Each capsule contains: 4-Androstenediol 250 mg.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
This product has been discontinued by the manufacturer. This product contains androstenediol. In January 2005 legislation went into effect in the United States called the Anabolic Steroid Control Act of 2004. This reclassifies androstenediol from a dietary supplement to an anabolic steroid, which is a schedule III controlled substance (8639).
Below is general information about the effectiveness of the known ingredients contained in the product 4-Diol 250. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the safety of the known ingredients contained in the product 4-Diol 250. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY UNSAFE ...when used orally; the potency and purity of androstenediol products can differ significantly from the product label (10641).
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product 4-Diol 250. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Androstenediol is a precursor to estrogen and can increase levels of estradiol and estrone (1905,10162). There is some concern that taking androstenediol with estrogens might increase estrogenic effects and potential side effects. However, androstenediol is converted to estrogen in low estrogen environments. Patients who are taking supplemental estrogen do not have low estrogen levels. Therefore, androstenediol might not be converted to estrogen in these patients. It is unclear how this might alter the effects and side effects of androstenediol. Until more is known, use with caution or avoid using with estrogen-containing drugs. Some of these drugs include CombiPatch, Estraderm Transdermal, Kestrone, Vivelle Transdermal, and others.
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Androstenediol is a precursor to testosterone and can increase levels of testosterone (1905,10162). There is some concern that taking androstenediol with testosterone might increase therapeutic and adverse effects of testosterone. However, androstenediol is converted to testosterone in low testosterone environments. Patients taking supplemental testosterone do not have low testosterone levels. Therefore, androstenediol might not be converted to testosterone in these patients. It is unclear how this might alter the effects and side effects of androstenediol. Until more is known, use with caution or avoid using with testosterone-containing drugs. Some of these drugs include Androderm Transdermal, AndroGel, Depo-Testosterone, Testex, Testoderm, and others.
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Below is general information about the adverse effects of the known ingredients contained in the product 4-Diol 250. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, androstenediol can increase endogenous testosterone production and increase levels of estrone and estradiol (1905,10162). It might weaken tendons and increase the risk of tendon rupture (31255). Theoretically, androstenediol may cause masculinization and increased growth of facial hair in women.
Endocrine ...Orally, androstenediol can increase endogenous testosterone production and increase levels of estrone and estradiol (1905,10162). Theoretically, androstenediol may cause masculinization and increased growth of facial hair in women.
Musculoskeletal ...Orally, bilateral Achilles tendon ruptures have been reported in a 35-year-old male patient. Each rupture occurred following the use androstenediol 100 mg orally daily for one month, with approximately 18 months between each use (31255).
