Ingredients | Amount Per Serving |
---|---|
(Illicium verum )
|
450 mg |
Vegetable Cellulose Capsules
Below is general information about the effectiveness of the known ingredients contained in the product Illicium Supreme 450 mg. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of star anise.
Below is general information about the safety of the known ingredients contained in the product Illicium Supreme 450 mg. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Star anise has Generally Recognized as Safe (GRAS) status in the US (4912).
POSSIBLY UNSAFE ...when star anise is used orally as a tea. In 2003, the US Food and Drug Administration (FDA) issued an advisory to the public not to consume teas brewed from star anise. They have been associated with adverse neurological and gastrointestinal effects, including jitteriness, irritability, tachycardia, nystagmus, vomiting, diarrhea, and seizures. Star anise products associated with these symptoms are often found to be contaminated with Japanese star anise (Illicium anisatum), which has known toxicity (11384,13058,76290,76293,100159,108932). However, large doses of star anise can also cause neurotoxicity (108932).
CHILDREN: POSSIBLY UNSAFE
when used orally.
Star anise tea is a traditional remedy for infant colic, but has been associated with adverse neurological and gastrointestinal effects, including jitteriness, irritability, tachycardia, nystagmus, vomiting, diarrhea, and seizures. Star anise products associated with these symptoms are often found to be contaminated with Japanese star anise (Illicium anisatum), which has known toxicity (11384,13058,76290,76293,100159,108932). However, large doses of star anise can also cause neurotoxicity (108932).
PREGNANCY AND LACTATION: LIKELY SAFE
when used orally in amounts commonly found in foods (4912).
PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when star anise is used orally as a tea.
In 2003, the US Food and Drug Administration (FDA) issued an advisory to the public not to consume teas brewed from star anise, as they have been associated with adverse neurological and gastrointestinal effects (11384,13058,76290,76293,100159,108932).
Below is general information about the interactions of the known ingredients contained in the product Illicium Supreme 450 mg. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the adverse effects of the known ingredients contained in the product Illicium Supreme 450 mg. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, star anise is generally well tolerated when consumed in the amounts commonly found in food.
However, star anise tea is associated with serious neurological adverse effects which may or may not be related to contamination with Japanese star anise (Illicium apisatum).
Serious Adverse Effects (Rare):
Orally: Tea made from star anise has been associated with increased deep tendon reflexes, irritability, jitteriness, rapid eye movements, seizures, and vomiting. However, it is unclear if these effects are due to star anise or contamination with Japanese star anise (Illicium apisatum), which is known to be toxic due to its anisatin constituents.
Dermatologic ...Topically, the anethole constituent of star anise can cause dermatitis, including erythema, scaling, and vesiculation (13668,13669).
Gastrointestinal ...Orally, star anise tea has been reported to cause vomiting, diarrhea, and abdominal distension. The teas consumed in these reports may or may not have been contaminated with Japanese star anise (Illicum apisatum) (10407,13058,100159,108932).
Immunologic ...Topically, star anise and the constituents anethole, alpha-pinene, limonene, and safrole can cause allergic reactions in sensitive individuals (13669,76299).
Neurologic/CNS ...Orally, star anise tea has been reported to cause acute onset of irritability, jitteriness, hyperexcitability, clonus or myoclonus, increased deep tendon reflexes, rapid eye movements, nystagmus, and seizures. The teas consumed in these reports may or may not have been contaminated with Japanese star anise (Illicum apisatum) (10407,11384,13058,100159,108932).