Ingredients | Not Present |
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A Proprietary Blend
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(Taxus brevifolia )
(Beeswax)
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Below is general information about the effectiveness of the known ingredients contained in the product Yew Salve. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
There is insufficient reliable information available about the effectiveness of yew.
Below is general information about the safety of the known ingredients contained in the product Yew Salve. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Beeswax has Generally Recognized as Safe (GRAS) status in the US (4912). ...when used orally as a medicinal agent (11)....when used topically (11,55245,96328,96329).
PREGNANCY AND LACTATION:
There is insufficient reliable information available about the safety of medicinal amounts of beeswax during pregnancy and lactation.
LIKELY UNSAFE ...when used orally (6,18). All parts of the yew plant are considered poisonous (5604). Ingestion of 50-100 grams, or 0.6-1.3 grams/kg, of yew needles can cause death (18,5604,105514,105515). Yew can cause severe gastrointestinal irritation and can cause the heart to beat dangerously slow, fast, or irregularly (17,159,5604,86746,86756,100036,100037,100038,100039,100040,105514,105515). Many of the reported fatalities have occurred after ingestion of large amounts of plant material, especially yew needles (5603,5604,5605,86755,86756,86758,86763,100037,100041,105514,105515).
CHILDREN: UNSAFE
when the berries or needles are used orally.
One chewed berry is potentially lethal (159). Ingesting the berries or needles can cause the heart to beat dangerously slow or fast (86753,86760).
PREGNANCY AND LACTATION: UNSAFE
when the needles are used orally.
Yew needles have been used as an abortifacient (16,18).
Below is general information about the interactions of the known ingredients contained in the product Yew Salve. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the adverse effects of the known ingredients contained in the product Yew Salve. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, beeswax is well tolerated.
Allergic reactions to beeswax are possible in some patients (11).
Topically, beeswax may cause allergic contact dermatitis. In most cases, this reaction is likely caused by the propolis component of beeswax (55245,102517).
Dermatologic ...Topically, beeswax may cause allergic contact dermatitis. In most cases, this reaction is likely caused by the propolis component of beeswax (55245,102517). While this reaction is thought to be rare in the general population, one cross-sectional study found that 18% of patients with a history of cheilitis or facial dermatitis experienced positive reactions to beeswax. While most of these patients also had a positive reaction to a propolis patch test, some did not, suggesting that a substance in beeswax itself may be involved in this sensitization (102517).
Immunologic ...Orally, beeswax may cause allergic reactions (11). Topically, beeswax may cause allergic contact dermatitis. In most cases, this reaction is likely caused by the propolis component of beeswax (102517).
General ...Orally, symptoms of yew poisoning include queasiness, dry mouth, (18) vomiting, vertigo, severe abdominal pain, weakness (5604,5605,100036,100037,100038,100039,100040,105514,105515), nervousness, trembling, dyspnea, incoordination (5603), tachycardia, bradycardia, arrhythmias, ventricular fibrillation, hypotension, unconsciousness, coma (5604,86746,86756,100036,100038,100039,100040,105514,105515), dizziness, seizures (100038,105514), respiratory depression (100037), mydriasis, reddening of the lips, pale and cyanotic skin (6,18,5605), and death secondary to cardiac arrest (5604,105514,105515). Usually, gastrointestinal and neurological symptoms occur early, within 30-90 minutes, followed by cardiovascular symptoms and death within 24 hours (100038,105515). Some people are allergic to yew following airborne exposure (86745,100014).
Cardiovascular
...Orally, symptoms of yew poisoning include tachycardia, bradycardia, arrhythmias, hypotension, ventricular fibrillation, and death due to cardiac arrest (5604,86746,86756,100036,100038,100039,100040,105514,105515).
Usually, gastrointestinal and neurological symptoms occur early, within 30-90 minutes, followed by cardiovascular symptoms and death within 24 hours (100038,105514,105515).
Treatment is usually related to supportive care, however, arrhythmias are often resistant to standard pharmacologic treatments and transvenous or external pacemakers (100040,105514,105515). Lipid emulsion therapy and digoxin-binding antibodies have also been used to treat yew poisoning, but the effects are unclear (105514). Veno-arterial extracorporeal membrane oxygenation (VA ECMO) has been used as a bridge during taxine elimination and cardiac recovery (100039,100040,105514). VA ECMO has typically been used for 72 hours or less (105514).
Dermatologic ...Orally, symptoms of yew poisoning include reddening of the lips and pale and cyanotic skin (6,18,5605).
Gastrointestinal ...Orally, initial symptoms of yew poisoning include queasiness, dry mouth, (18) nausea, vomiting, and severe abdominal pain (5604,5605,100036,100037,100038,100039,100040,105514,105515). Usually, gastrointestinal and neurological symptoms occur early, within 30-90 minutes, followed by cardiovascular symptoms and death within 24 hours (100038,105515).
Immunologic ...There is at least one known case of a patient with yew allergy associated with airborne exposure to yew trees (100014). Based on this case report, it was also determined that people who are allergic to yew might become hypersensitive to docetaxel, which is derived from yew (100014). Pollen from yew has caused nasal allergy in 18 patients (86745).
Neurologic/CNS ...Orally, symptoms of yew poisoning include vertigo, weakness (5604), nervousness, trembling, loss of coordination (5603), unconsciousness, coma (5604,100036,105515), dizziness, seizures (100038,105514), respiratory depression (100037), and mydriasis (6,18). Usually, gastrointestinal and neurological symptoms occur early, within 30-90 minutes, followed by cardiovascular symptoms and death within 24 hours (100038,105515).
Pulmonary/Respiratory ...Orally, symptoms of yew poisoning include dyspnea (5603).