Liver Support Wasabia by Dr. LaMar's Products

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Cardiovascular disease (CVD). Although there has been interest in using oral wasabi to prevent CVD, there is insufficient reliable information about the clinical effects of wasabi for this purpose.
• Chronic fatigue syndrome (CFS). It is unclear if oral wasabi is beneficial for myalgic encephalomyelitis/chronic fatigue syndrome. Details: A very small open-label clinical study in adults with myalgic encephalomyelitis/chronic fatigue syndrome shows that taking a wasabi extract containing 3.2 mg of the 6-(methylsulfinyl) hexyl isothiocyanate constituent 3 times a day for 12 weeks modestly improves some scores related to fatigue and the frequency of myalgia and headache when compared to baseline (112845). However, the validity of this study is limited by the lack of a comparator group.
• Dyspepsia. Although there has been interest in using oral wasabi for dyspepsia, there is insufficient reliable information about the clinical effects of wasabi for this purpose.
• Fatigue. It is unclear if oral wasabi is beneficial for fatigue. Details: A small open-label clinical study in healthy adults experiencing fatigue shows that taking wasabi extract 600 mg (containing 4.8 mg of 6-(methylsulfinyl) hexyl isothiocyanate, a constituent of wasabi) daily for 4 weeks improves self-reported scores of fatigue and some factors related to mood when compared to baseline. Oral wasabi extract also improves self-reported scores regarding sleep (e.g., quality of sleep, sleepiness after rising) (112846). However, the validity of these findings is limited by the lack of a comparator group.
• Irritable bowel syndrome (IBS). Although there has been interest in using oral wasabi for IBS, there is insufficient reliable information about the clinical effects of wasabi for this purpose.
• Osteoporosis. Although there has been interest in using oral wasabi for osteoporosis, there is insufficient reliable information about the clinical effects of wasabi for this purpose. More evidence is needed to rate wasabi for these uses.

(Read more about WASABI)

LIKELY SAFE ...when used orally in food amounts (29994). When used orally and appropriately in medicinal amounts, short-term, wasabi extract 600 mg once daily has been safely used for up to 4 weeks (112846).

PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.

(Read more about WASABI)

ANTICOAGULANT/ANTIPLATELET DRUGS Interaction Rating = Moderate Be cautious with this combination. Severity = High •  Occurrence = Possible •  Level of Evidence = D Theoretically, wasabi might increase the risk of bleeding with anticoagulant or antiplatelet drugs.  Details In vitro research shows that 6-(methylsulfinyl) hexyl isothiocyanate, a constituent of wasabi, inhibits platelet aggregation (29143).

(Read more about WASABI)

General ...Orally, wasabi seems to be well tolerated in medicinal amounts.

Endocrine ...A small clinical study in adults taking oral wasabi extract 2000 mg once daily for 4 weeks has found 1 case of ketone bodies in the urine (112846).

Hepatic ...A small clinical study in adults taking oral wasabi extract 1000 mg once daily for 4 weeks has found 1 case of mildly elevated alanine transaminase and aspartate transaminase levels (112846).

Musculoskeletal ...A small clinical study in adults taking oral wasabi extract 2000 mg once daily for 4 weeks has found 1 case of elevated creatine phosphokinase (112846).

Renal ...A small clinical study in adults taking oral wasabi extract 1000 mg once daily for 4 weeks has found 2 cases of proteinuria (112846).

(Read more about WASABI)