/Respiratory ...When inhaled through the nose as an olfactory stimulant, black pepper oil has been reported to cause cough in one clinical trial (29162).
General
...Orally, jimson weed is unsafe.
Most Common Adverse Effects:
Orally: Anticholinergic effects, such as abdominal pain, altered mental status, dry eyes, dry mouth, dry skin, nausea, tachycardia, urinary retention, and vomiting.
Serious Adverse Effects (Rare):
Orally: Anticholinergic toxicity, death.
Cardiovascular ...Orally, jimson weed can cause anticholinergic side effects such as hypertension, tachycardia, and arrhythmia (57099,57156,57067,57103,57151,57152,57129,109502).
Dermatologic ...Orally, jimson weed can cause anticholinergic side effects such as dry, red, flushed, or hot skin and decreased perspiration (57089,57146).
Gastrointestinal ...Orally, jimson weed can cause anticholinergic side effects such as abdominal pain, nausea and vomiting, decreased bowel sounds, and difficulty swallowing (13,18,5623,109502).
Genitourinary ...Orally, jimson weed can cause anticholinergic side effects such as urinary retention (57129,57152,57151,109502).
Hematologic ...Orally, jimson weed has been reported to cause thrombocytopenia in one patient (109502).
Hepatic ...Orally, jimson weed can cause hepatotoxic events, including fulminant hepatitis (57091).
Musculoskeletal ...Orally, jimson weed can cause anticholinergic side effects such as leg cramps, muscle tremor, and muscle rigidity (57089,57146).
Neurologic/CNS ...Orally, jimson weed can cause anticholinergic side effects such as memory loss, attention impairment, confusion, hallucinations, slurred speech, psychosis, agitated delirium, seizures, and coma (57067,57075,57077,57078,57084,57085,57098,57103)(57108,57116,57120,57140,57148)(57151,57152,57156,109502).
Ocular/Otic ...Orally, jimson weed can cause anticholinergic side effects such as blurred vision and mydriasis (57120,57133,57151,57151,57116,57121,109502). Topically, direct exposure of the eye to jimson weed alkaloids can also cause mydriasis (57061).
Other
...Orally, jimson weed can block muscarinic cholinergic neurons and cause anticholinergic side effects.
Larger amounts of jimson weed intake can also lead to toxicity and anticholinergic syndrome. Central anticholinergic symptoms, which are dose-dependent, include muscle tremor and rigidity, leg cramps, hallucinations, slurred speech, psychosis, agitated delirium, seizures, coma, cardiovascular collapse, or respiratory failure. Peripheral anticholinergic symptoms include dilated pupils, blurry vision, dry mouth, flushed skin, tachycardia, arrhythmias, fever, hypertension or hypotension, and difficulty urinating (636,57067,57075,57077,57078,57084,57085,57098,57103)(57108,57116,57120,57140,57148)(57151,57152,57156). There are also numerous reports of death after jimson weed ingestion (5622,57067,57086,57088,109503). The lethal dose of jimson weed for adults is 15-100 grams of leaf or 15-25 grams of the seeds (equivalent to 100 mg atropine) (18). Jimson weed toxicity seems to occur 1-12 hours after ingestion (57084,57092,109502).
Children and adolescents are more susceptible to jimson weed toxicity. The lethal dose of atropine in this population is 10 mg or less. There are numerous case reports of anticholinergic toxicity in children and adolescents ingesting jimson weed seeds accidentally and recreationally (57098,57129,57144,95448,95449,95450,95451,95452). Some children ingested leaves that were packed into jimson weed cigarettes; others ingested several hundred seeds (57116).
General
...Orally, stinging nettle seems to be generally well tolerated.
Most Common Adverse Effects:
Orally: Constipation, diarrhea.
Topically: Contact with the raw plant causes itching, rash, and stinging.
Dermatologic ...Topically, fresh stinging nettle leaves and stalk can cause localized rash, itching, and stinging (12490,76399,76412,76414,76417,76428,76448,96746). Usually, short exposure to stinging nettle results in a transient urticarial reaction and a stinging sensation which may persist for more than 12 hours (76399,76414,76417,96746). In one report, a patient placed a fresh stinging nettle leaf on the tongue to suck out the sap of the leaf. Severe tongue edema, pain, and urticaria developed within 5 minutes. Symptoms continued for several hours after the leaf was removed (15197). In another case report, a young couple intoxicated with methamphetamine fell and laid in a stinging nettle bush for 20 minutes, after which urticaria and pain continued for 2-3 weeks, and a heightened sensitivity to cold persisted for several months (96746).
Endocrine
...A case of gynecomastia has been reported for a 33-year-old male who consumed stinging nettle tea 2 cups daily for one month prior to symptom onset.
The condition subsided one month after discontinuing stinging nettle tea (76410).
There have been two cases of galactorrhea associated with the consumption of stinging nettle for one month (76410,108902). In one case, a 33-year-old female consuming stinging nettle tea showed high levels of estradiol and low levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH). The levels of these hormones normalized 6 weeks after discontinuing stinging nettle tea (76410). In the other case report describing a 30-year-old female self-treating with stinging nettle 500 mg daily, hormone levels were not reported; however, a mammogram showed scattered areas of fibroglandular density and benign-appearing calcifications. This patient had complete resolution of symptoms 1 week after discontinuation of stinging nettle (108902).
Gastrointestinal ...Orally, stinging nettle root can cause gastrointestinal complaints, including diarrhea and constipation (1,7,11230). Stinging nettle above ground parts may cause mild gastrointestinal discomfort when taken on an empty stomach (7035). Stinging nettle juice may cause diarrhea (1). One patient taking a combination product containing stinging nettle root extract and pygeum bark extract (Prostatonin, Pharmaton) experienced continual gastrointestinal pain and hyperperistalsis. It is not clear if this effect was due to stinging nettle or pygeum (70230).
Genitourinary ...There is a case report of decreased ejaculatory volume associated with an herbal blend product containing stinging nettle root extract, saw palmetto extract, pumpkin seed oil extract, lemon bioflavonoid extract, and beta-carotene (5093). It is unclear if this was due to stinging nettle, other ingredients, or the combination.
Hepatic ...A case of idiosyncratic drug-induced liver disease (DILI) is reported in a 36-year-old female who presented with abdominal pain after 1 month of taking an herbal liver detox tea containing stinging nettle and other ingredients. Remarkable laboratory values included elevated liver enzymes, alkaline phosphatase, and total bilirubin. The patient received a loading dose of N-acetylcysteine and was hospitalized for 12 days (112178). However, it is unclear if the adverse effect was due to the stinging nettle, other ingredients, or the combination.
Other ...Orally, stinging nettle root can cause sweating (1,7).
General ...No adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted. There is concern that long-term consumption of estragole, a constituent of tarragon, increases the risk for cancer. However, this risk has only been shown in animals (77046,77029,77042).
