| Ingredients | Not Present |
|---|---|
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(Vinca major )
(flowering tips & leaf)
(Dry herb / menstruum ratio: 1:5)
(Periwinkle PlantPart: flowering tips & leaf Genus: Vinca Species: major Note: Dry herb / menstruum ratio: 1:5 )
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certified organic Grain Alcohol Note: 43-53%, distilled Water, Periwinkle extractives
Below is general information about the effectiveness of the known ingredients contained in the product Periwinkle. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of periwinkle.
Below is general information about the safety of the known ingredients contained in the product Periwinkle. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the interactions of the known ingredients contained in the product Periwinkle. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, taking periwinkle may increase the effects of antihypertensive drugs due to the hypotensive activity of vincamine, a constituent of periwinkle (12,19).
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Below is general information about the adverse effects of the known ingredients contained in the product Periwinkle. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Periwinkle is generally regarded as unsafe for use. Orally, periwinkle can cause cytotoxic, neurologic, liver, and kidney damage due to its vinca alkaloid constituents (17). Periwinkle has also been reported to cause gastrointestinal complaints, skin flushing, and hypotension (18).
Cardiovascular ...Orally, large amounts of periwinkle can cause a severe drop in blood pressure (18).
Dermatologic ...Orally, periwinkle can cause skin flushing (18).
Gastrointestinal ...Orally, periwinkle can cause gastrointestinal complaints (18).
Hepatic ...Orally, periwinkle can cause liver damage due to its vinca alkaloid constituents (17).
Neurologic/CNS ...Orally, periwinkle can cause neurologic damage due to its vinca alkaloid constituents (17).
Renal ...Orally, periwinkle can cause kidney damage due to its vinca alkaloid constituents (17).
