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Schmidt, M. C., Askew, E. W., Roberts, D. E., Prior, R. L., Ensign, W. Y., Jr., and Hesslink, R. E., Jr. Oxidative stress in humans training in a cold, moderate altitude environment and their response to a phytochemical antioxidant supplement. Wilderness.Environ.Med. 2002;13(2):94-105. View abstract.

Greul, A. K., Grundmann, J. U., Heinrich, F., Pfitzner, I., Bernhardt, J., Ambach, A., Biesalski, H. K., and Gollnick, H. Photoprotection of UV-irradiated human skin: an antioxidative combination of vitamins E and C, carotenoids, selenium and proanthocyanidins. Skin Pharmacol Appl.Skin Physiol 2002;15(5):307-315. View abstract.

Prince, M. I., Mitchison, H. C., Ashley, D., Burke, D. A., Edwards, N., Bramble, M. G., James, O. F., and Jones, D. E. Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis: results of a multicentre, randomized, placebo-controlled, cross-over trial. Aliment.Pharmacol.Ther. 2003;17(1):137-143. View abstract.

Wood, L. G., Fitzgerald, D. A., Lee, A. K., and Garg, M. L. Improved antioxidant and fatty acid status of patients with cystic fibrosis after antioxidant supplementation is linked to improved lung function. Am.J.Clin.Nutr. 2003;77(1):150-159. View abstract.

Bjelakovic, G., Nikolova, D., Simonetti, R. G., and Gluud, C. Antioxidant supplements for preventing gastrointestinal cancers. Cochrane.Database.Syst.Rev. 2004;(4):CD004183. View abstract.

McNaughton, S. A., Marks, G. C., and Green, A. C. Role of dietary factors in the development of basal cell cancer and squamous cell cancer of the skin. Cancer Epidemiol.Biomarkers Prev. 2005;14(7):1596-1607. View abstract.

Coulter, I. D., Hardy, M. L., Morton, S. C., Hilton, L. G., Tu, W., Valentine, D., and Shekelle, P. G. Antioxidants vitamin C and vitamin e for the prevention and treatment of cancer. J Gen.Intern Med 2006;21(7):735-744. View abstract.

Bjelakovic, G., Nagorni, A., Nikolova, D., Simonetti, R. G., Bjelakovic, M., and Gluud, C. Meta-analysis: antioxidant supplements for primary and secondary prevention of colorectal adenoma. Aliment.Pharmacol Ther 7-15-2006;24(2):281-291. View abstract.

Huang, H. Y., Caballero, B., Chang, S., Alberg, A. J., Semba, R. D., Schneyer, C. R., Wilson, R. F., Cheng, T. Y., Vassy, J., Prokopowicz, G., Barnes, G. J., and Bass, E. B. The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the-science conference. Ann.Intern.Med. 9-5-2006;145(5):372-385. View abstract.

Kamangar, F., Qiao, Y. L., Yu, B., Sun, X. D., Abnet, C. C., Fan, J. H., Mark, S. D., Zhao, P., Dawsey, S. M., and Taylor, P. R. Lung cancer chemoprevention: a randomized, double-blind trial in Linxian, China. Cancer Epidemiol.Biomarkers Prev. 2006;15(8):1562-1564. View abstract.

Bleys, J., Miller, E. R., III, Pastor-Barriuso, R., Appel, L. J., and Guallar, E. Vitamin-mineral supplementation and the progression of atherosclerosis: a meta-analysis of randomized controlled trials. Am.J Clin.Nutr 2006;84(4):880-887. View abstract.

Hercberg, S., Ezzedine, K., Guinot, C., Preziosi, P., Galan, P., Bertrais, S., Estaquio, C., Briancon, S., Favier, A., Latreille, J., and Malvy, D. Antioxidant supplementation increases the risk of skin cancers in women but not in men. J.Nutr. 2007;137(9):2098-2105. View abstract.

Bardia, A., Tleyjeh, I. M., Cerhan, J. R., Sood, A. K., Limburg, P. J., Erwin, P. J., and Montori, V. M. Efficacy of antioxidant supplementation in reducing primary cancer incidence and mortality: systematic review and meta-analysis. Mayo Clin.Proc. 2008;83(1):23-34. View abstract.

Evans, J. R. and Henshaw, K. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. Cochrane.Database.Syst.Rev. 2008;(1):CD000253. View abstract.

Bjelakovic, G., Nikolova, D., Gluud, L. L., Simonetti, R. G., and Gluud, C. Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane.Database.Syst.Rev. 2008;(2):CD007176. View abstract.

Bjelakovic, G., Nikolova, D., Simonetti, R. G., and Gluud, C. Antioxidant supplements for preventing gastrointestinal cancers. Cochrane.Database.Syst.Rev. 2008;(3):CD004183. View abstract.

Wenzel, G., Kuklinski, B., Ruhlmann, C., and Ehrhardt, D. [Alcohol-induced toxic hepatitis--a "free radical" associated disease. Lowering fatality by adjuvant antioxidant therapy]. Z.Gesamte Inn.Med. 1993;48(10):490-496. View abstract.

Hofstad, B., Almendingen, K., Vatn, M., Andersen, S. N., Owen, R. W., Larsen, S., and Osnes, M. Growth and recurrence of colorectal polyps: a double-blind 3-year intervention with calcium and antioxidants. Digestion 1998;59(2):148-156. View abstract.

Witte, K. K., Nikitin, N. P., Parker, A. C., von Haehling, S., Volk, H. D., Anker, S. D., Clark, A. L., and Cleland, J. G. The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure. Eur Heart J 2005;26(21):2238-2244. View abstract.

Pepe, S., Leong, J. Y., Van der Merwe, J., Marasco, S. F., Hadj, A., Lymbury, R., Perkins, A., and Rosenfeldt, F. L. Targeting oxidative stress in surgery: effects of ageing and therapy. Exp.Gerontol. 2008;43(7):653-657. View abstract.

Lockwood, K., Moesgaard, S., Hanioka, T., and Folkers, K. Apparent partial remission of breast cancer in 'high risk' patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol.Aspects Med 1994;15 Suppl:s231-s240. View abstract.

Kubik, P., Kowalska, B., Laskowska-Klita, T., Chelchowska, M., and Leibschang, J. [Effect of vitamin-mineral supplementation on the status of some microelements in pregnant women]. Przegl.Lek. 2004;61(7):764-768. View abstract.

Li, H., Li, H. Q., Wang, Y., Xu, H. X., Fan, W. T., Wang, M. L., Sun, P. H., and Xie, X. Y. An intervention study to prevent gastric cancer by micro-selenium and large dose of allitridum. Chin Med.J.(Engl.) 2004;117(8):1155-1160. View abstract.

Zhang, L., Gail, M. H., Wang, Y. Q., Brown, L. M., Pan, K. F., Ma, J. L., Amagase, H., You, W. C., and Moslehi, R. A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins. Am.J.Clin.Nutr. 2006;84(4):912-919. View abstract.

Dunstan, J. A., Breckler, L., Hale, J., Lehmann, H., Franklin, P., Lyons, G., Ching, S. Y., Mori, T. A., Barden, A., and Prescott, S. L. Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial. Clin Exp.Allergy 2007;37(2):180-187. View abstract.

Ma, J. L., Zhang, L., Brown, L. M., Li, J. Y., Shen, L., Pan, K. F., Liu, W. D., Hu, Y., Han, Z. X., Crystal-Mansour, S., Pee, D., Blot, W. J., Fraumeni, J. F., Jr., You, W. C., and Gail, M. H. Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality. J.Natl.Cancer Inst. 3-21-2012;104(6):488-492. View abstract.

Moreno-Reyes, R., Mathieu, F., Boelaert, M., Begaux, F., Suetens, C., Rivera, M. T., Neve, J., Perlmutter, N., and Vanderpas, J. Selenium and iodine supplementation of rural Tibetan children affected by Kashin-Beck osteoarthropathy. Am J Clin Nutr 2003;78(1):137-144. View abstract.

Block, K. I., Koch, A. C., Mead, M. N., Tothy, P. K., Newman, R. A., and Gyllenhaal, C. Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. Int.J Cancer 9-15-2008;123(6):1227-1239. View abstract.

Rumiris, D., Purwosunu, Y., Wibowo, N., Farina, A., and Sekizawa, A. Lower rate of preeclampsia after antioxidant supplementation in pregnant women with low antioxidant status. Hypertens.Pregnancy. 2006;25(3):241-253. View abstract.

Safarinejad, M. R. and Safarinejad, S. Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study. J Urol. 2009;181(2):741-751. View abstract.

Olsen, A., Thiong'o, F. W., Ouma, J. H., Mwaniki, D., Magnussen, P., Michaelsen, K. F., Friis, H., and Geissler, P. W. Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren. Trans.R.Soc.Trop.Med.Hyg. 2003;97(1):109-114. View abstract.

Ciliberto, H., Ciliberto, M., Briend, A., Ashorn, P., Bier, D., and Manary, M. Antioxidant supplementation for the prevention of kwashiorkor in Malawian children: randomised, double blind, placebo controlled trial. BMJ 5-14-2005;330(7500):1109. View abstract.

Pfeiffer, J. M., Askew, E. W., Roberts, D. E., Wood, S. M., Benson, J. E., Johnson, S. C., and Freedman, M. S. Effect of antioxidant supplementation on urine and blood markers of oxidative stress during extended moderate-altitude training. Wilderness.Environ.Med 1999;10(2):66-74. View abstract.

Chao, W. H., Askew, E. W., Roberts, D. E., Wood, S. M., and Perkins, J. B. Oxidative stress in humans during work at moderate altitude. J Nutr. 1999;129(11):2009-2012. View abstract.

Schumacher, K. [Effect of selenium on the side effect profile of adjuvant chemotherapy/radiotherapy in patients with breast carcinoma. Design for a clinical study]. Med Klin.(Munich) 10-15-1999;94 Suppl 3:45-48. View abstract.

Welch, R. W., Turley, E., Sweetman, S. F., Kennedy, G., Collins, A. R., Dunne, A., Livingstone, M. B., McKenna, P. G., McKelvey-Martin, V. J., and Strain, J. J. Dietary antioxidant supplementation and DNA damage in smokers and nonsmokers. Nutr.Cancer 1999;34(2):167-172. View abstract.

Temple, K. A., Smith, A. M., and Cockram, D. B. Selenate-supplemented nutritional formula increases plasma selenium in hemodialysis patients. J Ren Nutr. 2000;10(1):16-23. View abstract.

Darlow, B. A., Winterbourn, C. C., Inder, T. E., Graham, P. J., Harding, J. E., Weston, P. J., Austin, N. C., Elder, D. E., Mogridge, N., Buss, I. H., and Sluis, K. B. The effect of selenium supplementation on outcome in very low birth weight infants: a randomized controlled trial. The New Zealand Neonatal Study Group. J Pediatr 2000;136(4):473-480. View abstract.

Winterbourn, C. C., Chan, T., Buss, I. H., Inder, T. E., Mogridge, N., and Darlow, B. A. Protein carbonyls and lipid peroxidation products as oxidation markers in preterm infant plasma: associations with chronic lung disease and retinopathy and effects of selenium supplementation. Pediatr.Res. 2000;48(1):84-90. View abstract.

Seppanen, K., Kantola, M., Laatikainen, R., Nyyssonen, K., Valkonen, V. P., Kaarlopp, V., and Salonen, J. T. Effect of supplementation with organic selenium on mercury status as measured by mercury in pubic hair. J Trace Elem.Med Biol. 2000;14(2):84-87. View abstract.

Miller, A. L. The etiologies, pathophysiology, and alternative/complementary treatment of asthma. Altern.Med Rev. 2001;6(1):20-47. View abstract.

Federico, A., Iodice, P., Federico, P., Del Rio, A., Mellone, M. C., Catalano, G., and Federico, P. Effects of selenium and zinc supplementation on nutritional status in patients with cancer of digestive tract. Eur J Clin Nutr 2001;55(4):293-297. View abstract.

Kalita, B., Nowak, P., Slimok, M., Sikora, A., Szkilnik, R., Obuchowicz, A., Sulej, J., and Sabat, D. [Selenium plasma concentration level in children with food allergy]. Pol.Merkur Lekarski. 2001;10(60):411-413. View abstract.

Kiremidjian-Schumacher, L. and Roy, M. Effect of selenium on the immunocompetence of patients with head and neck cancer and on adoptive immunotherapy of early and established lesions. Biofactors 2001;14(1-4):161-168. View abstract.

Elsendoorn, T. J., Weijl, N. I., Mithoe, S., Zwinderman, A. H., Van, Dam F., De Zwart, F. A., Tates, A. D., and Osanto, S. Chemotherapy-induced chromosomal damage in peripheral blood lymphocytes of cancer patients supplemented with antioxidants or placebo. Mutat.Res. 11-15-2001;498(1-2):145-158. View abstract.

Ogawa, A., Ogawa, I., Obayashi, R., Umezu, K., Doi, M., and Hirao, T. Highly Selective Thioselenation of Vinylcyclopropanes with a (PhS)(2)-(PhSe)(2) Binary System and Its Application to Thiotelluration. J Org.Chem. 1-8-1999;64(1):86-92. View abstract.

Adamowicz, A., Trafikowska, U., Trafikowska, A., Zachara, B., and Manitius, J. Effect of erythropoietin therapy and selenium supplementation on selected antioxidant parameters in blood of uremic patients on long- term hemodialysis. Med Sci Monit. 2002;8(3):CR202-CR205. View abstract.

Vinceti, M., Wei, E. T., Malagoli, C., Bergomi, M., and Vivoli, G. Adverse health effects of selenium in humans. Rev.Environ.Health 2001;16(4):233-251. View abstract.

Gazdik, F., Kadrabova, J., and Gazdikova, K. Decreased consumption of corticosteroids after selenium supplementation in corticoid-dependent asthmatics. Bratisl.Lek.Listy 2002;103(1):22-25. View abstract.

Apostolidis, N. S., Panoussopoulos, D. G., Stamou, K. M., Kekis, P. B., Paradellis, T. P., Karydas, A. G., Zarkadas, C., Zirogiannis, P. N., and Manouras, A. J. Selenium metabolism in patients on continuous ambulatory peritoneal dialysis. Perit.Dial.Int 2002;22(3):400-404. View abstract.

Bialy, T. L., Rothe, M. J., and Grant-Kels, J. M. Dietary factors in the prevention and treatment of nonmelanoma skin cancer and melanoma. Dermatol.Surg. 2002;28(12):1143-1152. View abstract.

Burbano, X., Miguez-Burbano, M. J., McCollister, K., Zhang, G., Rodriguez, A., Ruiz, P., Lecusay, R., and Shor-Posner, G. Impact of a selenium chemoprevention clinical trial on hospital admissions of HIV-infected participants. HIV.Clin.Trials 2002;3(6):483-491. View abstract.

Benton, D. Selenium intake, mood and other aspects of psychological functioning. Nutr.Neurosci. 2002;5(6):363-374. View abstract.

Kelley, M. J. and McCrory, D. C. Prevention of lung cancer: summary of published evidence. Chest 2003;123(1 Suppl):50S-59S. View abstract.

Keskes-Ammar, L., Feki-Chakroun, N., Rebai, T., Sahnoun, Z., Ghozzi, H., Hammami, S., Zghal, K., Fki, H., Damak, J., and Bahloul, A. Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men. Arch.Androl 2003;49(2):83-94. View abstract.

Margaritis, I., Palazzetti, S., Rousseau, A. S., Richard, M. J., and Favier, A. Antioxidant supplementation and tapering exercise improve exercise-induced antioxidant response. J Am.Coll.Nutr. 2003;22(2):147-156. View abstract.

Bertolini, G., Iapichino, G., Radrizzani, D., Facchini, R., Simini, B., Bruzzone, P., Zanforlin, G., and Tognoni, G. Early enteral immunonutrition in patients with severe sepsis: results of an interim analysis of a randomized multicentre clinical trial. Intensive Care Med. 2003;29(5):834-840. View abstract.

Wallace, K., Byers, T., Morris, J. S., Cole, B. F., Greenberg, E. R., Baron, J. A., Gudino, A., Spate, V., and Karagas, M. R. Prediagnostic serum selenium concentration and the risk of recurrent colorectal adenoma: a nested case-control study. Cancer Epidemiol.Biomarkers Prev. 2003;12(5):464-467. View abstract.

Shor-Posner, G., Lecusay, R., Miguez, M. J., Moreno-Black, G., Zhang, G., Rodriguez, N., Burbano, X., Baum, M., and Wilkie, F. Psychological burden in the era of HAART: impact of selenium therapy. Int J Psychiatry Med 2003;33(1):55-69. View abstract.

Singhal, N. and Austin, J. A clinical review of micronutrients in HIV infection. J Int Assoc.Physicians AIDS Care (Chic.) 2002;1(2):63-75. View abstract.

Abrams, C. K., Siram, S. M., Galsim, C., Johnson-Hamilton, H., Munford, F. L., and Mezghebe, H. Selenium deficiency in long-term total parenteral nutrition. Nutr Clin Pract 1992;7(4):175-178. View abstract.

Li, W. G. [Preliminary observations on effect of selenium yeast on high risk populations with primary liver cancer]. Zhonghua Yu Fang Yi.Xue.Za Zhi. 1992;26(5):268-271. View abstract.

Serwin, A. B., Mysliwiec, H., Hukalowicz, K., Porebski, P., Borawska, M., and Chodynicka, B. Soluble tumor necrosis factor-alpha receptor type 1 during selenium supplementation in psoriasis patients. Nutrition 2003;19(10):847-850. View abstract.

Darlow, B. A. and Austin, N. C. Selenium supplementation to prevent short-term morbidity in preterm neonates. Cochrane.Database.Syst.Rev. 2003;(4):CD003312. View abstract.

Schrauzer, G. N. The nutritional significance, metabolism and toxicology of selenomethionine. Adv.Food Nutr.Res. 2003;47:73-112. View abstract.

Allsup, S. J., Shenkin, A., Gosney, M. A., Taylor, S., Taylor, W., Hammond, M., and Zambon, M. C. Can a short period of micronutrient supplementation in older institutionalized people improve response to influenza vaccine? A randomized, controlled trial. J Am.Geriatr.Soc. 2004;52(1):20-24. View abstract.

Al-Taie, O. H., Seufert, J., Karvar, S., Adolph, C., Mork, H., Scheurlen, M., Kohrle, J., and Jakob, F. Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and present carriers of colon adenomas. Nutr.Cancer 2003;46(2):125-130. View abstract.

Allam, M. F. and Lucane, R. A. Selenium supplementation for asthma. Cochrane.Database.Syst.Rev. 2004;(2):CD003538. View abstract.

Broome, C. S., McArdle, F., Kyle, J. A., Andrews, F., Lowe, N. M., Hart, C. A., Arthur, J. R., and Jackson, M. J. An increase in selenium intake improves immune function and poliovirus handling in adults with marginal selenium status. Am.J.Clin.Nutr. 2004;80(1):154-162. View abstract.

Angstwurm, M. W., Schopohl, J., and Gaertner, R. Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients. Eur.J Endocrinol. 2004;151(1):47-54. View abstract.

Weijl, N. I., Elsendoorn, T. J., Lentjes, E. G., Hopman, G. D., Wipkink-Bakker, A., Zwinderman, A. H., Cleton, F. J., and Osanto, S. Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: a randomised, double-blind, placebo-controlled study. Eur.J Cancer 2004;40(11):1713-1723. View abstract.

Pan, S. Y., Ugnat, A. M., Mao, Y., Wen, S. W., and Johnson, K. C. A case-control study of diet and the risk of ovarian cancer. Cancer Epidemiol.Biomarkers Prev. 2004;13(9):1521-1527. View abstract.

Reid, M. E., Stratton, M. S., Lillico, A. J., Fakih, M., Natarajan, R., Clark, L. C., and Marshall, J. R. A report of high-dose selenium supplementation: response and toxicities. J Trace Elem.Med Biol. 2004;18(1):69-74. View abstract.

Subudhi, A. W., Jacobs, K. A., Hagobian, T. A., Fattor, J. A., Fulco, C. S., Muza, S. R., Rock, P. B., Hoffman, A. R., Cymerman, A., and Friedlander, A. L. Antioxidant supplementation does not attenuate oxidative stress at high altitude. Aviat.Space Environ.Med 2004;75(10):881-888. View abstract.

Rayman, M. P. The use of high-selenium yeast to raise selenium status: how does it measure up? Br.J Nutr. 2004;92(4):557-573. View abstract.

Smolkova, B., Dusinska, M., Raslova, K., Barancokova, M., Kazimirova, A., Horska, A., Spustova, V., and Collins, A. Folate levels determine effect of antioxidant supplementation on micronuclei in subjects with cardiovascular risk. Mutagenesis 2004;19(6):469-476. View abstract.

Peretz, A., Neve, J., Duchateau, J., and Famaey, J. P. Adjuvant treatment of recent onset rheumatoid arthritis by selenium supplementation: preliminary observations. Br.J Rheumatol. 1992;31(4):281-282. View abstract.

McClelland, R. S., Baeten, J. M., Overbaugh, J., Richardson, B. A., Mandaliya, K., Emery, S., Lavreys, L., Ndinya-Achola, J. O., Bankson, D. D., Bwayo, J. J., and Kreiss, J. K. Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial. J Acquir.Immune.Defic.Syndr. 12-15-2004;37(5):1657-1663. View abstract.

Lindner, D., Lindner, J., Baumann, G., Dawczynski, H., and Bauch, K. [Investigation of antioxidant therapy with sodium selenite in acute pancreatitis. A prospective randomized blind trial]. Med Klin.(Munich) 12-15-2004;99(12):708-712. View abstract.

Bonnefont-Rousselot, D. The role of antioxidant micronutrients in the prevention of diabetic complications. Treat.Endocrinol 2004;3(1):41-52. View abstract.

Chelchowska, M., Laskowska-Klita, T., Kubik, P., and Leibschang, J. [The effect of vitamin-mineral supplementation on the level of MDA and activity of glutathione peroxidase and superoxide dismutase in blood of matched maternal-cord pairs]. Przegl.Lek. 2004;61(7):760-763. View abstract.

Mego, M., Ebringer, L., Drgona, L., Mardiak, J., Trupl, J., Greksak, R., Nemova, I., Oravcova, E., Zajac, V., and Koza, I. Prevention of febrile neutropenia in cancer patients by probiotic strain Enterococcus faecium M-74. Pilot study phase I. Neoplasma 2005;52(2):159-164. View abstract.

Xia, Y., Hill, K. E., Byrne, D. W., Xu, J., and Burk, R. F. Effectiveness of selenium supplements in a low-selenium area of China. Am.J.Clin.Nutr. 2005;81(4):829-834. View abstract.

Meltzer, H. M., Norheim, G., Loken, E. B., and Holm, H. Supplementation with wheat selenium induces a dose-dependent response in serum and urine of a Se-replete population. Br.J Nutr. 1992;67(2):287-294. View abstract.

Kim, J., Sun, P., Lam, Y. W., Troncoso, P., Sabichi, A. L., Babaian, R. J., Pisters, L. L., Pettaway, C. A., Wood, C. G., Lippman, S. M., McDonnell, T. J., Lieberman, R., Logothetis, C., and Ho, S. M. Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer. Cancer Epidemiol.Biomarkers Prev. 2005;14(7):1697-1702. View abstract.

Riccioni, G. and D'Orazio, N. The role of selenium, zinc and antioxidant vitamin supplementation in the treatment of bronchial asthma: adjuvant therapy or not? Expert.Opin Investig.Drugs 2005;14(9):1145-1155. View abstract.

Mego, M., Koncekova, R., Mikuskova, E., Drgona, L., Ebringer, L., Demitrovicova, L., Nemova, I., Trupl, J., Mardiak, J., Koza, I., and Zajac, V. Prevention of febrile neutropenia in cancer patients by probiotic strain Enterococcus faecium M-74. Phase II study. Support.Care Cancer 2006;14(3):285-290. View abstract.

Rayman, M., Thompson, A., Warren-Perry, M., Galassini, R., Catterick, J., Hall, E., Lawrence, D., and Bliss, J. Impact of selenium on mood and quality of life: a randomized, controlled trial. Biol Psychiatry 1-15-2006;59(2):147-154. View abstract.

Frank, J. E. Diagnosis and management of G6PD deficiency. Am.Fam.Physician 10-1-2005;72(7):1277-1282. View abstract.

Kuklinski, B., Buchner, M., Schweder, R., and Nagel, R. [Acute pancreatitis--a free radical disease. Decrease in fatality with sodium selenite (Na2SeO3) therapy]. Z.Gesamte Inn.Med 1991;46(5):145-149. View abstract.

Stranges, S., Marshall, J. R., Trevisan, M., Natarajan, R., Donahue, R. P., Combs, G. F., Farinaro, E., Clark, L. C., and Reid, M. E. Effects of selenium supplementation on cardiovascular disease incidence and mortality: secondary analyses in a randomized clinical trial. Am J Epidemiol. 4-15-2006;163(8):694-699. View abstract.

Burk, R. F., Norsworthy, B. K., Hill, K. E., Motley, A. K., and Byrne, D. W. Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial. Cancer Epidemiol.Biomarkers Prev. 2006;15(4):804-810. View abstract.

Serwin, A. B., Wasowicz, W., and Chodynicka, B. Selenium supplementation, soluble tumor necrosis factor-alpha receptor type 1, and C-reactive protein during psoriasis therapy with narrowband ultraviolet B. Nutrition 2006;22(9):860-864. View abstract.

Elango, N., Samuel, S., and Chinnakkannu, P. Enzymatic and non-enzymatic antioxidant status in stage (III) human oral squamous cell carcinoma and treated with radical radio therapy: influence of selenium supplementation. Clin Chim Acta 2006;373(1-2):92-98. View abstract.

Spiller, H. A. and Pfiefer, E. Two fatal cases of selenium toxicity. Forensic Sci Int 8-24-2007;171(1):67-72. View abstract.

Groenbaek, K., Friis, H., Hansen, M., Ring-Larsen, H., and Krarup, H. B. The effect of antioxidant supplementation on hepatitis C viral load, transaminases and oxidative status: a randomized trial among chronic hepatitis C virus-infected patients. Eur J Gastroenterol Hepatol 2006;18(9):985-989. View abstract.

Czernichow, S., Couthouis, A., Bertrais, S., Vergnaud, A. C., Dauchet, L., Galan, P., and Hercberg, S. Antioxidant supplementation does not affect fasting plasma glucose in the Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) study in France: association with dietary intake and plasma concentrations. Am J Clin Nutr 2006;84(2):395-399. View abstract.

Richelle, M., Sabatier, M., Steiling, H., and Williamson, G. Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and selenium. Br J Nutr 2006;96(2):227-238. View abstract.

Berger, M. M., Eggimann, P., Heyland, D. K., Chiolero, R. L., Revelly, J. P., Day, A., Raffoul, W., and Shenkin, A. Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials. Crit Care 2006;10(6):R153. View abstract.

Angstwurm, M. W., Engelmann, L., Zimmermann, T., Lehmann, C., Spes, C. H., Abel, P., Strauss, R., Meier-Hellmann, A., Insel, R., Radke, J., Schuttler, J., and Gartner, R. Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med 2007;35(1):118-126. View abstract.

Mishra, V., Baines, M., Perry, S. E., McLaughlin, P. J., Carson, J., Wenstone, R., and Shenkin, A. Effect of selenium supplementation on biochemical markers and outcome in critically ill patients. Clin Nutr 2007;26(1):41-50. View abstract.

Shaheen, S. O., Newson, R. B., Rayman, M. P., Wong, A. P., Tumilty, M. K., Phillips, J. M., Potts, J. F., Kelly, F. J., White, P. T., and Burney, P. G. Randomised, double blind, placebo-controlled trial of selenium supplementation in adult asthma. Thorax 2007;62(6):483-490. View abstract.

Singh, U., Otvos, J., Dasgupta, A., de Lemos, J. A., Devaraj, S., and Jialal, I. High-dose alpha-tocopherol therapy does not affect HDL subfractions in patients with coronary artery disease on statin therapy. Clin Chem 2007;53(3):525-528. View abstract.

Yu, S. Y., Zhu, Y. J., Li, W. G., Huang, Q. S., Huang, C. Z., Zhang, Q. N., and Hou, C. A preliminary report on the intervention trials of primary liver cancer in high-risk populations with nutritional supplementation of selenium in China. Biol.Trace Elem.Res. 1991;29(3):289-294. View abstract.

Negro, R., Greco, G., Mangieri, T., Pezzarossa, A., Dazzi, D., and Hassan, H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol.Metab 2007;92(4):1263-1268. View abstract.

Heyland, D. K., Dhaliwalm, R., Day, A., Drover, J., Cote, H., and Wischmeyer, P. Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. JPEN J Parenter.Enteral Nutr 2007;31(2):109-118. View abstract.

Joniau, S., Goeman, L., Roskams, T., Lerut, E., Oyen, R., and Van Poppel, H. Effect of nutritional supplement challenge in patients with isolated high-grade prostatic intraepithelial neoplasia. Urology 2007;69(6):1102-1106. View abstract.

Alexander, J. Selenium. Novartis.Found.Symp 2007;282:143-149. View abstract.

Flohe, L. Selenium in mammalian spermiogenesis. Biol.Chem. 2007;388(10):987-995. View abstract.

Sanchez-Gutierrez, M., Garcia-Montalvo, E. A., Izquierdo-Vega, J. A., and Del Razo, L. M. Effect of dietary selenium deficiency on the in vitro fertilizing ability of mice spermatozoa. Cell Biol.Toxicol. 2008;24(4):321-329. View abstract.

Beale, R. J., Sherry, T., Lei, K., Campbell-Stephen, L., McCook, J., Smith, J., Venetz, W., Alteheld, B., Stehle, P., and Schneider, H. Early enteral supplementation with key pharmaconutrients improves Sequential Organ Failure Assessment score in critically ill patients with sepsis: outcome of a randomized, controlled, double-blind trial. Crit Care Med. 2008;36(1):131-144. View abstract.

Voitsekhovskaia, IuG, Skesters, A., Orlikov, G. A., Silova, A. A., Rusakova, N. E., Larmane, L. T., Karpov, IuG, Ivanov, A. D., and Maulins, E. [Assessment of some oxidative stress parameters in bronchial asthma patients beyond add-on selenium supplementation]. Biomed Khim. 2007;53(5):577-584. View abstract.

Hawkes, W. C., Richter, B. D., Alkan, Z., Souza, E. C., Derricote, M., Mackey, B. E., and Bonnel, E. L. Response of selenium status indicators to supplementation of healthy North American men with high-selenium yeast. Biol Trace Elem.Res 2008;122(2):107-121. View abstract.

Salonen, J. T., Salonen, R., Seppanen, K., Rinta-Kiikka, S., Kuukka, M., Korpela, H., Alfthan, G., Kantola, M., and Schalch, W. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status. Am.J Clin.Nutr. 1991;53(5):1222-1229. View abstract.

Katzen-Luchenta, J. The declaration of nutrition, health, and intelligence for the child-to-be. Nutr.Health 2007;19(1-2):85-102. View abstract.

Thomson, A. Nutritional support in acute pancreatitis. Curr.Opin.Clin.Nutr.Metab Care 2008;11(3):261-266. View abstract.

Vincent, J. L. and Forceville, X. Critically elucidating the role of selenium. Curr Opin Anaesthesiol. 2008;21(2):148-154. View abstract.

Mahata, J., Argos, M., Verret, W., Kibriya, M. G., Santella, R. M., and Ahsan, H. Effect of selenium and vitamin e supplementation on plasma protein carbonyl levels in patients with arsenic-related skin lesions. Nutr Cancer 2008;60(1):55-60. View abstract.

Reid, M. E., Duffield-Lillico, A. J., Slate, E., Natarajan, N., Turnbull, B., Jacobs, E., Combs, G. F., Jr., Alberts, D. S., Clark, L. C., and Marshall, J. R. The nutritional prevention of cancer: 400 mcg per day selenium treatment. Nutr.Cancer 2008;60(2):155-163. View abstract.

Gosney, M. A., Hammond, M. F., Shenkin, A., and Allsup, S. Effect of micronutrient supplementation on mood in nursing home residents. Gerontology 2008;54(5):292-299. View abstract.

Gomm, S. A., Thatcher, N., Cuthbert, A., Chang, J., Burmester, H., Hall, P., and Carroll, K. B. High dose combination chemotherapy with ifosfamide, cyclophosphamide or cisplatin, mitomycin C and mustine with autologous bone marrow support in advanced non-small cell lung cancer. A phase I/II study. Br.J Cancer 1991;63(2):293-297. View abstract.

Kupka, R., Mugusi, F., Aboud, S., Msamanga, G. I., Finkelstein, J. L., Spiegelman, D., and Fawzi, W. W. Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and child outcomes. Am.J Clin.Nutr. 2008;87(6):1802-1808. View abstract.

Balazs, C. [The effect of selenium therapy on autoimmune thyroiditis]. Orv.Hetil. 6-29-2008;149(26):1227-1232. View abstract.

Burney, P., Potts, J., Makowska, J., Kowalski, M., Phillips, J., Gnatiuc, L., Shaheen, S., Joos, G., Van, Cauwenberge P., van, Zele T., Verbruggen, K., van, Durme Y., Derudder, I., Wohrl, S., Godnic-Cvar, J., Salameh, B., Skadhauge, L., Thomsen, G., Zuberbier, T., Bergmann, K. C., Heinzerling, L., Renz, H., Al-Fakhri, N., Kosche, B., Hildenberg, A., Papadopoulos, N. G., Xepapadaki, P., Zannikos, K., Gjomarkaj, M., Bruno, A., Pace, E., Bonini, S., Bresciani, M., Gramiccioni, C., Fokkens, W., Weersink, E. J., Carlsen, K. H., Bakkeheim, E., Loureiro, C., Villanueva, C. M., Sanjuas, C., Zock, J. P., Lundback, B., and Janson, C. A case-control study of the relation between plasma selenium and asthma in European populations: a GAL2EN project. Allergy 2008;63(7):865-871. View abstract.

Duntas, L. H. Environmental factors and autoimmune thyroiditis. Nat.Clin.Pract Endocrinol.Metab 2008;4(8):454-460. View abstract.

Orrell, R. W., Lane, R. J., and Ross, M. A systematic review of antioxidant treatment for amyotrophic lateral sclerosis/motor neuron disease. Amyotroph.Lateral.Scler. 2008;9(4):195-211. View abstract.

Daniels, L., Gibson, R. A., Simmer, K., Van, Dael P., and Makrides, M. Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial. Am.J Clin.Nutr. 2008;88(1):70-76. View abstract.

Navarro-Alarcon, M. and Cabrera-Vique, C. Selenium in food and the human body: a review. Sci Total Environ. 8-1-2008;400(1-3):115-141. View abstract.

Benton, D. and Cook, R. The impact of selenium supplementation on mood. Biol.Psychiatry 6-1-1991;29(11):1092-1098. View abstract.

Turner-McGrievy, G. M., Barnard, N. D., Cohen, J., Jenkins, D. J., Gloede, L., and Green, A. A. Changes in nutrient intake and dietary quality among participants with type 2 diabetes following a low-fat vegan diet or a conventional diabetes diet for 22 weeks. J Am.Diet.Assoc. 2008;108(10):1636-1645. View abstract.

Saliba, W., El, Fakih R., and Shaheen, W. Heart failure secondary to selenium deficiency, reversible after supplementation. Int J Cardiol. 5-28-2010;141(2):e26-e27. View abstract.

Kamble, P., Mohsin, N., Jha, A., Date, A., Upadhaya, A., Mohammad, E., Khalil, M., Pakkyara, A., and Budruddin, M. Selenium intoxication with selenite broth resulting in acute renal failure and severe gastritis. Saudi.J Kidney Dis.Transpl. 2009;20(1):106-111. View abstract.

Gartner, R. [Thyroid disorders during pregnancy]. Dtsch.Med Wochenschr. 2009;134(3):83-86. View abstract.

Hawkes, W. C., Alkan, Z., and Wong, K. Selenium supplementation does not affect testicular selenium status or semen quality in North American men. J Androl 2009;30(5):525-533. View abstract.

Schneider, M., Forster, H., Boersma, A., Seiler, A., Wehnes, H., Sinowatz, F., Neumuller, C., Deutsch, M. J., Walch, A., Hrabe de, Angelis M., Wurst, W., Ursini, F., Roveri, A., Maleszewski, M., Maiorino, M., and Conrad, M. Mitochondrial glutathione peroxidase 4 disruption causes male infertility. FASEB J 2009;23(9):3233-3242. View abstract.

Huston, R. K., Jelen, B. J., and Vidgoff, J. Selenium supplementation in low-birthweight premature infants: relationship to trace metals and antioxidant enzymes. JPEN J Parenter.Enteral Nutr 1991;15(5):556-559. View abstract.

Butler, J. A., Thomson, C. D., Whanger, P. D., and Robinson, M. F. Selenium distribution in blood fractions of New Zealand women taking organic or inorganic selenium. Am.J Clin.Nutr. 1991;53(3):748-754. View abstract.

Peretz, A., Neve, J., Desmedt, J., Duchateau, J., Dramaix, M., and Famaey, J. P. Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast. Am.J Clin.Nutr. 1991;53(5):1323-1328. View abstract.

Benton, D. and Cook, R. Selenium supplementation improves mood in a double-blind crossover trial. Psychopharmacology (Berl) 1990;102(4):549-550. View abstract.

Backman, E. and Henriksson, K. G. Effect of sodium selenite and vitamin E treatment in myotonic dystrophy. J Intern.Med 1990;228(6):577-581. View abstract.

Hill, J. and Bird, H. A. Failure of selenium-ace to improve osteoarthritis. Br.J Rheumatol. 1990;29(3):211-213. View abstract.

Fan, A. M. and Kizer, K. W. Selenium. Nutritional, toxicologic, and clinical aspects. West J Med 1990;153(2):160-167. View abstract.

Hommeren, O. J. [A comparative study of absorption of 2 organic selenium preparations and a placebo]. Tidsskr.Nor Laegeforen. 10-30-1990;110(26):3350-3351. View abstract.

Clausen, J., Nielsen, S. A., and Kristensen, M. Biochemical and clinical effects of an antioxidative supplementation of geriatric patients. A double blind study. Biol.Trace Elem.Res. 1989;20(1-2):135-151. View abstract.

Jackson, M. J., Coakley, J., Stokes, M., Edwards, R. H., and Oster, O. Selenium metabolism and supplementation in patients with muscular dystrophy. Neurology 1989;39(5):655-659. View abstract.

Fairris, G. M., Perkins, P. J., Lloyd, B., Hinks, L., and Clayton, B. E. The effect on atopic dermatitis of supplementation with selenium and vitamin E. Acta Derm.Venereol. 1989;69(4):359-362. View abstract.

Holness, D. L., Taraschuk, I. G., and Nethercott, J. R. Health status of copper refinery workers with specific reference to selenium exposure. Arch.Environ.Health 1989;44(5):291-297. View abstract.

Korpela, H., Kumpulainen, J., Jussila, E., Kemila, S., Kaariainen, M., Kaariainen, T., and Sotaniemi, E. A. Effect of selenium supplementation after acute myocardial infarction. Res.Commun.Chem.Pathol.Pharmacol. 1989;65(2):249-252. View abstract.

Fairris, G. M., Lloyd, B., Hinks, L., Perkins, P. J., and Clayton, B. E. The effect of supplementation with selenium and vitamin E in psoriasis. Ann Clin Biochem 1989;26 ( Pt 1):83-88. View abstract.

Backman, E., Nylander, E., Johansson, I., Henriksson, K. G., and Tagesson, C. Selenium and vitamin E treatment of Duchenne muscular dystrophy: no effect on muscle function. Acta Neurol Scand 1988;78(5):429-435. View abstract.

Gamstorp, I., Gustavson, K. H., Hellstrom, O., and Nordgren, B. A trial of selenium and vitamin E in boys with muscular dystrophy. J Child Neurol 1986;1(3):211-214. View abstract.

Orndahl, G., Sellden, U., Hallin, S., Wetterqvist, H., Rindby, A., and Selin, E. Myotonic dystrophy treated with selenium and vitamin E. Acta Med Scand 1986;219(4):407-414. View abstract.

Dworkin, B., Newman, L. J., Berezin, S., Rosenthal, W. S., Schwarz, S. M., and Weiss, L. Low blood selenium levels in patients with cystic fibrosis compared to controls and healthy adults. JPEN J Parenter.Enteral Nutr. 1987;11(1):38-41. View abstract.

Pentel, P., Fletcher, D., and Jentzen, J. Fatal acute selenium toxicity. J Forensic Sci 1985;30(2):556-562. View abstract.

Kumpulainen, J., Salmenpera, L., Siimes, M. A., Koivistoinen, P., and Perheentupa, J. Selenium status of exclusively breast-fed infants as influenced by maternal organic or inorganic selenium supplementation. Am.J Clin.Nutr. 1985;42(5):829-835. View abstract.

Orndahl, G., Rindby, A., and Selin, E. Selenium therapy of myotonic dystrophy. Acta Med Scand. 1983;213(3):237-239. View abstract.

Wilber, C. G. Toxicology of selenium: a review. Clin Toxicol. 1980;17(2):171-230. View abstract.

Robinson, M. F., Campbell, D. R., Stewart, R. D., Rea, H. M., Thomson, C. D., Snow, P. G., and Squires, I. H. Effect of daily supplements of selenium on patients with muscular complaints in Otago and Canterbury. N.Z.Med J 5-13-1981;93(683):289-292. View abstract.

Portal, B., Richard, M. J., Coudray, C., Arnaud, J., and Favier, A. Effect of double-blind cross-over selenium supplementation on lipid peroxidation markers in cystic fibrosis patients. Clin.Chim.Acta 1-31-1995;234(1-2):137-146. View abstract.

Van, Gossum A. and Neve, J. Low selenium status in alcoholic cirrhosis is correlated with aminopyrine breath test. Preliminary effects of selenium supplementation. Biol.Trace Elem.Res. 1995;47(1-3):201-207. View abstract.

Tessier, F., Hida, H., Favier, A., and Marconnet, P. Muscle GSH-Px activity after prolonged exercise, training, and selenium supplementation. Biol.Trace Elem.Res. 1995;47(1-3):279-285. View abstract.

Han, L. and Zhou, S. M. Selenium supplement in the prevention of pregnancy induced hypertension. Chin Med J (Engl) 1994;107(11):870-871. View abstract.

Kiremidjian-Schumacher, L., Roy, M., Wishe, H. I., Cohen, M. W., and Stotzky, G. Supplementation with selenium and human immune cell functions. II. Effect on cytotoxic lymphocytes and natural killer cells. Biol.Trace Elem.Res. 1994;41(1-2):115-127. View abstract.

Berger, M. M., Cavadini, C., Chiolero, R., Guinchard, S., Krupp, S., and Dirren, H. Influence of large intakes of trace elements on recovery after major burns. Nutrition 1994;10(4):327-334. View abstract.

Nyyssonen, K., Porkkala, E., Salonen, R., Korpela, H., and Salonen, J. T. Increase in oxidation resistance of atherogenic serum lipoproteins following antioxidant supplementation: a randomized double-blind placebo-controlled clinical trial. Eur.J Clin Nutr 1994;48(9):633-642. View abstract.

Hasselmark, L., Malmgren, R., Zetterstrom, O., and Unge, G. Selenium supplementation in intrinsic asthma. Allergy 1993;48(1):30-36. View abstract.

Bonomini, M., Forster, S., De Risio, F., Rychly, J., Nebe, B., Manfrini, V., Klinkmann, H., and Albertazzi, A. Effects of selenium supplementation on immune parameters in chronic uraemic patients on haemodialysis. Nephrol Dial.Transplant 1995;10(9):1654-1661. View abstract.

Iwanier, K. and Zachara, B. A. Selenium supplementation enhances the element concentration in blood and seminal fluid but does not change the spermatozoal quality characteristics in subfertile men. J Androl 1995;16(5):441-447. View abstract.

Srivastava, A. K., Gupta, B. N., Bihari, V., and Gaur, J. S. Generalized hair loss and selenium exposure. Vet.Hum.Toxicol. 1995;37(5):468-469. View abstract.

Delmas-Beauvieux, M. C., Peuchant, E., Couchouron, A., Constans, J., Sergeant, C., Simonoff, M., Pellegrin, J. L., Leng, B., Conri, C., and Clerc, M. The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene. Am.J Clin.Nutr. 1996;64(1):101-107. View abstract.

Daniels, L., Gibson, R., and Simmer, K. Randomised clinical trial of parenteral selenium supplementation in preterm infants. Arch Dis Child Fetal Neonatal Ed 1996;74(3):F158-F164. View abstract.

Monget, A. L., Richard, M. J., Cournot, M. P., Arnaud, J., Galan, P., Preziosi, P., Herbeth, B., Favier, A., and Hercberg, S. Effect of 6 month supplementation with different combinations of an association of antioxidant nutrients on biochemical parameters and markers of the antioxidant defence system in the elderly. The Geriatrie/Min.Vit.Aox Network. Eur.J Clin.Nutr. 1996;50(7):443-449. View abstract.

Margaritis, I., Tessier, F., Prou, E., Marconnet, P., and Marini, J. F. Effects of endurance training on skeletal muscle oxidative capacities with and without selenium supplementation. J Trace Elem.Med Biol. 1997;11(1):37-43. View abstract.

Girodon, F., Blache, D., Monget, A. L., Lombart, M., Brunet-Lecompte, P., Arnaud, J., Richard, M. J., and Galan, P. Effect of a two-year supplementation with low doses of antioxidant vitamins and/or minerals in elderly subjects on levels of nutrients and antioxidant defense parameters. J Am.Coll.Nutr. 1997;16(4):357-365. View abstract.

Engel, J. M., Menges, T., Neuhauser, C., Schaefer, B., and Hempelmann, G. [Effects of various feeding regimens in multiple trauma patients on septic complications and immune parameters]. Anasthesiol.Intensivmed.Notfallmed.Schmerzther. 1997;32(4):234-239. View abstract.

Gasmi, A., Garnier, R., Galliot-Guilley, M., Gaudillat, C., Quartenoud, B., Buisine, A., and Djebbar, D. Acute selenium poisoning. Vet Hum Toxicol 1997;39(5):304-308. View abstract.

Combs, G. F., Jr., Clark, L. C., and Turnbull, B. W. Reduction of cancer risk with an oral supplement of selenium. Biomed.Environ Sci 1997;10(2-3):227-234. View abstract.

Combs, G. F., Jr., Clark, L. C., and Turnbull, B. W. Reduction of cancer mortality and incidence by selenium supplementation. Med Klin 9-15-1997;92 Suppl 3:42-45. View abstract.

Meltzer, H. M., Folmer, M., Wang, S., Lie, O., Maage, A., Mundal, H. H., and Ydersbond, T. A. Supplementary selenium influences the response to fatty acid-induced oxidative stress in humans. Biol Trace Elem Res 1997;60(1-2):51-68. View abstract.

Heinle, K., Adam, A., Gradl, M., Wiseman, M., and Adam, O. [Selenium concentration in erythrocytes of patients with rheumatoid arthritis. Clinical and laboratory chemistry infection markers during administration of selenium]. Med Klin 9-15-1997;92 Suppl 3:29-31. View abstract.

Zimmermann, T., Albrecht, S., Kuhne, H., Vogelsang, U., Grutzmann, R., and Kopprasch, S. [Selenium administration in patients with sepsis syndrome. A prospective randomized study]. Med Klin 9-15-1997;92 Suppl 3:3-4. View abstract.

Johnson, M. A. and Porter, K. H. Micronutrient supplementation and infection in institutionalized elders. Nutr Rev. 1997;55(11 Pt 1):400-404. View abstract.

Galan, P., Preziosi, P., Monget, A. L., Richard, M. J., Arnaud, J., Lesourd, B., Girodon, F., Alferez, M. J., Bourgeois, C., Keller, H., Favier, A., and Hercberg, S. Effects of trace element and/or vitamin supplementation on vitamin and mineral status, free radical metabolism and immunological markers in elderly long term-hospitalized subjects. Geriatric Network MIN. VIT. AOX. Int J Vitam.Nutr.Res. 1997;67(6):450-460. View abstract.

Yamaguchi, T., Sano, K., Takakura, K., Saito, I., Shinohara, Y., Asano, T., and Yasuhara, H. Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke 1998;29(1):12-17. View abstract.

Saito, I., Asano, T., Sano, K., Takakura, K., Abe, H., Yoshimoto, T., Kikuchi, H., Ohta, T., and Ishibashi, S. Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. Neurosurgery 1998;42(2):269-277. View abstract.

Pakdaman, A. Symptomatic treatment of brain tumor patients with sodium selenite, oxygen, and other supportive measures. Biol.Trace Elem.Res. 1998;62(1-2):1-6. View abstract.

Gail, M. H., You, W. C., Chang, Y. S., Zhang, L., Blot, W. J., Brown, L. M., Groves, F. D., Heinrich, J. P., Hu, J., Jin, M. L., Li, J. Y., Liu, W. D., Ma, J. L., Mark, S. D., Rabkin, C. S., Fraumeni, J. F., Jr., and Xu, G. W. Factorial trial of three interventions to reduce the progression of precancerous gastric lesions in Shandong, China: design issues and initial data. Control Clin.Trials 1998;19(4):352-369. View abstract.

Scott, R., MacPherson, A., Yates, R. W., Hussain, B., and Dixon, J. The effect of oral selenium supplementation on human sperm motility. Br.J Urol. 1998;82(1):76-80. View abstract.

Bogye, G., Alfthan, G., and Machay, T. Randomized clinical trial of enteral yeast-selenium supplementation in preterm infants. Biofactors 1998;8(1-2):139-142. View abstract.

Apostolski, S., Marinkovic, Z., Nikolic, A., Blagojevic, D., Spasic, M. B., and Michelson, A. M. Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation. J Environ.Pathol.Toxicol.Oncol. 1998;17(3-4):325-329. View abstract.

Liu, X., Yin, S., and Li, G. [Effects of selenium supplement on acute lower respiratory tract infection caused by respiratory syncytial virus]. Zhonghua Yu Fang Yi.Xue.Za Zhi. 1997;31(6):358-361. View abstract.

Zima, T., Mestek, O., Nemecek, K., Bartova, V., Fialova, J., Tesar, V., and Suchanek, M. Trace elements in hemodialysis and continuous ambulatory peritoneal dialysis patients. Blood Purif. 1998;16(5):253-260. View abstract.

Stevic, Z., Nicolic, A., and Blagojevic, D. A controlled trial of combination of methionine and antioxidants in ALS patients. Jugoslovenska Medicinska Biohemija 2011;20(4):223-228.

Srivastava, K. C. Ascorbic acid enhances the formation of prostaglandin E1 in washed human platelets and prostacyclin in rat aortic rings. Prostaglandins Leukot Med 1985;18:227-233.

Bonelli, L., Camoriano, A., Ravelli, P., Missale, G., Bruzzi, P., and Aste, H. Reduction of the incidence of metachronous adenomas of the large bowel by means of antioxidants. Proceedings of International Selenium Tellurium Development Association 1998;91-94.

Carcillo, J. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J., Zimmerman, J., Newth, C. J., Harrison, R., Burr, J., Willson, D. F., and Nicholson, C. The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. Pediatr.Crit Care Med. 2012;13(2):165-173. View abstract.

Vostalova J, Vidlar A, Ulrichova J, et al. Use of selenium-silymarin mix reduces lower urinary tract symptoms and prostate specific antigen in men. Phytomedicine 2013;21:75-81. View abstract.

Kong Z, Wang F, Ji S, et al. Selenium supplementation for sepsis: A meta-analysis of randomized controlled trials. Am J Emerg Med 2013;31(8):1170-5. View abstract.

Lee EH, Myung SK, Jeon YJ, et al. Effects of selenium supplements on cancer prevention: Meta-analysis of randomized controlled trials. Nutr Cancer 2011;63(8):1185-95. View abstract.

Li YF, Dong Z, Chen C, et al. Organic selenium supplementation increases mercury excretion and decreases oxidative damage in long-term mercury exposed residents from Wanshan, China. Environ Sci Technol 2012;46(20):11313-8. View abstract.

Lotan Y, Goodman PJ, Youssef RF, et al. Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT. J Urol 2012;187(6):2005-10. View abstract.

Morgia G, Russo G, Voce S, et al. Serenoa repens, lycopene and selenium versus tamsulosin for the treatment of LUTS/BPH. An Italian multicenter double-blinded randomized study between single or combination therapy (PROCOMB trial). Prostate 2014;74(15):1471-80. View abstract .

Muecke R, Micke O, Schomburg L, et al. Impact of treatment planning target volumen (PTV) size on radiation induced diarrhea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial. Radiat Oncol 2013;8:72. View abstract.

Sirikonda NS, Patten WD, Phillips JR, Mullet CJ. Ketogenic diet: Rapid onset of selenium deficiency-induced cardiac decompensation. Pediatr Cardiol 2012;33(5):834-8. View abstract.

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Jamilian M, Mansury S, Bahmani F, Heidar Z, Amirani E, Asemi Z. The effects of probiotic and selenium co-supplementation on parameters of mental health, hormonal profiles, and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome. J Ovarian Res. 2018 Sep 14;11(1):80. View abstract.

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Kamali A, Amirani E, Asemi Z. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial. Biol Trace Elem Res 2019;191(2):331-7. doi: 10.1007/s12011-019-1636-7. View abstract.

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Karamali M, Dastyar F, Badakhsh MH, Aghadavood E, Amirani E, Asemi Z. The effects of selenium supplementation on gene expression related to insulin and lipid metabolism, and pregnancy outcomes in patients with gestational diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Biol Trace Elem Res. 2020;195(1):1-8. View abstract.

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Rashidi BH, Mohammad Hosseinzadeh F, Alipoor E, Asghari S, Yekaninejad MS, Hosseinzadeh-Attar MJ. Effects of selenium supplementation on asymmetric dimethylarginine and cardiometabolic risk factors in patients with polycystic ovary syndrome. Biol Trace Elem Res. 2020;196(2):430-437. View abstract.

Tian X, Li N, Su R, Dai C, Zhang R. Selenium supplementation may decrease thyroid peroxidase antibody titer via reducing oxidative stress in euthyroid patients with autoimmune thyroiditis. Int J Endocrinol. 2020;2020:9210572. View abstract.

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Almanza-Monterrubio M, Garnica-Hayashi L, Dávila-Camargo A, Nava-Castañeda Á. Oral selenium improved the disease activity in patients with mild Graves' orbitopathy. J Fr Ophtalmol 2021;44(5):643-651. View abstract.

Mousavi MA, Saghaleini SH, Mahmoodpoor A, Ghojazadeh M, Mousavi SN. Daily parenteral selenium therapy in critically ill patients: An updated systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN 2021;41:49-58. View abstract.

Jamilian H, Ghaderi A. The effects of probiotic and selenium co-supplementation on clinical and metabolic scales in chronic schizophrenia: a randomized, double-blind, placebo-controlled trial. Biol Trace Elem Res 2021;199(12):4430-4438. View abstract.

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Mostafa MF, Osman EA, Elkasem MMA, Seddik MI, Herdan R. The antioxidant effect of selenium on succinylcholine-related myalgia after adult sinuscopies: Randomized controlled double-blind trial. Pain Physician 2021;24(6):E743-E751. View abstract.

Huang JF, Hsu CP, Ouyang CH, et al. The impact of selenium supplementation on trauma patients-systematic review and meta-analysis. Nutrients 2022;14(2):342. View abstract.

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Sharifi-Razavi A, Karimi N, Jafarpour H. Evaluation of selenium supplementation in acute ischemic stroke outcome: An outcome assessor blind, randomized, placebo-controlled, feasibility study. Neurol India 2022;70(1):87-93. View abstract.

Sharma AP, Sharma G, Kumar R. Systematic review and meta-analysis on effect of carnitine, coenzyme Q10 and selenium on pregnancy and semen parameters in couples with idiopathic male infertility. Urology 2022;161:4-11. View abstract.

Omrani H, Golmohamadi S, Pasdar Y, Jasemi K, Almasi A. Effect of selenium supplementation on lipid profile in hemodialysis patients. J Renal Inj Prev. 2016;5(4):179-82. View abstract.

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Tara F, Rayman MP, Boskabadi H, et al. Selenium supplementation and premature (pre-labour) rupture of membranes: a randomised double-blind placebo-controlled trial. J Obstet Gynaecol. 2010;30(1):30-4. View abstract.

Xu X, Hendryx M, Liang X, Kahe K, Li Y, Luo J. Dietary selenium intake and thyroid cancer risk in postmenopausal women. Nutrition 2022;103-104:111840. View abstract.

Payer J, Jackuliak P, Kužma M, Džupon M, Vaňuga P. Supplementation with myo-inositol and Selenium improves the clinical conditions and biochemical features of women with or at risk for subclinical hypothyroidism. Front Endocrinol (Lausanne) 2022;13:1067029. View abstract.

Perri G, Hill TR, Mathers JC, et al. Long-Term Selenium-Yeast Supplementation Does Not Affect Bone Turnover Markers: A Randomized Placebo-Controlled Trial. J Bone Miner Res 2022;37(11):2165-2173. View abstract.

Ouyang J, Cai Y, Song Y, Gao Z, Bai R, Wang A. Potential Benefits of Selenium Supplementation in Reducing Insulin Resistance in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis. Nutrients 2022;14(22):4933. View abstract.

Pereira ME, Souza JV, Galiciolli MEA, et al. Effects of Selenium Supplementation in Patients with Mild Cognitive Impairment or Alzheimer's Disease: A Systematic Review and Meta-Analysis. Nutrients 2022;14(15):3205. View abstract.

Kelishadi MR, Ashtary-Larky D, Davoodi SH, Clark CCT, Asbaghi O. The effects of selenium supplementation on blood lipids and blood pressure in adults: A systematic review and dose-response meta-analysis of randomized control trials. J Trace Elem Med Biol 2022;74:127046. View abstract.

Zadeh Modarres S, Asemi Z, Heidar Z. The effects of selenium supplementation on glycemic control, serum lipoproteins and biomarkers of oxidative stress in infertile women diagnosed with polycystic ovary syndrome undergoing in vitro fertilization: A randomized, double-blind, placebo-controlled trial. Clin Nutr ESPEN 2022;51:92-96. View abstract.

Szymanski M, Domaracki P, Szymanska A, et al. The Role and Place of Antioxidants in the Treatment of Male Infertility Caused by Varicocele. J Clin Med. 2022 Oct 28;11(21):6391. View abstract.

Zavros A, Andreou E, Aphamis G, et al. The Effects of Zinc and Selenium Co-Supplementation on Resting Metabolic Rate, Thyroid Function, Physical Fitness, and Functional Capacity in Overweight and Obese People under a Hypocaloric Diet: A Randomized, Double-Blind, and Placebo-Controlled Trial. Nutrients 2023;15(14):3133. View abstract.

Li KP, Yang XS, Wu T. The Effect of Antioxidants on Sperm Quality Parameters and Pregnancy Rates for Idiopathic Male Infertility: A Network Meta-Analysis of Randomized Controlled Trials. Front Endocrinol (Lausanne). 2022 Feb 21;13:810242. View abstract.

Milani M, Colombo F; GFM-O-Trial Investigators Group: Chiara Baraldo (Padova), Mauro Barbareschi (Milano), et al. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study. Skin Res Technol 2023;29(6):e13381. View abstract.

Laky B, Bruckmann C, Blumenschein J, Durstberger G, Haririan H. Effect of a multi-nutrient supplement as an adjunct to nonsurgical treatment of periodontitis: A randomized placebo-controlled clinical trial. J Periodontol 2024; 95(2): 101-113. View abstract.

Filippini T, Fairweather-Tait S, Vinceti M. Selenium and immune function: a systematic review and meta-analysis of experimental human studies. Am J Clin Nutr 2023;117(1):93-110. View abstract.

Heidar Z, Hamzepour N, Zadeh Modarres S, et al. The Effects of Selenium Supplementation on Clinical Symptoms and Gene Expression Related to Inflammation and Vascular Endothelial Growth Factor in Infertile Women Candidate for In Vitro Fertilization. Biol Trace Elem Res 2020;193(2):319-325. View abstract.

Jamilian M, Razavi M, Fakhrie Kashan Z, Ghandi Y, Bagherian T, Asemi Z. Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Clin Endocrinol (Oxf) 2015;82(6):885-91. View abstract.

Khazdouz M, Daryani NE, Cheraghpour M, et al. The effect of selenium supplementation on disease activity and immune-inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis: a randomized, double-blind, placebo-controlled clinical trial. Eur J Nutr 2023;62(8):3125-3134. View abstract.

Kim M, Jeon H, Chung Y, et al. Efficacy of Acetylcysteine and Selenium in Aneurysmal Subarachnoid Hemorrhage Patients: A Prospective, Multicenter, Single Blind Randomized Controlled Trial. J Korean Med Sci 2023;38(21):e161. View abstract.

Kong XQ, Qiu GY, Yang ZB, Tan ZX, Quan XQ. Clinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis. Medicine (Baltimore) 2023;102(20):e33791. View abstract.

Mehrpooya M, Majmasanaye M, Faramarzi F, Eshraghi A, Faress F. Investigation of the Effect of Oral Selenium on the Reduction of Clinical Symptoms and Joint Pain in Patients With Rheumatoid Arthritis in the Iranian Population. J Clin Pharmacol 2023;63(11):1197-1204. View abstract.

Rabah HM, Mohamed DA, Mariah RA, et al. Novel insights into the synergistic effects of selenium nanoparticles and metformin treatment of letrozole - induced polycystic ovarian syndrome: targeting PI3K/Akt signalling pathway, redox status and mitochondrial dysfunction in ovarian tissue. Redox Rep 2023;28(1):2160569. View abstract.

Stoppe C, McDonald B, Meybohm P, et al. Effect of High-Dose Selenium on Postoperative Organ Dysfunction and Mortality in Cardiac Surgery Patients: The SUSTAIN CSX Randomized Clinical Trial. JAMA Surg 2023;158(3):235-244. View abstract.

Turcu G, Artenie C, Nowicka D, et al. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis. Eur J Dermatol 2023;33(S1):19-23. View abstract.

Vajdi M, Hassanizadeh S, Gholami Z, Bagherniya M. Selenium supplementation effect on glycemic control: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Pharmacol Res 2023;195:106888. View abstract.

Wu PY, Tan X, Wang M, Zheng X, Lou JH. Selenium supplementation for polycystic ovary syndrome: a meta-analysis of randomized controlled trials. Gynecol Endocrinol 2022;38(11):928-934. View abstract.

Zadeh Modarres S, Heidar Z, Foroozanfard F, Rahmati Z, Aghadavod E, Asemi Z. The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid in Infertile Polycystic Ovary Syndrome Women Candidate for In Vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial. Biol Trace Elem Res 2018;183(2):218-225. View abstract.

Zhao J, Dong L, Lin Z, et al. Effects of selenium supplementation on Polycystic Ovarian Syndrome: a systematic review and meta-analysis on randomized clinical trials. BMC Endocr Disord 2023;23(1):33. View abstract.

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