References
Gymnema
2
Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
45
Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. View abstract.
46
Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300. View abstract.
47
Head KA. Type 1 diabetes: prevention of the disease and its complications. Townsend Letter for Doctors & Patients 1998;180:72-84.
48
Sinsheimer JE, Subba-Rao G, McIlhenny HM. Constitents from G sylvestre leaves: isolation and preliminary characterization of the gymnemic acids. J Pharmacol Sci 1970;59:622-8.
11292
Katsukawa H, Imoto T, Ninomiya Y. Induction of salivary gurmarin-binding proteins in rats fed gymnema-containing diets. Chem Senses 1999;24:387-92. View abstract.
11367
Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003;26:1277-94. View abstract.
12549
Persaud SJ, Al-Majed H, Raman A, Jones PM. Gymnema sylvestre stimulates insulin release in vitro by increased membrane permeability. J Endocrinol 1999;163:207-12. View abstract.
14859
Luo H, Kashiwagi A, Shibahara T, Yamada K. Decreased bodyweight without rebound and regulated lipoprotein metabolism by gymnemate in genetic multifactor syndrome animal. Mol Cell Biochem 2007;299:93-8. View abstract.
14860
Ananthan R, Baskar C, NarmathaBai V, et al. Antidiabetic effect of Gymnema montanum leaves: effect on lipid peroxidation induced oxidative stress in experimental diabetes. Pharmacol Res 2003;48:551-6. View abstract.
14861
Satdive RK, Abhilash P, Fulzele DP. Antimicrobial activity of Gymnema sylvestre leaf extract. Fitoterapia 2003;74:699-701. View abstract.
19153
Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180. View abstract.
42604
Preuss, H. G., Garis, R. I., Bramble, J. D., Bagchi, D., Bagchi, M., Rao, C. V., and Satyanarayana, S. Efficacy of a novel calcium/potassium salt of (-)-hydroxycitric acid in weight control. Int.J Clin.Pharmacol.Res. 2005;25(3):133-144. View abstract.
54551
Porchezhian, E. and Dobriyal, R. M. An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents. Pharmazie 2003;58(1):5-12. View abstract.
54552
Xie, J. T., Wang, A., Mehendale, S., Wu, J., Aung, H. H., Dey, L., Qiu, S., and Yuan, C. S. Anti-diabetic effects of Gymnema yunnanense extract. Pharmacol Res 2003;47(4):323-329. View abstract.
54553
Ananthan, R., Latha, M., Pari, L., Ramkumar, K. M., Baskar, C. G., and Bai, V. N. Effect of Gymnema montanum on blood glucose, plasma insulin, and carbohydrate metabolic enzymes in alloxan-induced diabetic rats. J Med Food 2003;6(1):43-49. View abstract.
54554
Gholap, S. and Kar, A. Effects of Inula racemosa root and Gymnema sylvestre leaf extracts in the regulation of corticosteroid induced diabetes mellitus: involvement of thyroid hormones. Pharmazie 2003;58(6):413-415. View abstract.
54555
Jiang, H. [Advances in the study on hypoglycemic constituents of Gymnema sylvestre (Retz.) Schult]. Zhong.Yao Cai. 2003;26(4):305-307. View abstract.
54556
Okabayashi, Y., Tani, S., Fujisawa, T., Koide, M., Hasegawa, H., Nakamura, T., Fujii, M., and Otsuki, M. Effect of Gymnema sylvestre, R.Br. on glucose homeostasis in rats. Diabetes Res Clin Pract 1990;9(2):143-148. View abstract.
54561
Yoshikawa, M., Murakami, T., Kadoya, M., Li, Y., Murakami, N., Yamahara, J., and Matsuda, H. Medicinal foodstuffs. IX. The inhibitors of glucose absorption from the leaves of Gymnema sylvestre R. BR. (Asclepiadaceae): structures of gymnemosides a and b. Chem.Pharm Bull.(Tokyo) 1997;45(10):1671-1676. View abstract.
54563
Baskaran, K, Ahamath, BK, Shanmugasundaram, KR, and et all. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharm 1990;30:295-305.
54566
Kothe A and Uppal R. Antidiabetic effects of Gymnema sylvestre in NIDDM - a short study. Indian J Homeopath Med 1997;32(1-2):61-62, 66.
54567
Khare AK, Tondon RN, and Tewari JP. Hypoglycaemic activity of an indigenous drug (Gymnema sylvestre, "Gurmar") in normal and diabetic persons. Indian J Physiol Pharm 1983;27:257-258.
54568
Shanmugasundaram ERB, Rajeswari G, Baskaran K, and et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharm 1990;30(3):281-294.
54569
Srivastava Y, Bhatt HV, Prem AS, and et al. Hypoglycemic and life-prolonging properties of Gymnema sylvestre leaf extract in diabetic rats. Israel J Med Sci 1985;21:540-542.
54570
Shanmugasundaram KR, Panneerselvam C, Samudram P, and et al. Enzyme changes and glucose utilisation in diabetic rabbits: the effect of Gymnema sylvestre, R.Br. J Ethnopharm 1983;7:205-234.
54571
Shanmugasundaram ERB, Gopinath KL, Shanmugasundaram KR, and et al. Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts. J Ethnopharm 1990;30:265-279.
54572
Chattopadhyay RR. Possible mechanism of antihyperglycemic effect of Gymnema sylvestre leaf extract, Part I. Gen Pharm 1998;31(3):495-496.
54573
Gupta SS and Variyar MC. Experimental studies on pituitary diabetes IV. Effect of Gymnema sylvestre and Coccinia indica against the hyperglycemia response of somatotrophin and corticotrophin hormones. Indian J Med Res 1964;52:200-207.
54574
Tominaga M, Kimura M, Sugiyama K, and et al. Effects of seishin-renshi-in and Gymnema sylvestre on insulin resistance in streptozotocin-induced diabetic rats. Diabet Res Clin Pract 1995;29:11-17.
54578
Bishayee, A and Chatterjee, M. Hypolipidaemic and antiatherosclerotic effects of oral gymnema sylvestre R. Br. leaf extract in albino rats fed a high fat diet. Phytother Res 1994;8:118-120.
54579
Terasawa H, Miyoshi M, and Imoto T. Effects of long-term administration of Gymnema sylvestre watery-extract on variations of body weight, plasma glucose, serum triglyceride, total cholesterol and insulin in Wistar fatty rats. Yonago Acta Med 1994;37:117-127.
54580
Wang LF, Luo H, Miyoshi M, and et al. Inhibitory effect of gymnemic acid on intestinal absorption of oleic acid in rats. Can J Physiol Pharmacol 1998;76:1017-1023.
54581
Sinsheimer JE, Rao GS, and McIlhenny HM. Constituents from Gymnema sylvestre leaves V. Isolation and preliminary characterization of the gymnemic acids. J Pharm Sci 1970;59(5):622-628.
54582
Murakami, N, Murakami, T, Kadoya, M, and et all. New hypoglycemic constituents in "gymnemic acid" from Gymnema sylvestre. Chem Pharm Bull 1996;44(2):469-471.
92119
Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. View abstract.
92120
Singh VK, Dwivedi P, Chaudhary BR, Singh R. Immunomodulatory effect of Gymnema sylvestre (R.Br.) leaf extract: an in vitro study in rat model. PLoS One. 2015;10(10): :e0139631. View abstract.
92121
Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285. View abstract.
92122
Arunachalam KD, Arun LB, Annamalai SK, Arunachalam AM. Potential anticancer properties of bioactive compounds of Gymnema sylvestre and its biofunctionalized silver nanoparticles. Int J Nanomedicine. 2014;10:31-41. View abstract.
92123
Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. View abstract.
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Nakamura Y, Tsumura Y, Tonogai Y, Shibata T. Fecal steroid excretion is increased in rats by oral administration of gymnemic acids contained in Gymnema sylvestre leaves. J Nutr 1999;129(6):1214-22. View abstract.
95005
Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. View abstract.
96235
Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54. View abstract.
96236
Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394. View abstract.
96237
Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. View abstract.
96238
Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. View abstract.
105346
Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;24(1):28-32. View abstract.
105347
Turner S, Diako C, Kruger R, Wong M, Wood W, Rutherfurd-Markwick K, Ali A. Consuming Gymnema sylvestre reduces the desire for high-sugar sweet foods. Nutrients. 2020;12(4):1046. View abstract.
110021
Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. View abstract.
110022
Devangan S, Varghese B, Johny E, Gurram S, Adela R. The effect of Gymnema sylvestre supplementation on glycemic control in type 2 diabetes patients: A systematic review and meta-analysis. Phytother Res 2021;35(12):6802-6812. View abstract.
112183
Turner S, Diako C, Kruger R, et al. The Effect of a 14-Day gymnema sylvestre Intervention to Reduce Sugar Cravings in Adults. Nutrients 2022;14(24):5287. View abstract.
112184
Zamani M, Ashtary-Larky D, Nosratabadi S, et al. The effects of Gymnema Sylvestre supplementation on lipid profile, glycemic control, blood pressure, and anthropometric indices in adults: A systematic review and meta-analysis. Phytother Res 2023;37(3):949-964. View abstract.