Black Rice Extract by BioAnue

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Age-related cognitive decline. It is unclear if oral black rice extract is beneficial for improving memory in older adults. Details: Preliminary clinical research in people 50 years of age and older with subjective reports of memory impairment shows that taking a black rice extract enriched with cyanidin-3-glucoside as 1 gram three times daily for 12 weeks improves subjective memory when compared with placebo (103829). However, the subjects had no impairment in standardized memory tests either before or after the intervention.
• Allergic rhinitis (hay fever). Although there is interest in using oral black rice for allergic rhinitis, there is insufficient reliable information about the clinical effects of black rice for this condition.
• Atopic dermatitis (eczema). Although there is interest in using oral black rice for eczema, there is insufficient reliable information about the clinical effects of black rice for this condition.
• Coronary Heart Disease (CHD). It is unclear if oral black rice pigment is beneficial for improving metabolic parameters in adults with CHD. Details: Clinical research in adults with CHD shows that taking black rice pigment fraction 10 grams daily for 6 months does not affect total cholesterol, triglyceride, low density lipoprotein (LDL) cholesterol, or high-density lipoprotein (HDL) cholesterol levels when compared with white rice pigment fraction (92518).
• Obesity. It is unclear if oral black rice extract is beneficial for weight loss in postmenopausal adults. Details: Preliminary clinical research in postmenopausal adults with obesity shows that taking black rice extract 1000 mg orally daily for 12 weeks does not improve body weight, abdominal fat, subcutaneous fat, or waist circumference when compared with placebo (108667).
• Physical performance. It is unclear if oral black rice improves physical performance in older adults. Details: Preliminary clinical research in healthy adults aged 65-74 years shows that taking black rice germ and bran powder, 5 grams mixed in hot water as a drink twice daily for 24 weeks, in conjunction with an exercise program focused on improving strength and balance, improves gait speed and sit-to-stand time when compared to baseline (103828). However, it is not clear if any improvements are better than exercise alone. No improvement is seen with use of black rice powder alone. More evidence is needed to rate black rice for these uses.

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LIKELY SAFE ...when used orally in amounts commonly found in foods.

POSSIBLY SAFE ...when used orally in medicinal amounts. Black rice extract, 1 gram daily for 12 weeks, has been used with apparent safety (108667). A cyanidin-3-glucoside enriched black rice extract, 3 grams daily for 12 weeks, has also been used with apparent safety (103829). A black rice germ and bran powder, 10 grams daily for 24 weeks, has also been used with apparent safety (103828).

PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid amounts greater than those commonly found in foods.

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General ...No adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted.

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