References
Methoxylated Flavones
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Robbins RC. Action in human blood of methoxylated flavones which confer disease resistance on both plants and animals: Concept of a dietary conditioned mechanism of defense against disease. Internat J Vit Nutr Res 1975;45:51-60. View abstract.
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Robbins RC. Specificities between blood cell adhesion in human diseases and antiadhesion action in vitro of methoxylated flavones. J Clin Pharmacol 1973;13:401-7.
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Robbins RC. In vitro effects of penta-, hexa-, and hepta-methoxylated flavones on aggregation of cells in blood from hospitalized patients. J Clin Pharmacol 1973;13:271-5.
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Manthey JA, Guthrie N. Antiproliferative effects of citrus flavonoids against six human cancer cell lines. J Agric Food Chem 2002;50:5837-43. View abstract.
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Kurowska EM, Manthey JA. Hypolipidemic Effects and Absorption of Citrus Polymethoxylated Flavones in Hamsters with Diet-Induced Hypercholesterolemia. J Agric Food Chem 2004;52:2879-86. View abstract.
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Takanaga H, Ohnishi A, Yamada S, et al. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol Exp Ther 2000;293:230-6. View abstract.
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Manthey JA, Cesar TB, Jackson E, Mertens-Talcott S. Pharmacokinetic study of nobiletin and tangeretin in rat serum by high-performance liquid chromatography-electrospray ionization-mass spectrometry. J Agric Food Chem 2011;59(1):145-51. View abstract.
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Ayatollahi AM, Ghanadian M, Att-Ur-Rahman R, Mesaik MA, Khalid AS, Adeli F. Methoxylated flavones from Salvia Mirzayanii Rech. f. and Esfand with immunosuppressive properties. Iran J Pharm Res 2015;14(3):955-60. View abstract.
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Wudtiwai B, Sripanidkulchai B, Kongtawelert P, Banjerdpongchai R. Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines. J Hematol Oncol 2011;4:52. View abstract.
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Feng SL, Yuan ZW, Yao XJ, et al. Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function. Pharmacol Res 2016;110:193-204. View abstract.
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Duan L, Dou LL, Yu KY, et al. Polymethoxyflavones in peel of Citrus reticulata 'Chachi' and their biological activities. Food Chem. 2017 Nov 1;234:254-261. View abstract.
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Seo SH, Lee YC, Moon HI. Acetyl-cholinesterase Inhibitory Activity of Methoxyflavones Isolated from Kaempferia parviflora. Nat Prod Commun. 2017 Jan;12(1):21-22. View abstract.
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Li Y, Ning J, Wang Y, et al. Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. Toxicol Lett. 2018 Sep 15;294:27-36. View abstract.
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Surichan S, Arroo RR, Tsatsakis AM, Androutsopoulos VP. Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1-mediated metabolism to the product 4' hydroxy tangeretin. Toxicol In Vitro. 2018 Aug;50:274-284. View abstract.
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Hamada Y, Nakajima M, Tsuzuki K, et al. Heptamethoxyflavone Reduces Phosphodiesterase Activity and T-Cell Growth in vitro. Int Arch Allergy Immunol. 2017;174(3-4):113-120. View abstract.
100679
Yoshizaki N, Hashizume R, Masaki H. A polymethoxyflavone mixture extracted from orange peels, mainly containing nobiletin, 3,3',4',5,6,7,8-heptamethoxyflavone and tangeretin, suppresses melanogenesis through the acidification of cell organelles, including melanosomes. J Dermatol Sci. 2017 Oct;88(1):78-84. View abstract.
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Wang H, Dong L, Qu F, et al. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Pharm Biol. 2020 Dec;58(1):352-356. View abstract.
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Bajraktari-Sylejmani G, Weiss J. Potential risk of food-drug interactions: Citrus polymethoxyflavones and flavanones as inhibitors of the organic anion transporting polypeptides (OATP) 1B1, 1B3, and 2B1. Eur J Drug Metab Pharmacokinet. 2020;45(6):809-815. View abstract.