Ingredients | Amount Per Serving |
---|---|
Nutrient Absorption Blend
|
200 mg |
(Aspergillus oryzae, Bacillus subtilis)
(Protease SP (Form: Bacillus sp. Genus: Bacillus Species: sp., A. oryzae Genus: A. Species: oryzae) Note: 97,000 HUT )
|
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(Aspergillus melleus)
(Protease S (Form: A. melleus Genus: A. Species: melleus) Note: 10,500 PC )
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(Aspergillus niger)
(Acid Protease (Form: A. niger Genus: A. Species: niger) Note: 10 SAPU )
|
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(Aspergillus niger, Candida rugosa, Rhizopus oryzae)
(Lipase (Form: C. rugosa Genus: C. Species: rugosa, R. oryzae Genus: R. Species: oryzae, A. niger Genus: A. Species: niger) Note: 4,000 FIP )
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Cellulase
(Trichoderma longibrachiatum)
(Cellulase (Form: T. longibrachiatum Genus: T. Species: longibrachiatum) Note: 2,400 CU )
|
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(Porcine)
(Trypsin (Form: Porcine) Note: 20,000 USP )
|
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(Trypsin)
(Chymotrypsin (Form: Porcine) Note: 3,336 USP )
|
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(Aspergillus niger)
(Phytase (Form: A. niger Genus: A. Species: niger) Note: 20 FTU )
|
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Beta-Glucanase
(Trichoderma longibrachiatum)
(Beta-Glucanase (Form: T. longibrachiatum Genus: T. Species: longibrachiatum) Note: 30 BGU )
|
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Hemicellulase
(Aspergillus niger)
(Hemicellulase (Form: A. niger Genus: A. Species: niger) Note: 4,000 HCU )
|
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Pectinase
(Aspergillus niger)
(Pectinase (Form: A. niger Genus: A. Species: niger) Note: 50 endo-PGU )
|
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Xylanase
(Trichoderma longibrachiatum)
(Xylanase (Form: T. longibrachiatum Genus: T. Species: longibrachiatum) Note: 600 XU )
|
Tapioca Maltodextrin, Vegetable Cellulose Note: capsule, Corn Maltodextrin, Medium Chain Triglycerides (Form: Coconut)
Below is general information about the effectiveness of the known ingredients contained in the product Extraordinary Enzymes. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Proteolytic enzymes represent a wide group of enzymes that are used alone or in combination. See specific monographs for effectiveness information.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Extraordinary Enzymes. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used ophthalmically, as approved by the US Food and Drug Administration (9).
POSSIBLY SAFE ...when used orally in combination with trypsin for up to 10 days (716). There is insufficient reliable information available about the safety of chymotrypsin when administered by other routes.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
There is insufficient reliable information available about the safety of lipase.
CHILDREN: POSSIBLY UNSAFE
when recombinant human bile salt-stimulated lipase (rhBSSL) is used orally by premature infants.
Adding rhBSSL to infant formula or pasteurized breast milk increases the risk for serious gastrointestinal adverse effects in premature infants (101940).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
LIKELY SAFE ...when consumed in the amounts commonly found in foods. There is insufficient reliable information available about the safety of phytase when used orally as a supplement.
PREGNANCY AND LACTATION:
Insufficient reliable information is available; avoid using.
POSSIBLY SAFE ...when used orally and appropriately. Various proteolytic enzymes have been safely used orally in clinical research (716,964,965,968,969,6252,6253,10622,11457,18281,18284) (91104,91105,91106,91111,96449). Side effects are typically mild to moderate and most often include gastrointestinal effects. See specific monographs for more detailed information related to the safety of individual proteolytic enzymes. ...when used topically and appropriately. Various proteolytic enzymes have been safely used topically in clinical research (67835,67843,67845,91113). Some proteolytic enzymes might cause allergic reactions when used topically. See specific monographs for more detailed information related to the safety of individual proteolytic enzymes.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
POSSIBLY SAFE ...when used topically by healthcare professionals trained in wound debridement (506). There is insufficient reliable information available about the safety of trypsin for its other uses. Although trypsin has been safely used in clinical research in doses of up to 288 mg orally daily in combination with other enzymes for up to 3 months, it is unclear if trypsin taken orally alone is safe (37193,92235,99473).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Extraordinary Enzymes. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the adverse effects of the known ingredients contained in the product Extraordinary Enzymes. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...There is currently a limited amount of information available about the adverse effects of chymotrypsin. Orally, hypersensitivity reactions, including anaphylaxis, have been reported (9). When injected into the eye, chymotrypsin has been reported to cause increased intraocular pressure and uveitis (9,509).
Immunologic ...Rarely, chymotrypsin has been reported to cause anaphylactic reactions characterized by dyspnea, urticaria, edema, shock, vascular collapse, and unconsciousness, which can lead to death (9,509).
Ocular/Otic ...Intraocular injections of chymotrypsin have been reported to cause increased intraocular pressure, corneal edema, striation, uveitis, iridoplegia, and filamentary keratitis (9,509).
General
...No adverse effects have been reported in adults.
However, a thorough evaluation of safety outcomes has not been conducted.
Serious Adverse Effects (Rare):
Orally: Gastrointestinal adverse effects, such as necrotizing enterocolitis, when recombinant human bile salt-stimulated lipase is used in premature infants.
Gastrointestinal ...Orally, when added to the formula or pasteurized breast milk consumed by premature infants, recombinant human bile salt-stimulated lipase (rhBSSL) can cause gastrointestinal adverse effects, including abdominal distension, flatulence, constipation, colic, abdominal pain, gastroenteritis, vomiting, regurgitation, and rectal bleeding (101940). Premature infants receiving rhBSSL also had a slightly higher rate of necrotizing enterocolitis (NEC) when compared with those receiving placebo. After review by a panel of experts, it was determined that the rate of confirmed or suspected NEC in infants consuming rhBSSL was 3.3%, compared with 0.5% in those receiving placebo. Although this rate of NEC is lower than the historical rate of occurrence in premature infants (11%), a possible increased risk for NEC cannot be ruled out (101940).
General ...Orally, no adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted. Workplace immunological responses to airborne powdered phytase have been reported (101901,101908,101909,101910).
Immunologic ...There are numerous reports of immunologic responses to airborne powdered phytase in the animal-feed industry (101901,101908,101909,101910). Examples of reactions include allergic occupational asthma and hypersensitivity pneumonitis (101901,101908). In one case report of a 43-year-old male, hypersensitivity pneumonitis related to phytase was diagnosed following a 6-month history of coughing, shortness of breath, fever, and dyspnea (101908). In an analysis of 53 people occupationally exposed to phytase, 28% had IgE antibodies and 45% had IgG antibodies specific to phytase. Symptoms included dyspnea, rhinitis, and eye and skin reactions (101909). In another analysis of patients with IgE-mediated occupational respiratory allergy, wheezing, chest tightness, shortness of breath, cough, and asthmatic symptoms were reported (101910).
General
...Orally, proteolytic enzymes are generally well tolerated.
See specific monographs for detailed safety information related to individual proteolytic enzymes.
Most Common Adverse Effects:
Orally: Gastrointestinal upset.
Serious Adverse Effects (Rare):
Topically: Allergic reactions.
Gastrointestinal ...Orally, some patients taking proteolytic enzymes may have gastrointestinal complaints (101517).
Immunologic ...Proteolytic enzymes are commonly found in laundry detergents and pre-spotter products. Rarely, protease specific IgE positive tests possibly related to these products have occurred. Exposure may be airborne or topical (102705). In addition, in case reports, occupational exposure to the airborne proteolytic enzyme pepsin has resulted in allergic rhinoconjunctivitis or asthma (102706,102707).
General ...Topically, trypsin can cause localized pain and transient burning (506). Orally, trypsin taken in combination with other enzymes can cause mild-to-moderate gastrointestinal symptom such as nausea, heartburn, and stomach pain (37193,92235). It is not known if trypsin or other enzymes causes these adverse effects.
Dermatologic ...Topically, trypsin can cause localized pain and transient burning (506).
Gastrointestinal ...Orally, trypsin taken in combination with other enzymes can cause mild-to-moderate gastrointestinal symptom such as nausea, heartburn, and stomach pain (37193,92235). It is not known if trypsin or other enzymes causes these adverse effects.