Ingredients | Amount Per Serving |
---|---|
(4:1)
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1000 mg |
Below is general information about the effectiveness of the known ingredients contained in the product Onion 4:1 Extract Powder. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Onion 4:1 Extract Powder. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when consumed in amounts commonly found in foods. Onion has Generally Recognized as Safe (GRAS) status in the US (4912). ...when onion extract is used topically (66742,66883,66895,66903,67089,95151,95154,95156).
POSSIBLY SAFE ...when onion extract is used orally and appropriately (2). Onion extract has been used safely in doses of 300 mg three times daily for up to 12 weeks (95149,101747).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using in amounts greater than used in foods.
Below is general information about the interactions of the known ingredients contained in the product Onion 4:1 Extract Powder. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, concomitant use of anticoagulant or antiplatelet drugs with onion might increase the risk of bleeding.
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Concomitant use of antidiabetes drugs with onion may increase the risk of hypoglycemia.
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Concomitant use of aspirin with onion may worsen onion allergy.
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In one case report, a patient with a mild onion allergy reported worsening allergy, including swelling and severe urticaria, after taking aspirin (5054).
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Theoretically, taking onion might increase the levels and clinical effects of drugs metabolized by CYP2E1.
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Animal research shows that taking onion powder inhibits CYP2E1 (19653). However, this interaction has not been reported in humans.
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Below is general information about the adverse effects of the known ingredients contained in the product Onion 4:1 Extract Powder. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, onion is well tolerated.
Topically, onion is generally well tolerated.
Most Common Adverse Effects:
Orally: Abdominal pain, heartburn.
Topically: Eczema, irritation.
Serious Adverse Effects (Rare):
All ROAs: Anaphylaxis in sensitive individuals.
Dermatologic ...Topically, frequent contact with onions can result in hand eczema, pemphigus, sensitization, and irritation (18,5004,51303,67066,67093).
Gastrointestinal ...The consumption of large quantities of onions or onion powder can cause stomach distress or heartburn (18,95155,104772). Stomach distress from onion powder appears to be transient (104772). In one case report, consumption of raw onions led to esophageal spasm (66841).
Immunologic ...Allergy to onion is rare, although there are reports of symptoms to both oral and topical exposure (41752,101743). In one case, oral exposure or the aroma of onions caused the sensation of throat closing in an allergic woman (88404). In a 35-year-old man, cooked onion ingestion triggered anaphylaxis (101742). In another case, the smell of onion was identified as a trigger for migraines in a 32-year-old female. Because the patient had a positive allergy skin test for onion, allergenic or immunogenic mechanisms were considered to be the origin of the migraines (88404).
Ocular/Otic ...Exposure to onion aroma can cause excessive tearing (67049).