Ingredients | Amount Per Serving |
---|---|
(herb)
(Melilot)
(1:5)
|
0.13 mL |
Glycerin, Chocolate flavor
Below is general information about the effectiveness of the known ingredients contained in the product Sweet Clover (Melilot) Herb Chocolate Flavor. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Sweet Clover (Melilot) Herb Chocolate Flavor. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when preparations of the flowering branch and leaf are used orally in moderate amounts based on clinical use (1,2,18). ...when sweet clover extract is used at a dose of 100 mg for up to 12 weeks (95172).
POSSIBLY UNSAFE ...when excessive amounts of some preparations are used orally because of the potential for transient liver injury. Some researchers suggest that sweet clover intake should contain no more than coumarin 5 mg daily (18,95166).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Sweet Clover (Melilot) Herb Chocolate Flavor. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Details
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Theoretically, concomitant use of sweet clover with hepatoxic drugs might increase the risk of hepatotoxicity.
Details
Orally, large amounts of sweet clover can cause transient liver injury in susceptible individuals, possibly due to coumarin content (18). In one case report, a patient with multiple sclerosis developed jaundiced palms and a slight elevation in serum alanine aminotransferase (ALT) after taking sweet clover containing coumarin 10 mg daily for 3 years. Two weeks after starting therapy with subcutaneous interferon (IFN)-beta 1b, aspartate transaminase (AST) and ALT levels increased to 7 and 17 times the upper limit of normal, respectively. Levels normalized after discontinuation of both products. Subsequent use of IFN-beta 1a alone, without sweet clover, resulted in only a very slight increase in AST (95166).
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Below is general information about the adverse effects of the known ingredients contained in the product Sweet Clover (Melilot) Herb Chocolate Flavor. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, sweet clover is generally well tolerated when taken in small to moderate amounts.
Topically or intravenously, no adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted for any use.
Serious Adverse Effects (Rare):
Orally: Large amounts have been reported to cause stupor and transient liver injury.
Hematologic ...A case of bleeding diathesis following ingestion of large amounts of a multi-herb, "seasonal tonic" tea made up of the coumarin-containing herbs sweet clover, sweet woodruff, and tonka bean for two months has been reported (809). It is unclear if this event is due to sweet clover, other ingredients, or the combination.
Hepatic ...Orally, large amounts of sweet clover can cause transient liver injury in susceptible individuals (18). A 23-year-old female with multiple sclerosis (MS) developed jaundiced palms and a slight elevation in serum alanine aminotransferase (ALT) without hyperbilirubinemia after taking a sweet clover supplement containing coumarin 10 mg daily (95166).
Neurologic/CNS ...Although rare, headache has been reported with oral use of sweet clover (1,2,18). Large amounts can cause stupor (18).