| Ingredients | Amount Per Serving |
|---|---|
|
(Prunus serotina )
(dried bark)
((Extraction rate: 330 mg of dry plant material per 1 mL.) (Origin: USA))
(certified organic Wild Cherry extract PlantPart: dried bark Genus: Prunus Species: serotina Note: (Extraction rate: 330 mg of dry plant material per 1 mL.) (Origin: USA) )
|
970 mg |
Vegetable Palm Glycerin, pharmaceutical grade Alcohol
Below is general information about the effectiveness of the known ingredients contained in the product Wild Cherry. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of wild cherry.
Below is general information about the safety of the known ingredients contained in the product Wild Cherry. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods and beverages. Wild cherry has Generally Recognized as Safe (GRAS) status in the US (4912).
POSSIBLY SAFE ...when used orally and appropriately short-term, in limited amounts (12).
POSSIBLY UNSAFE ...when used orally and long-term or in excessive amounts (12,19). The constituent prunasin hydrolyzes to hydrocyanic acid (HCN) (11,12,13,18).
PREGNANCY: LIKELY UNSAFE
when used orally because prunasin is potentially teratogenic (19).
LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Wild Cherry. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes (6450). Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
 Details
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.
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Below is general information about the adverse effects of the known ingredients contained in the product Wild Cherry. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, large amounts of wild cherry can lead to cyanide toxicity, which can be fatal (18,41565).
Neurologic/CNS ...Orally, large amounts of wild cherry can lead to cyanide toxicity, which can be fatal (18,41565). A case of accidental poisoning has been reported for a 56-year old women who consumed approximately 300 grams of wild cherries that had been steeped in alcohol the evening before symptom onset. The patient presented to the hospital the following day with symptoms including headache, nausea, vomiting, confusion, and severe dyspnea. Eventually the patient became comatose and hypotonic. After regaining consciousness the following day, the patient continued to experience severe sinus bradycardia, as well as disorientation, hallucinations, delusions, and agitation. After about 3 weeks, the patient began to experience blurred vision and tingling sensation of the lower limbs. The symptoms were eventually attributed to cyanide intoxication; the wild cherries the patient had consumed contained 4.7-15 mg/kg cyanide (41565).
