Pro Extreme [Discontinued] by Xcel Sports Nutrition

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Athletic performance. Although there is interest in using oral 6-Bromo for athletic performance, there is insufficient reliable information about the clinical effects of 6-Bromo for this purpose.
• Erectile dysfunction (ED). Although there is interest in using oral 6-Bromo for ED, there is insufficient reliable information about the clinical effects of 6-Bromo for this condition.
• Muscle strength. Although there is interest in using oral 6-Bromo for muscle strength, there is insufficient reliable information about the clinical effects of 6-Bromo for this purpose.
• Obesity. Although there is interest in using oral 6-Bromo for obesity, there is insufficient reliable information about the clinical effects of 6-Bromo for this condition.
• Psychological well-being. Although there is interest in using oral 6-Bromo for psychological well-being, there is insufficient reliable information about the clinical effects of 6-Bromo for this purpose.
• Sexual arousal. Although there is interest in using oral 6-Bromo for sexual arousal, there is insufficient reliable information about the clinical effects of 6-Bromo for this purpose. More evidence is needed to rate 6-Bromo for these uses.

(Read more about 6-BROMO - [FAST FACTS])

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Athletic performance. Although there is interest in using oral epistane for athletic performance, there is insufficient reliable information about the clinical effects of epistane for this purpose.
• Erectile dysfunction (ED). Although there is interest in using oral epistane for ED, there is insufficient reliable information about the clinical effects of epistane for this purpose.
• Exercise-induced muscle damage. Although there is interest in using oral epistane for muscle recovery after exercise, there is insufficient reliable information about the clinical effects of epistane for this purpose.
• Muscle strength. Although there is interest in using oral epistane for increasing muscle strength, there is insufficient reliable information about the clinical effects of epistane for this purpose.
• Obesity. Although there is interest in using oral epistane for weight loss, there is insufficient reliable information about the clinical effects of epistane for this purpose.
• Psychological well-being. Although there is interest in using oral epistane for improving well-being, there is insufficient reliable information about the clinical effects of epistane for this purpose.
• Sexual arousal. Although there is interest in using oral epistane for increasing sexual arousal, there is insufficient reliable information about the clinical effects of epistane for this purpose. More evidence is needed to rate epistane for these uses.

(Read more about EPISTANE)

The effectiveness of methoxydienone is unknown.

(Read more about METHOXYDIENONE - [FAST FACTS])

The effectiveness of methylstenbolone is unknown.

(Read more about METHYLSTENBOLONE - [FAST FACTS])

POSSIBLY UNSAFE ...when used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromatase inhibitors are dangerous. Adverse effects associated with aromatase inhibitors include aggressive behavior, adrenal insufficiency, decreased rate of bone maturation and growth, decreased sperm production, infertility, kidney failure, and liver dysfunction (91094,102468).

PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromatase inhibitors are dangerous (91094). Avoid using.

(Read more about 6-BROMO - [FAST FACTS])

POSSIBLY UNSAFE ...when used orally. Anabolic androgenic steroids, such as epistane, can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, gynecomastia (in males), hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The US Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous (91094,109606,91138).

PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when used orally. Anabolic androgenic steroids, such as epistane, can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The US Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous (91094,109606,91138). Avoid using.

(Read more about EPISTANE)

POSSIBLY UNSAFE ...when used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, gynecomastia (in men), hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous (91094).

PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous (91094). Avoid using.

(Read more about METHOXYDIENONE - [FAST FACTS])

POSSIBLY UNSAFE ...when used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, gynecomastia (in men), hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous (91094).

PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous (91094). Avoid using.

(Read more about METHYLSTENBOLONE - [FAST FACTS])

(Read more about 6-BROMO - [FAST FACTS])

HEPATOTOXIC DRUGS Interaction Rating = Moderate Be cautious with this combination. Severity = High •  Occurrence = Possible •  Level of Evidence = D Theoretically, concomitant use might have additive adverse hepatotoxic effects.  Details Epistane is an anabolic androgenic steroid, and more specifically a 17-alpha-alkylated androgen. Therefore, there is concern that epistane has hepatotoxic effects (91138). Also, epistane is structurally similar to epitiostanol, which has been associated with hepatotixicity in a case series of four patients (109606).

(Read more about EPISTANE)

(Read more about METHOXYDIENONE - [FAST FACTS])

(Read more about METHYLSTENBOLONE - [FAST FACTS])

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(Read more about 6-BROMO - [FAST FACTS])

General ...A thorough evaluation of adverse effects has not been conducted. However, epistane is an anabolic androgenic steroid. This drug class is associated with cardiac, hepatic, and hormonal adverse effects.
Serious Adverse Effects (Rare): Hepatotoxicity.

Hepatic ...Epistane is an anabolic androgenic steroid, and more specifically a 17-alpha-alkylated androgen. Therefore, there is concern that epistane has hepatotoxic effects (91138). Also, epistane is structurally similar to epitiostanol, which was associated with hepatotoxicity in a case series of four patients. Use of epitiostanol was determined to be the probable cause of severe anabolic steroid-induced cholestasis, jaundice, and pruritus. These patients were unresponsive to standard treatments and required albumin dialysis with Molecular Adsorbent Recirculating System (MARS) (109606).

(Read more about EPISTANE)

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(Read more about METHOXYDIENONE - [FAST FACTS])

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(Read more about METHYLSTENBOLONE - [FAST FACTS])