Ingredients | Not Present |
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(flowers)
((Meets the requirements of the California Organic Foods Act of 1990.) (Certified Biodynamic(R) by the Demeter Association, Inc.))
(infusion of Hound's Tongue PlantPart: flowers Note: (Meets the requirements of the California Organic Foods Act of 1990.) (Certified Biodynamic(R) by the Demeter Association, Inc.) )
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brandy Note: (Meets the requirements of the California Organic Foods Act of 1990.) (Certified Biodynamic(R) by the Demeter Association, Inc.), Water, 40% Alcohol
Below is general information about the effectiveness of the known ingredients contained in the product Hound's Tongue. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of hound's tongue.
Below is general information about the safety of the known ingredients contained in the product Hound's Tongue. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY UNSAFE ...when products containing hepatotoxic pyrrolizidine alkaloid (PA) constituents are used orally. Repeated exposure to low concentrations of hepatotoxic PAs can cause severe veno-occlusive disease. Hepatotoxic PAs might also be carcinogenic and mutagenic (12841,12842). ...when products containing hepatotoxic PAs are used topically on abraded or broken skin. Absorption of hepatotoxic PAs through broken skin can lead to systemic toxicity (12841). There is insufficient reliable information available about the safety of PA-free hound's tongue when used orally or topically.
PREGNANCY: LIKELY UNSAFE
when used orally.
Hound's tongue preparations containing pyrrolizidine alkaloid (PA) constituents might be teratogenic and hepatotoxic (12841,12842). There is insufficient reliable information available about the safety of using PA-free hound's tongue products during pregnancy.
LACTATION: LIKELY UNSAFE
when used orally.
Hepatotoxic pyrrolizidine alkaloid (PA) constituents in hound's tongue are excreted in milk (12841,12842). There is insufficient reliable information available about the safety of using PA-free hound's tongue products during lactation.
Below is general information about the interactions of the known ingredients contained in the product Hound's Tongue. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, CYP3A4 inducers can increase the toxicity of the pyrrolizidine alkaloid (PA) constituents of hound's tongue.
Details
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Below is general information about the adverse effects of the known ingredients contained in the product Hound's Tongue. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, all parts of the plant are considered toxic due to the presence of pyrrolizidine alkaloids (PAs), which can be hepatotoxic, pneumotoxic, carcinogenic, and mutagenic.
Hepatic ...The pyrrolizidine alkaloid (PA) constituents of hound's tongue are hepatotoxic (12841,12842). Chronic exposure to other plants containing hepatotoxic PA constituents is associated with veno-occlusive disease (VOD) (4021). Subacute VOD causes vague symptoms with persistent liver enlargement (4021). Symptoms of acute VOD include epigastric pain, vomiting and diarrhea, and ascites formation within several days. Enlargement and induration of the liver occurs within a few weeks (12842).
Oncologic ...The pyrrolizidine alkaloid (PA) constituents of hound's tongue are considered carcinogenic and mutagenic (12841,12842).
Pulmonary/Respiratory ...The pyrrolizidine alkaloid (PA) constituents of hound's tongue are considered pneumotoxic (12841,12842).